Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005912                                                              19     869
XP_005248577                                                           19     869
XP_005248576                                                           19     869
NP_001167573                                                           17    3301
NP_001167572                                                           17    3301
NP_085044                                                              17    3301
NP_000113                                                              17    4312
NP_065769                                                              17    4312
NP_002039                                                              17    4312
NP_001073890                                                           17    4312
XP_006722755                                                           17    4312
XP_006721134                                                           17    4312
XP_005255507                                                           17    4312
XP_005263675                                                           17    4312
NP_077005                                                              16    5631
NP_001264992                                                           16    7355
XP_006722588                                                           16    7355
XP_005257326                                                           16    7355
XP_005252025                                                           16    7355
NP_002117                                                              16    7355
NP_065816                                                              15    9605
NP_001229338                                                           15    9605
NP_006080                                                              15    9605
NP_003449                                                              15    9605
NP_006069                                                              15    9605
NP_056503                                                              15    9605
NP_689811                                                              15    9605
NP_001275708                                                           15    9605
NP_001094345                                                           15    9605
NP_872363                                                              15    9605
NP_001158058                                                           15    9605
NP_001275709                                                           15    9605
NP_073588                                                              15    9605
XP_006724521                                                           15    9605
XP_006724520                                                           15    9605
XP_005257163                                                           15    9605
XP_005257162                                                           15    9605
XP_005257160                                                           15    9605
XP_005257159                                                           15    9605
XP_005257157                                                           15    9605
XP_005257155                                                           15    9605
XP_005257154                                                           15    9605
XP_005257153                                                           15    9605
XP_005257152                                                           15    9605
XP_005271570                                                           15    9605
XP_005271569                                                           15    9605
XP_006718878                                                           15    9605
XP_005271568                                                           15    9605
XP_006713443                                                           15    9605
XP_006711681                                                           15    9605
XP_006711680                                                           15    9605
XP_005245637                                                           15    9605
XP_006710573                                                           15    9605
XP_006710572                                                           15    9605
XP_006710571                                                           15    9605
XP_006710570                                                           15    9605
XP_006710569                                                           15    9605
XP_006710568                                                           15    9605
XP_006710567                                                           15    9605
XP_006710566                                                           15    9605
XP_005245859                                                           15    9605
NP_001010867                                                           15    9605
>NP_005912
          Length = 1512

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SSRIKAPS 8
           SSRIKAPS
Sbjct: 397 SSRIKAPS 404
>XP_005248577
          Length = 1349

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SSRIKAPS 8
           SSRIKAPS
Sbjct: 234 SSRIKAPS 241
>XP_005248576
          Length = 1375

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SSRIKAPS 8
           SSRIKAPS
Sbjct: 260 SSRIKAPS 267
>NP_001167573
          Length = 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SRIKAPSH 9
          SR++AP+H
Sbjct: 82 SRLEAPAH 89
>NP_001167572
          Length = 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SRIKAPSH 9
          SR++AP+H
Sbjct: 82 SRLEAPAH 89
>NP_085044
          Length = 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SRIKAPSH 9
          SR++AP+H
Sbjct: 82 SRLEAPAH 89
>NP_000113
          Length = 782

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           SSR KAPS
Sbjct: 763 SSRSKAPS 770
>NP_065769
          Length = 1352

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKAPSH 9
            +KAPSH
Sbjct: 1006 VKAPSH 1011
>NP_002039
          Length = 345

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSRIKAPSH 9
           SSR + PSH
Sbjct: 100 SSRWRCPSH 108
>NP_001073890
          Length = 1703

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    RIKAPSH 9
            R+K PSH
Sbjct: 1416 RVKLPSH 1422
>XP_006722755
          Length = 1722

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    RIKAPSH 9
            R+K PSH
Sbjct: 1416 RVKLPSH 1422
>XP_006721134
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   IKAPSH 9
           +KAPSH
Sbjct: 743 VKAPSH 748
>XP_005255507
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   IKAPSH 9
           +KAPSH
Sbjct: 743 VKAPSH 748
>XP_005263675
          Length = 718

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           SSR KAPS
Sbjct: 699 SSRSKAPS 706
>NP_077005
          Length = 432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SRIKAPSH 9
           SRI AP H
Sbjct: 159 SRIPAPRH 166
>NP_001264992
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SRIKAPSH 9
           SR+ AP H
Sbjct: 597 SRVPAPHH 604
>XP_006722588
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SRIKAPSH 9
           SR+ AP H
Sbjct: 597 SRVPAPHH 604
>XP_005257326
          Length = 296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR  AP H
Sbjct: 127 SSRASAPLH 135
>XP_005252025
          Length = 826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SRIKAP 7
           SRIKAP
Sbjct: 491 SRIKAP 496
>NP_002117
          Length = 295

