Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           18    1135
NP_004561                                                              18    1135
NP_001275703                                                           18    1135
XP_005253450                                                           18    1135
XP_006719151                                                           18    1135
NP_775105                                                              17    2528
NP_001036148                                                           17    2528
XP_006715506                                                           17    2528
XP_006715505                                                           17    2528
XP_006715504                                                           17    2528
XP_006715503                                                           17    2528
XP_006715502                                                           17    2528
XP_005270863                                                           17    3301
XP_005270862                                                           17    3301
XP_006710667                                                           17    3301
XP_006710666                                                           17    3301
NP_001139108                                                           17    3301
NP_733936                                                              16    5631
NP_001071                                                              16    5631
NP_950245                                                              16    5631
NP_001243057                                                           16    5631
NP_001243056                                                           16    5631
NP_001121683                                                           16    5631
NP_116258                                                              16    5631
XP_006716736                                                           16    5631
NP_061028                                                              16    7355
NP_065795                                                              16    7355
NP_001190187                                                           16    7355
NP_056178                                                              16    7355
NP_001139799                                                           16    7355
NP_001139798                                                           16    7355
NP_004680                                                              16    7355
NP_542172                                                              16    7355
XP_005264515                                                           16    7355
XP_005264513                                                           16    7355
NP_848519                                                              15    9605
NP_001164111                                                           15    9605
NP_036251                                                              15    9605
NP_001138890                                                           15    9605
NP_001164110                                                           15    9605
NP_001034892                                                           15    9605
NP_036221                                                              15    9605
NP_001264880                                                           15    9605
NP_001264876                                                           15    9605
NP_001264878                                                           15    9605
NP_783163                                                              15    9605
NP_037423                                                              15    9605
NP_001099022                                                           15    9605
NP_001099021                                                           15    9605
NP_001099020                                                           15    9605
NP_001099019                                                           15    9605
NP_001268366                                                           15    9605
NP_004730                                                              15    9605
NP_001264881                                                           15    9605
NP_001264877                                                           15    9605
NP_001264875                                                           15    9605
NP_060770                                                              15    9605
NP_001268367                                                           15    9605
NP_001264874                                                           15    9605
NP_008933                                                              15    9605
XP_006724234                                                           15    9605
XP_005261462                                                           15    9605
XP_005260314                                                           15    9605
XP_005251917                                                           15    9605
XP_006716612                                                           15    9605
XP_006716611                                                           15    9605
XP_006711818                                                           15    9605
XP_006711817                                                           15    9605
>NP_001275701
          Length = 1486

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSNQYLIQV 9
            SSN YLIQV
Sbjct: 1258 SSNLYLIQV 1266
>NP_004561
          Length = 1445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSNQYLIQV 9
            SSN YLIQV
Sbjct: 1217 SSNLYLIQV 1225
>NP_001275703
          Length = 1264

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSNQYLIQV 9
            SSN YLIQV
Sbjct: 1036 SSNLYLIQV 1044
>XP_005253450
          Length = 1486

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSNQYLIQV 9
            SSN YLIQV
Sbjct: 1258 SSNLYLIQV 1266
>XP_006719151
          Length = 1486

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSNQYLIQV 9
            SSN YLIQV
Sbjct: 1258 SSNLYLIQV 1266
>NP_775105
          Length = 1659

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSNQYLIQV 9
           SSNQ+LI V
Sbjct: 145 SSNQFLIYV 153
>NP_001036148
          Length = 1683

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSNQYLIQV 9
           SSNQ+LI V
Sbjct: 145 SSNQFLIYV 153
>XP_006715506
          Length = 1507

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSNQYLIQV 9
           SSNQ+LI V
Sbjct: 145 SSNQFLIYV 153
>XP_006715505
          Length = 1673

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSNQYLIQV 9
           SSNQ+LI V
Sbjct: 145 SSNQFLIYV 153
>XP_006715504
          Length = 1683

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSNQYLIQV 9
           SSNQ+LI V
Sbjct: 145 SSNQFLIYV 153
>XP_006715503
          Length = 1707

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSNQYLIQV 9
           SSNQ+LI V
Sbjct: 145 SSNQFLIYV 153
>XP_006715502
          Length = 1707

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSNQYLIQV 9
           SSNQ+LI V
Sbjct: 145 SSNQFLIYV 153
>XP_005270863
          Length = 391

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SSNQYLIQ 8
          SSN+YLI+
Sbjct: 91 SSNRYLIE 98
>XP_005270862
          Length = 431

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SSNQYLIQ 8
          SSN+YLI+
Sbjct: 91 SSNRYLIE 98
>XP_006710667
          Length = 446

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SSNQYLIQ 8
          SSN+YLI+
Sbjct: 91 SSNRYLIE 98
>XP_006710666
          Length = 446

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SSNQYLIQ 8
          SSN+YLI+
Sbjct: 91 SSNRYLIE 98
>NP_001139108
          Length = 440

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SSNQYLIQ 8
          SSN+YLI+
Sbjct: 91 SSNRYLIE 98
>NP_733936
          Length = 548

