Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              18    1482
NP_001166935                                                           17    3301
NP_060111                                                              17    3301
NP_001166934                                                           17    3301
NP_001166936                                                           17    3301
NP_001361                                                              17    3301
NP_060066                                                              17    3301
NP_001239029                                                           17    3301
NP_001239032                                                           17    3301
NP_001239031                                                           17    3301
XP_006719559                                                           17    3301
XP_006719558                                                           17    3301
XP_005269072                                                           17    3301
XP_005269071                                                           17    3301
XP_005269070                                                           17    3301
XP_006719557                                                           17    3301
XP_005269069                                                           17    3301
XP_006719556                                                           17    3301
XP_005269068                                                           17    3301
XP_005269067                                                           17    3301
XP_005269066                                                           17    3301
XP_005269065                                                           17    3301
XP_005269064                                                           17    3301
XP_006712019                                                           17    3301
NP_068781                                                              16    7355
NP_001153218                                                           16    7355
NP_001123292                                                           16    7355
NP_001269078                                                           16    7355
NP_001083                                                              16    7355
NP_001164224                                                           16    7355
NP_659454                                                              16    7355
XP_006725360                                                           16    7355
XP_006725359                                                           16    7355
XP_006725358                                                           16    7355
XP_006725357                                                           16    7355
XP_006725356                                                           16    7355
XP_006725355                                                           16    7355
XP_005258025                                                           16    7355
XP_006721575                                                           16    7355
XP_006721574                                                           16    7355
XP_006721573                                                           16    7355
XP_006721572                                                           16    7355
XP_006721571                                                           16    7355
XP_006721570                                                           16    7355
XP_006721569                                                           16    7355
NP_057079                                                              16    7355
NP_008986                                                              15    9605
NP_113626                                                              15    9605
NP_036347                                                              15    9605
NP_001245213                                                           15    9605
XP_006717660                                                           15    9605
XP_005272154                                                           15    9605
XP_005272153                                                           15    9605
XP_005272152                                                           15    9605
NP_001004686                                                           15    9605
NP_787107                                                              15    9605
NP_001001963                                                           15    9605
NP_001004687                                                           15    9605
>NP_004251
          Length = 1208

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSRAVAHIF 9
            SSRAVA IF
Sbjct: 1156 SSRAVARIF 1164
>NP_001166935
          Length = 1674

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>NP_060111
          Length = 1661

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>NP_001166934
          Length = 1637

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>NP_001166936
          Length = 1621

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>NP_001361
          Length = 4158

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           S RAV HI+
Sbjct: 237 SQRAVTHIY 245
>NP_060066
          Length = 1624

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RAVAHIF 9
           RA+AH+F
Sbjct: 115 RAIAHLF 121
>NP_001239029
          Length = 1637

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RAVAHIF 9
           RA+AH+F
Sbjct: 115 RAIAHLF 121
>NP_001239032
          Length = 1610

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RAVAHIF 9
           RA+AH+F
Sbjct: 115 RAIAHLF 121
>NP_001239031
          Length = 1623

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RAVAHIF 9
           RA+AH+F
Sbjct: 115 RAIAHLF 121
>XP_006719559
          Length = 1650

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_006719558
          Length = 1644

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_005269072
          Length = 1607

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_005269071
          Length = 1614

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_005269070
          Length = 1627

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_006719557
          Length = 1631

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_005269069
          Length = 1632

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_006719556
          Length = 1655

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_005269068
          Length = 1657

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_005269067
          Length = 1662

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_005269066
          Length = 1668

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_005269065
          Length = 1670

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_005269064
          Length = 1675

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SRAVAHIF 9
           SRAV H+F
Sbjct: 115 SRAVKHLF 122
>XP_006712019
          Length = 4158

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           S RAV HI+
Sbjct: 237 SQRAVTHIY 245
>NP_068781
          Length = 859

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 314 SSRKLRHVF 322
>NP_001153218
          Length = 813

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 268 SSRKLRHVF 276
>NP_001123292
          Length = 912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SSRAVAHIF 9
           +SRA+ H++
Sbjct: 895 ASRAIKHLY 903
>NP_001269078
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 96  SSRKLRHVF 104
>NP_001083
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 277 SSRKLRHVF 285
>NP_001164224
          Length = 405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SSRAVAH 7
           SSR VAH
Sbjct: 398 SSRCVAH 404
>NP_659454
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SSRAVAH 7
           SSR VAH
Sbjct: 418 SSRCVAH 424
>XP_006725360
          Length = 776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 224 SSRKLRHVF 232
>XP_006725359
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 268 SSRKLRHVF 276
>XP_006725358
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 268 SSRKLRHVF 276
>XP_006725357
          Length = 829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 277 SSRKLRHVF 285
>XP_006725356
          Length = 866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 314 SSRKLRHVF 322
>XP_006725355
          Length = 871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 326 SSRKLRHVF 334
>XP_005258025
          Length = 912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SSRAVAHIF 9
           +SRA+ H++
Sbjct: 895 ASRAIKHLY 903
>XP_006721575
          Length = 776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 224 SSRKLRHVF 232
>XP_006721574
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 268 SSRKLRHVF 276
>XP_006721573
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 268 SSRKLRHVF 276
>XP_006721572
          Length = 829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 277 SSRKLRHVF 285
>XP_006721571
          Length = 866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 314 SSRKLRHVF 322
>XP_006721570
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 573 SSRKLRHVF 581
>XP_006721569
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSRAVAHIF 9
           SSR + H+F
Sbjct: 573 SSRKLRHVF 581
>NP_057079
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  SSRAVAH 7
          SSRAV H
Sbjct: 19 SSRAVVH 25
>NP_008986
          Length = 1390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    SRAVAHI 8
            SRAV HI
Sbjct: 1208 SRAVIHI 1214
>NP_113626
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SRAVAH 7
           SRA+AH
Sbjct: 444 SRAIAH 449
>NP_036347
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SSRAVAH 7
           SSR VAH
Sbjct: 398 SSRQVAH 404
>NP_001245213
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SRAVAHIF 9
           SRA+ H F
Sbjct: 170 SRAINHFF 177
>XP_006717660
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    SRAVAHI 8
            SRAV HI
Sbjct: 1187 SRAVIHI 1193
>XP_005272154
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SRAVAH 7
           SRA+AH
Sbjct: 426 SRAIAH 431
>XP_005272153
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SRAVAH 7
           SRA+AH
Sbjct: 426 SRAIAH 431
>XP_005272152
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SRAVAH 7
           SRA+AH
Sbjct: 444 SRAIAH 449
>NP_001004686
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SRAVAHIF 9
           SRA+ H F
Sbjct: 170 SRAINHFF 177
>NP_787107
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SRAVAHIF 9
           SRA+ H F
Sbjct: 170 SRAIDHFF 177
>NP_001001963
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SRAVAHIF 9
           SRA+ H F
Sbjct: 170 SRAINHFF 177
>NP_001004687
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SRAVAHIF 9
           SRA+ H F
Sbjct: 170 SRAINHFF 177
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.128    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 371,310
Number of extensions: 303
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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