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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1135
NP_444254                                                              18    1135
NP_444253                                                              18    1135
NP_444255                                                              18    1135
XP_005247551                                                           18    1135
XP_005247550                                                           18    1135
XP_006713712                                                           18    1135
XP_005247549                                                           18    1135
NP_001386                                                              16    5631
NP_005493                                                              16    5631
NP_003204                                                              16    5631
NP_958851                                                              16    5631
XP_005274712                                                           16    5631
XP_005251835                                                           16    5631
XP_006717058                                                           16    5631
XP_005251833                                                           16    5631
XP_005251831                                                           16    5631
XP_005251830                                                           16    5631
NP_001258491                                                           16    7355
NP_061894                                                              16    7355
NP_444260                                                              15    9605
NP_444259                                                              15    9605
NP_004377                                                              15    9605
NP_003027                                                              15    9605
NP_001191790                                                           15    9605
NP_001191791                                                           15    9605
NP_001191788                                                           15    9605
NP_005639                                                              15    9605
NP_001191792                                                           15    9605
NP_001191789                                                           15    9605
NP_001191787                                                           15    9605
NP_001191793                                                           15    9605
NP_001191786                                                           15    9605
XP_005259803                                                           15    9605
XP_005259802                                                           15    9605
XP_005251347                                                           15    9605
XP_005244832                                                           15    9605

>NP_444256
          Length = 1794

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SSMAMISG 8
            SSMAMISG
Sbjct: 1639 SSMAMISG 1646



>NP_444254
          Length = 1845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SSMAMISG 8
            SSMAMISG
Sbjct: 1690 SSMAMISG 1697



>NP_444253
          Length = 1914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SSMAMISG 8
            SSMAMISG
Sbjct: 1759 SSMAMISG 1766



>NP_444255
          Length = 1863

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SSMAMISG 8
            SSMAMISG
Sbjct: 1708 SSMAMISG 1715



>XP_005247551
          Length = 1855

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SSMAMISG 8
            SSMAMISG
Sbjct: 1700 SSMAMISG 1707



>XP_005247550
          Length = 1856

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SSMAMISG 8
            SSMAMISG
Sbjct: 1701 SSMAMISG 1708



>XP_006713712
          Length = 1923

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SSMAMISG 8
            SSMAMISG
Sbjct: 1769 SSMAMISG 1776



>XP_005247549
          Length = 1924

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SSMAMISG 8
            SSMAMISG
Sbjct: 1769 SSMAMISG 1776



>NP_001386
          Length = 384

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSMAMISGP 9
           SSMA + GP
Sbjct: 148 SSMAPVPGP 156



>NP_005493
          Length = 2261

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SSMAMISGP 9
            ++MA+I GP
Sbjct: 2055 TAMALIGGP 2063



>NP_003204
          Length = 434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSMAMISGP 9
           SSMA+  GP
Sbjct: 146 SSMALARGP 154



>NP_958851
          Length = 305

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SSMAMISGP 9
          SSMA+  GP
Sbjct: 17 SSMALARGP 25



>XP_005274712
          Length = 384

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSMAMISGP 9
           SSMA + GP
Sbjct: 148 SSMAPVPGP 156



>XP_005251835
          Length = 2074

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SSMAMISGP 9
            ++MA+I GP
Sbjct: 2057 TAMALIGGP 2065



>XP_006717058
          Length = 2100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SSMAMISGP 9
            ++MA+I GP
Sbjct: 2057 TAMALIGGP 2065



>XP_005251833
          Length = 2203

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SSMAMISGP 9
            ++MA+I GP
Sbjct: 1997 TAMALIGGP 2005



>XP_005251831
          Length = 2263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SSMAMISGP 9
            ++MA+I GP
Sbjct: 2057 TAMALIGGP 2065



>XP_005251830
          Length = 2263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SSMAMISGP 9
            ++MA+I GP
Sbjct: 2057 TAMALIGGP 2065



>NP_001258491
          Length = 123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SSMAMISG 8
          S++AM+SG
Sbjct: 31 SALAMVSG 38



>NP_061894
          Length = 147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SSMAMISG 8
          S++AM+SG
Sbjct: 31 SALAMVSG 38



>NP_444260
          Length = 154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3 MAMISG 8
         MAMISG
Sbjct: 1 MAMISG 6



>NP_444259
          Length = 153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3 MAMISG 8
         MAMISG
Sbjct: 1 MAMISG 6



>NP_004377
          Length = 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   MAMISGP 9
           MAM+ GP
Sbjct: 633 MAMLRGP 639



>NP_003027
          Length = 728

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SSMAMISGP 9
          SSM+ + GP
Sbjct: 27 SSMSSLGGP 35



>NP_001191790
          Length = 112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AMISGP 9
          AM+SGP
Sbjct: 44 AMLSGP 49



>NP_001191791
          Length = 112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AMISGP 9
          AM+SGP
Sbjct: 44 AMLSGP 49



>NP_001191788
          Length = 112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AMISGP 9
          AM+SGP
Sbjct: 44 AMLSGP 49



>NP_005639
          Length = 112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AMISGP 9
          AM+SGP
Sbjct: 44 AMLSGP 49



>NP_001191792
          Length = 96

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AMISGP 9
          AM+SGP
Sbjct: 28 AMLSGP 33



>NP_001191789
          Length = 112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AMISGP 9
          AM+SGP
Sbjct: 44 AMLSGP 49



>NP_001191787
          Length = 112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AMISGP 9
          AM+SGP
Sbjct: 44 AMLSGP 49



>NP_001191793
          Length = 96

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AMISGP 9
          AM+SGP
Sbjct: 28 AMLSGP 33



>NP_001191786
          Length = 112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AMISGP 9
          AM+SGP
Sbjct: 44 AMLSGP 49



>XP_005259803
          Length = 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   MAMISGP 9
           MAM+ GP
Sbjct: 633 MAMLRGP 639



>XP_005259802
          Length = 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   MAMISGP 9
           MAM+ GP
Sbjct: 633 MAMLRGP 639



>XP_005251347
          Length = 112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AMISGP 9
          AM+SGP
Sbjct: 44 AMLSGP 49



>XP_005244832
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SSMAMISGP 9
          SSM+ + GP
Sbjct: 27 SSMSSLGGP 35



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.114    0.300 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 390,906
Number of extensions: 320
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)