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SNQYLIQ 8
           SNQ+L+Q
Sbjct: 356 SNQFLVQ 362
>NP_001071
          Length = 535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SNQYLIQ 8
           SNQ+L+Q
Sbjct: 343 SNQFLVQ 349
>NP_950245
          Length = 384

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SNQYLIQV 9
           +NQY IQV
Sbjct: 329 ANQYSIQV 336
>NP_001243057
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SNQYLIQV 9
           +NQY IQV
Sbjct: 280 ANQYSIQV 287
>NP_001243056
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SNQYLIQV 9
           +NQY IQV
Sbjct: 280 ANQYSIQV 287
>NP_001121683
          Length = 554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SNQYLIQV 9
           SNQYL  V
Sbjct: 409 SNQYLFSV 416
>NP_116258
          Length = 583

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SNQYLIQV 9
           SNQYL  V
Sbjct: 438 SNQYLFSV 445
>XP_006716736
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SNQYLIQV 9
           SNQYL  V
Sbjct: 351 SNQYLFSV 358
>NP_061028
          Length = 632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NQYLIQV 9
           N YL+QV
Sbjct: 266 NSYLVQV 272
>NP_065795
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSNQYLIQ 8
          SSN YLI+
Sbjct: 18 SSNPYLIR 25
>NP_001190187
          Length = 430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSNQYLIQ 8
          SSN YLI+
Sbjct: 18 SSNPYLIR 25
>NP_056178
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YLIQ
Sbjct: 476 SRNSYLIQ 483
>NP_001139799
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YLIQ
Sbjct: 476 SRNSYLIQ 483
>NP_001139798
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YLIQ
Sbjct: 476 SRNSYLIQ 483
>NP_004680
          Length = 715

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSNQYLIQ 8
          SSN YLI+
Sbjct: 18 SSNPYLIR 25
>NP_542172
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SNQYLI 7
           SNQYL+
Sbjct: 272 SNQYLV 277
>XP_005264515
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSNQYLIQ 8
          SSN YLI+
Sbjct: 18 SSNPYLIR 25
>XP_005264513
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSNQYLIQ 8
          SSN YLI+
Sbjct: 18 SSNPYLIR 25
>NP_848519
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NQYLIQV 9
          NQY++Q+
Sbjct: 74 NQYVVQL 80
>NP_001164111
          Length = 243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NQYLIQV 9
          NQY++Q+
Sbjct: 61 NQYVVQL 67
>NP_036251
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NQYLIQV 9
          NQY++Q+
Sbjct: 61 NQYVVQL 67
>NP_001138890
          Length = 2481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SSNQYLIQ 8
            SSN+YL +
Sbjct: 1441 SSNEYLYE 1448
>NP_001164110
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NQYLIQV 9
          NQY++Q+
Sbjct: 61 NQYVVQL 67
>NP_001034892
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NQYLIQV 9
          NQY++Q+
Sbjct: 61 NQYVVQL 67
>NP_036221
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SSNQYLIQ 8
           + N+YL+Q
Sbjct: 666 AENEYLVQ 673
>NP_001264880
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_001264876
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_001264878
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_783163
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  SSNQYLIQ 8
          +SN+YL++
Sbjct: 18 ASNKYLVE 25
>NP_037423
          Length = 1443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NQYLIQV 9
           N+Y++QV
Sbjct: 615 NRYIVQV 621
>NP_001099022
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_001099021
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_001099020
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_001099019
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_001268366
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  SSNQYLIQ 8
          +SN+YL++
Sbjct: 18 ASNKYLVE 25
>NP_004730
          Length = 668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SSNQYLIQ 8
          SSN YL++
Sbjct: 18 SSNPYLVR 25
>NP_001264881
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_001264877
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_001264875
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_060770
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_001268367
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  SSNQYLIQ 8
          +SN+YL++
Sbjct: 18 ASNKYLVE 25
>NP_001264874
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SSNQYLIQ 8
           S N YL+Q
Sbjct: 243 SRNSYLVQ 250
>NP_008933
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  SSNQYLIQ 8
          +SN+YL++
Sbjct: 18 ASNKYLVE 25
>XP_006724234
          Length = 2363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SSNQYLIQ 8
            SSN+YL +
Sbjct: 1323 SSNEYLYE 1330
>XP_005261462
          Length = 2473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SSNQYLIQ 8
            SSN+YL +
Sbjct: 1441 SSNEYLYE 1448
>XP_005260314
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  SSNQYLIQ 8
          +SN+YL++
Sbjct: 18 ASNKYLVE 25
>XP_005251917
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NQYLIQV 9
          NQY++Q+
Sbjct: 61 NQYVVQL 67
>XP_006716612
          Length = 1365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NQYLIQV 9
           N+Y++QV
Sbjct: 537 NRYIVQV 543
>XP_006716611
          Length = 1440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NQYLIQV 9
           N+Y++QV
Sbjct: 615 NRYIVQV 621
>XP_006711818
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SSNQYLIQ 8
           + N+YL+Q
Sbjct: 487 AENEYLVQ 494
>XP_006711817
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   SSNQYLIQ 8
           + N+YL+Q
Sbjct: 487 AENEYLVQ 494
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.122    0.298 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 451,251
Number of extensions: 769
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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