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR  AP H
Sbjct: 127 SSRASAPLH 135
>NP_065816
          Length = 5183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           S R+K+PS
Sbjct: 620 SPRVKSPS 627
>NP_001229338
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRIKAPSH 9
           SSR+  P+H
Sbjct: 621 SSRLSWPNH 629
>NP_006080
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SSRIKAP 7
           SSRIK P
Sbjct: 283 SSRIKPP 289
>NP_003449
          Length = 3926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSRIKAPS 8
            SSR +APS
Sbjct: 3440 SSRSRAPS 3447
>NP_006069
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 240 SSRSTEPSH 248
>NP_056503
          Length = 1060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SSRIKAP 7
           SSRI AP
Sbjct: 993 SSRINAP 999
>NP_689811
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 343 SSRRSEPSH 351
>NP_001275708
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 381 SSRRSEPSH 389
>NP_001094345
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 343 SSRRSEPSH 351
>NP_872363
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SRIKAPS 8
           SR+K+PS
Sbjct: 993 SRLKSPS 999
>NP_001158058
          Length = 3708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   SSRIKAP 7
           SSR+K P
Sbjct: 929 SSRVKGP 935
>NP_001275709
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 342 SSRRSEPSH 350
>NP_073588
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRIKAPSH 9
           SSR+  P+H
Sbjct: 620 SSRLSWPNH 628
>XP_006724521
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SSRIKAP 7
           SSRIK P
Sbjct: 283 SSRIKPP 289
>XP_006724520
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SSRIKAP 7
           SSRIK P
Sbjct: 283 SSRIKPP 289
>XP_005257163
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 270 SSRRSEPSH 278
>XP_005257162
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 381 SSRRSEPSH 389
>XP_005257160
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 342 SSRRSEPSH 350
>XP_005257159
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 342 SSRRSEPSH 350
>XP_005257157
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 343 SSRRSEPSH 351
>XP_005257155
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 380 SSRRSEPSH 388
>XP_005257154
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 381 SSRRSEPSH 389
>XP_005257153
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 381 SSRRSEPSH 389
>XP_005257152
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           SSR   PSH
Sbjct: 381 SSRRSEPSH 389
>XP_005271570
          Length = 1462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SRIKAPS 8
           SR+K+PS
Sbjct: 956 SRLKSPS 962
>XP_005271569
          Length = 1462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SRIKAPS 8
           SR+K+PS
Sbjct: 956 SRLKSPS 962
>XP_006718878
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SRIKAPS 8
           SR+K+PS
Sbjct: 993 SRLKSPS 999
>XP_005271568
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SRIKAPS 8
           SR+K+PS
Sbjct: 993 SRLKSPS 999
>XP_006713443
          Length = 3970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SSRIKAPS 8
            SSR +APS
Sbjct: 3484 SSRSRAPS 3491
>XP_006711681
          Length = 3448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   SSRIKAP 7
           SSR+K P
Sbjct: 929 SSRVKGP 935
>XP_006711680
          Length = 3617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   SSRIKAP 7
           SSR+K P
Sbjct: 838 SSRVKGP 844
>XP_005245637
          Length = 3683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   SSRIKAP 7
           SSR+K P
Sbjct: 929 SSRVKGP 935
>XP_006710573
          Length = 5177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           S R+K+PS
Sbjct: 620 SPRVKSPS 627
>XP_006710572
          Length = 5188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           S R+K+PS
Sbjct: 620 SPRVKSPS 627
>XP_006710571
          Length = 5194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           S R+K+PS
Sbjct: 620 SPRVKSPS 627
>XP_006710570
          Length = 5195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           S R+K+PS
Sbjct: 620 SPRVKSPS 627
>XP_006710569
          Length = 5212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           S R+K+PS
Sbjct: 620 SPRVKSPS 627
>XP_006710568
          Length = 5221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           S R+K+PS
Sbjct: 620 SPRVKSPS 627
>XP_006710567
          Length = 5222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           S R+K+PS
Sbjct: 620 SPRVKSPS 627
>XP_006710566
          Length = 5222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           S R+K+PS
Sbjct: 620 SPRVKSPS 627
>XP_005245859
          Length = 5223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSRIKAPS 8
           S R+K+PS
Sbjct: 620 SPRVKSPS 627
>NP_001010867
          Length = 356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SSRIKAPSH 9
           S +IK P H
Sbjct: 324 SEKIKGPLH 332
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.112    0.306 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 701,719
Number of extensions: 874
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package