Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1935
NP_001005855                                                           18    1935
XP_006716142                                                           18    1935
XP_005250088                                                           18    1935
XP_006716141                                                           18    1935
XP_005250085                                                           18    1935
XP_006716140                                                           18    1935
XP_005250084                                                           18    1935
XP_005250083                                                           18    1935
XP_005250082                                                           18    1935
NP_001231892                                                           16    5631
NP_001104488                                                           16    5631
NP_660093                                                              16    5631
NP_892009                                                              16    5631
XP_006718429                                                           16    5631
XP_006718428                                                           16    5631
XP_006718427                                                           16    5631
NP_057567                                                              16    7355
NP_001265150                                                           16    7355
NP_006461                                                              16    7355
XP_006721525                                                           16    7355
XP_005256537                                                           16    7355
XP_005256536                                                           16    7355
XP_005265284                                                           16    7355
XP_005265283                                                           16    7355
XP_005265282                                                           16    7355
NP_005227                                                              15    9605
NP_005069                                                              15    9605
NP_065959                                                              15    9605
NP_001269910                                                           15    9605
NP_001269909                                                           15    9605
NP_001098662                                                           15    9605
NP_001269908                                                           15    9605
NP_001269911                                                           15    9605
NP_005640                                                              15    9605
NP_149990                                                              15    9605
NP_001073873                                                           15    9605
NP_001191149                                                           15    9605
XP_005254690                                                           15    9605
XP_006720728                                                           15    9605
XP_006720727                                                           15    9605
XP_005254679                                                           15    9605
XP_005254685                                                           15    9605
XP_006720726                                                           15    9605
XP_005254682                                                           15    9605
XP_006720725                                                           15    9605
XP_005254680                                                           15    9605
>NP_733751
          Length = 4911

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSLRANEKS 9
            SSL ANEKS
Sbjct: 2919 SSLLANEKS 2927
>NP_001005855
          Length = 387

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SLRANEKS 9
           SLR+NEKS
Sbjct: 372 SLRSNEKS 379
>XP_006716142
          Length = 4927

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSLRANEKS 9
            SSL ANEKS
Sbjct: 2936 SSLLANEKS 2944
>XP_005250088
          Length = 4928

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSLRANEKS 9
            SSL ANEKS
Sbjct: 2936 SSLLANEKS 2944
>XP_006716141
          Length = 4959

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSLRANEKS 9
            SSL ANEKS
Sbjct: 2936 SSLLANEKS 2944
>XP_005250085
          Length = 4979

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSLRANEKS 9
            SSL ANEKS
Sbjct: 2936 SSLLANEKS 2944
>XP_006716140
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSLRANEKS 9
            SSL ANEKS
Sbjct: 2936 SSLLANEKS 2944
>XP_005250084
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSLRANEKS 9
            SSL ANEKS
Sbjct: 2936 SSLLANEKS 2944
>XP_005250083
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSLRANEKS 9
            SSL ANEKS
Sbjct: 2935 SSLLANEKS 2943
>XP_005250082
          Length = 4983

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SSLRANEKS 9
            SSL ANEKS
Sbjct: 2936 SSLLANEKS 2944
>NP_001231892
          Length = 2488

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSL+ NEK
Sbjct: 503 SSLKGNEK 510
>NP_001104488
          Length = 2365

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSL+ NEK
Sbjct: 416 SSLKGNEK 423
>NP_660093
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSL+ NEK
Sbjct: 480 SSLKGNEK 487
>NP_892009
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSL+ NEK
Sbjct: 480 SSLKGNEK 487
>XP_006718429
          Length = 2416

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSL+ NEK
Sbjct: 431 SSLKGNEK 438
>XP_006718428
          Length = 2455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSL+ NEK
Sbjct: 503 SSLKGNEK 510
>XP_006718427
          Length = 2465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSL+ NEK
Sbjct: 480 SSLKGNEK 487
>NP_057567
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSLR+N K
Sbjct: 286 SSLRSNSK 293
>NP_001265150
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSLR+N K
Sbjct: 247 SSLRSNSK 254
>NP_006461
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSLRANEKS 9
           S L+AN+KS
Sbjct: 195 SRLQANQKS 203
>XP_006721525
          Length = 274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SSLRANEKS 9
          S L+AN+KS
Sbjct: 81 SRLQANQKS 89
>XP_005256537
          Length = 402

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SSLRANEKS 9
          S L+AN+KS
Sbjct: 33 SRLQANQKS 41
>XP_005256536
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SSLRANEKS 9
          S L+AN+KS
Sbjct: 81 SRLQANQKS 89
>XP_005265284
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSLR+N K
Sbjct: 247 SSLRSNSK 254
>XP_005265283
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSLR+N K
Sbjct: 286 SSLRSNSK 293
>XP_005265282
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLRANEK 8
           SSLR+N K
Sbjct: 286 SSLRSNSK 293
>NP_005227
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLRANEKS 9
           SLRA EK+
Sbjct: 312 SLRATEKA 319
>NP_005069
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 207 SLRASEK 213
>NP_065959
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 207 SLRASEK 213
>NP_001269910
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 200 SLRASEK 206
>NP_001269909
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 207 SLRASEK 213
>NP_001098662
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 207 SLRASEK 213
>NP_001269908
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 207 SLRASEK 213
>NP_001269911
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 151 SLRASEK 157
>NP_005640
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSLRANEKS 9
           SSLR +EK+
Sbjct: 227 SSLRKHEKN 235
>NP_149990
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSLRANEKS 9
           SSLR +E+S
Sbjct: 238 SSLRQHERS 246
>NP_001073873
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSLRANEKS 9
           SSL+ +EKS
Sbjct: 240 SSLKRHEKS 248
>NP_001191149
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSLRANEKS 9
           SSLR +E+S
Sbjct: 237 SSLRQHERS 245
>XP_005254690
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 207 SLRASEK 213
>XP_006720728
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 206 SLRASEK 212
>XP_006720727
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 212 SLRASEK 218
>XP_005254679
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 217 SLRASEK 223
>XP_005254685
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 217 SLRASEK 223
>XP_006720726
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 206 SLRASEK 212
>XP_005254682
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 217 SLRASEK 223
>XP_006720725
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 212 SLRASEK 218
>XP_005254680
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SLRANEK 8
           SLRA+EK
Sbjct: 217 SLRASEK 223
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.282   0.0971    0.209 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 373,374
Number of extensions: 460
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package