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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_001138890                                                           17    3301
XP_006724234                                                           17    3301
XP_005261462                                                           17    3301
NP_001020278                                                           15    9605
NP_056655                                                              15    9605
NP_056656                                                              15    9605
NP_001102                                                              15    9605
NP_001180424                                                           15    9605
XP_006711176                                                           15    9605
XP_006711175                                                           15    9605
XP_006711174                                                           15    9605
XP_006711173                                                           15    9605
XP_006711172                                                           15    9605

>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSMKDRAME 9
            SSMKDRA E
Sbjct: 3141 SSMKDRATE 3149



>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSMKDRAME 9
            SSMKDRA E
Sbjct: 3133 SSMKDRATE 3141



>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSMKDRAME 9
            SSMKDRA E
Sbjct: 3094 SSMKDRATE 3102



>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSMKDRAME 9
            SSMKDRA E
Sbjct: 3173 SSMKDRATE 3181



>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSMKDRAME 9
            SSMKDRA E
Sbjct: 3186 SSMKDRATE 3194



>NP_001138890
          Length = 2481

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   MKDRAME 9
           MKDRA+E
Sbjct: 990 MKDRALE 996



>XP_006724234
          Length = 2363

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   MKDRAME 9
           MKDRA+E
Sbjct: 872 MKDRALE 878



>XP_005261462
          Length = 2473

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   MKDRAME 9
           MKDRA+E
Sbjct: 990 MKDRALE 996



>NP_001020278
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SMKDRAME 9
           S  DRAME
Sbjct: 680 SCSDRAME 687



>NP_056655
          Length = 1200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SMKDRAME 9
           S  DRAME
Sbjct: 949 SCSDRAME 956



>NP_056656
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SMKDRAME 9
           S  DRAME
Sbjct: 930 SCSDRAME 937



>NP_001102
          Length = 1226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SMKDRAME 9
           S  DRAME
Sbjct: 975 SCSDRAME 982



>NP_001180424
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SMKDRAME 9
           S  DRAME
Sbjct: 680 SCSDRAME 687



>XP_006711176
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SMKDRAME 9
           S  DRAME
Sbjct: 680 SCSDRAME 687



>XP_006711175
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SMKDRAME 9
           S  DRAME
Sbjct: 680 SCSDRAME 687



>XP_006711174
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SMKDRAME 9
           S  DRAME
Sbjct: 680 SCSDRAME 687



>XP_006711173
          Length = 1210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SMKDRAME 9
           S  DRAME
Sbjct: 959 SCSDRAME 966



>XP_006711172
          Length = 1236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SMKDRAME 9
           S  DRAME
Sbjct: 985 SCSDRAME 992



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.106    0.245 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 355,374
Number of extensions: 328
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)