Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002040                                                              18    1482
NP_006475                                                              17    3301
NP_004705                                                              17    3301
NP_006474                                                              17    3301
NP_775806                                                              17    3301
NP_001244956                                                           17    3301
XP_005259455                                                           17    3301
XP_006723528                                                           17    3301
XP_006723527                                                           17    3301
XP_005259452                                                           17    3301
XP_005264229                                                           17    3301
NP_000078                                                              16    5631
NP_001136036                                                           16    5631
NP_612429                                                              16    5631
NP_775952                                                              16    5631
NP_689749                                                              16    5631
XP_005267356                                                           16    5631
XP_005248106                                                           16    5631
XP_005264958                                                           16    5631
XP_005264957                                                           16    5631
NP_066000                                                              16    7355
NP_001274353                                                           16    7355
NP_001272758                                                           16    7355
NP_001274364                                                           16    7355
NP_004355                                                              16    7355
NP_001252541                                                           16    7355
NP_057368                                                              16    7355
NP_004822                                                              16    7355
XP_006713781                                                           16    7355
NP_443157                                                              15    9605
NP_003283                                                              15    9605
NP_061889                                                              15    9605
NP_001158058                                                           15    9605
NP_065876                                                              15    9605
XP_005258543                                                           15    9605
XP_006726249                                                           15    9605
XP_005258542                                                           15    9605
XP_005258541                                                           15    9605
XP_005258540                                                           15    9605
XP_006726248                                                           15    9605
XP_005258539                                                           15    9605
XP_005258538                                                           15    9605
XP_005277301                                                           15    9605
XP_006726369                                                           15    9605
XP_005277300                                                           15    9605
XP_005277299                                                           15    9605
XP_005277298                                                           15    9605
XP_006726368                                                           15    9605
XP_005277297                                                           15    9605
XP_005277296                                                           15    9605
XP_006726331                                                           15    9605
XP_005277122                                                           15    9605
XP_005277120                                                           15    9605
XP_006726330                                                           15    9605
XP_005277119                                                           15    9605
XP_005277118                                                           15    9605
XP_006723060                                                           15    9605
XP_005278309                                                           15    9605
XP_005278307                                                           15    9605
XP_006723059                                                           15    9605
XP_005278306                                                           15    9605
XP_005278305                                                           15    9605
XP_006721802                                                           15    9605
XP_005264132                                                           15    9605
XP_006711681                                                           15    9605
XP_006711680                                                           15    9605
XP_005245637                                                           15    9605
XP_005245528                                                           15    9605
NP_056988                                                              15    9605
>NP_002040
          Length = 413

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSLEGTGAA 9
           SSL GTGAA
Sbjct: 319 SSLGGTGAA 327
>NP_006475
          Length = 601

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSL GTGA
Sbjct: 505 SSLPGTGA 512
>NP_004705
          Length = 629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSL GTGA
Sbjct: 533 SSLPGTGA 540
>NP_006474
          Length = 589

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSL GTGA
Sbjct: 493 SSLPGTGA 500
>NP_775806
          Length = 589

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLEGT A
Sbjct: 171 SSLEGTNA 178
>NP_001244956
          Length = 557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLEGT A
Sbjct: 171 SSLEGTNA 178
>XP_005259455
          Length = 629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSL GTGA
Sbjct: 533 SSLPGTGA 540
>XP_006723528
          Length = 649

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSL GTGA
Sbjct: 553 SSLPGTGA 560
>XP_006723527
          Length = 661

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSL GTGA
Sbjct: 565 SSLPGTGA 572
>XP_005259452
          Length = 689

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSL GTGA
Sbjct: 593 SSLPGTGA 600
>XP_005264229
          Length = 567

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLEGT A
Sbjct: 171 SSLEGTNA 178
>NP_000078
          Length = 690

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SS+EG GA
Sbjct: 675 SSIEGPGA 682
>NP_001136036
          Length = 759

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SS+EG GA
Sbjct: 744 SSIEGPGA 751
>NP_612429
          Length = 5795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SLEGTGAA 9
           SLE TGAA
Sbjct: 365 SLEETGAA 372
>NP_775952
          Length = 924

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SSLEGTGAA 9
          S L+GTGA+
Sbjct: 76 SVLQGTGAS 84
>NP_689749
          Length = 1462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LEGTGA 8
           LEGTGA
Sbjct: 111 LEGTGA 116
>XP_005267356
          Length = 5695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SLEGTGAA 9
           SLE TGAA
Sbjct: 265 SLEETGAA 272
>XP_005248106
          Length = 690

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SS+EG GA
Sbjct: 675 SSIEGPGA 682
>XP_005264958
          Length = 1462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LEGTGA 8
           LEGTGA
Sbjct: 154 LEGTGA 159
>XP_005264957
          Length = 1505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LEGTGA 8
           LEGTGA
Sbjct: 154 LEGTGA 159
>NP_066000
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  SSLEGTG 7
          S LEGTG
Sbjct: 34 SMLEGTG 40
>NP_001274353
          Length = 393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSLEGTGAA 9
           S+L+G GAA
Sbjct: 286 SALKGLGAA 294
>NP_001272758
          Length = 239

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSLEGTGAA 9
           S+L+G GAA
Sbjct: 132 SALKGLGAA 140
>NP_001274364
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSLEGTGAA 9
           S+L+G GAA
Sbjct: 237 SALKGLGAA 245
>NP_004355
          Length = 358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSLEGTGAA 9
           S+L+G GAA
Sbjct: 251 SALKGLGAA 259
>NP_001252541
          Length = 2371

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LEGTGAA 9
            +EGTGA+
Sbjct: 2365 MEGTGAS 2371
>NP_057368
          Length = 2376

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LEGTGAA 9
            +EGTGA+
Sbjct: 2370 MEGTGAS 2376
>NP_004822
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSLEGTGAA 9
           SSL+G+G A
Sbjct: 194 SSLDGSGHA 202
>XP_006713781
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  SSLEGTG 7
          S LEGTG
Sbjct: 34 SMLEGTG 40
>NP_443157
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>NP_003283
          Length = 2363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLEGTGAA 9
            S EGTG+A
Sbjct: 1988 SNEGTGSA 1995
>NP_061889
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SSLEGT 6
           SSLEGT
Sbjct: 383 SSLEGT 388
>NP_001158058
          Length = 3708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SLEGTGAA 9
           SLEG G A
Sbjct: 444 SLEGAGPA 451
>NP_065876
          Length = 1269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SLEGTGA 8
          SLEG GA
Sbjct: 27 SLEGEGA 33
>XP_005258543
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>XP_006726249
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 479 SSLESSGA 486
>XP_005258542
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 497 SSLESSGA 504
>XP_005258541
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 497 SSLESSGA 504
>XP_005258540
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 516 SSLESSGA 523
>XP_006726248
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 516 SSLESSGA 523
>XP_005258539
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>XP_005258538
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>XP_005277301
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>XP_006726369
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 479 SSLESSGA 486
>XP_005277300
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 497 SSLESSGA 504
>XP_005277299
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 497 SSLESSGA 504
>XP_005277298
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 516 SSLESSGA 523
>XP_006726368
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 516 SSLESSGA 523
>XP_005277297
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>XP_005277296
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>XP_006726331
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 479 SSLESSGA 486
>XP_005277122
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 497 SSLESSGA 504
>XP_005277120
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 516 SSLESSGA 523
>XP_006726330
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 516 SSLESSGA 523
>XP_005277119
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>XP_005277118
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>XP_006723060
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 479 SSLESSGA 486
>XP_005278309
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 497 SSLESSGA 504
>XP_005278307
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 516 SSLESSGA 523
>XP_006723059
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 516 SSLESSGA 523
>XP_005278306
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>XP_005278305
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSLEGTGA 8
           SSLE +GA
Sbjct: 534 SSLESSGA 541
>XP_006721802
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SSLEGT 6
           SSLEGT
Sbjct: 285 SSLEGT 290
>XP_005264132
          Length = 1219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SSLEGTGAA 9
          + +EG GAA
Sbjct: 24 AEIEGAGAA 32
>XP_006711681
          Length = 3448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SLEGTGAA 9
           SLEG G A
Sbjct: 444 SLEGAGPA 451
>XP_006711680
          Length = 3617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SLEGTGAA 9
           SLEG G A
Sbjct: 353 SLEGAGPA 360
>XP_005245637
          Length = 3683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SLEGTGAA 9
           SLEG G A
Sbjct: 444 SLEGAGPA 451
>XP_005245528
          Length = 2439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLEGTGAA 9
            S EGTG+A
Sbjct: 2064 SNEGTGSA 2071
>NP_056988
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SSLEGTGAA 9
          + +EG GAA
Sbjct: 24 AEIEGAGAA 32
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.288    0.109    0.266 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 682,214
Number of extensions: 1026
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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