Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000312                                                              19     869
NP_783864                                                              17    2528
XP_005262701                                                           17    2528
NP_689856                                                              17    3301
NP_776186                                                              17    4312
XP_006713658                                                           17    4312
NP_001182612                                                           16    5631
NP_003234                                                              16    5631
NP_001182613                                                           16    5631
NP_689524                                                              16    5631
NP_004237                                                              16    5631
XP_005256918                                                           16    5631
XP_006710931                                                           16    5631
XP_006710930                                                           16    5631
NP_009115                                                              16    7355
NP_005236                                                              16    7355
XP_006714202                                                           16    7355
XP_005262892                                                           16    7355
XP_005262891                                                           16    7355
XP_006713727                                                           16    7355
XP_006713018                                                           16    7355
XP_005264896                                                           16    7355
XP_006711845                                                           16    7355
NP_795713                                                              16    7355
NP_005682                                                              15    9605
NP_064693                                                              15    9605
NP_001035706                                                           15    9605
NP_997191                                                              15    9605
NP_001364                                                              15    9605
NP_001152956                                                           15    9605
NP_009121                                                              15    9605
NP_056127                                                              15    9605
XP_005255000                                                           15    9605
XP_005254998                                                           15    9605
XP_005253348                                                           15    9605
XP_005253347                                                           15    9605
XP_006719088                                                           15    9605
XP_005253346                                                           15    9605
XP_005253344                                                           15    9605
XP_005253345                                                           15    9605
XP_005253343                                                           15    9605
XP_005253341                                                           15    9605
XP_005269527                                                           15    9605
XP_005269526                                                           15    9605
XP_006714407                                                           15    9605
XP_006714406                                                           15    9605
XP_006714405                                                           15    9605
XP_005263349                                                           15    9605
XP_005263348                                                           15    9605
XP_005263347                                                           15    9605
XP_005263346                                                           15    9605
XP_005263345                                                           15    9605
XP_005263344                                                           15    9605
XP_005263343                                                           15    9605
XP_005263342                                                           15    9605
XP_005263341                                                           15    9605
XP_005263340                                                           15    9605
XP_005263339                                                           15    9605
XP_006711798                                                           15    9605
XP_006711682                                                           15    9605
>NP_000312
          Length = 928

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSIVFYNSV 9
           S IVFYNSV
Sbjct: 751 SIIVFYNSV 759
>NP_783864
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSIVFYNSV 9
           SSI FYN V
Sbjct: 953 SSIQFYNKV 961
>XP_005262701
          Length = 1035

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSIVFYNSV 9
           SSI FYN V
Sbjct: 944 SSIQFYNKV 952
>NP_689856
          Length = 1749

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SSIVFYN 7
            SS++FYN
Sbjct: 1230 SSLIFYN 1236
>NP_776186
          Length = 236

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  VFYNSV 9
          VFYNSV
Sbjct: 83 VFYNSV 88
>XP_006713658
          Length = 212

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  VFYNSV 9
          VFYNSV
Sbjct: 83 VFYNSV 88
>NP_001182612
          Length = 850

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IVFYNSV 9
           +V+YNS+
Sbjct: 516 VVYYNSI 522
>NP_003234
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IVFYNSV 9
           +V+YNS+
Sbjct: 517 VVYYNSI 523
>NP_001182613
          Length = 850

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IVFYNSV 9
           +V+YNS+
Sbjct: 516 VVYYNSI 522
>NP_689524
          Length = 226

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SSIVFYNSV 9
           S   FYNS+
Sbjct: 108 SGFTFYNSI 116
>NP_004237
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   IVFYNS 8
           +VFYNS
Sbjct: 233 VVFYNS 238
>XP_005256918
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  IVFYNS 8
          +VFYNS
Sbjct: 80 VVFYNS 85
>XP_006710931
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IVFYNSV 9
           +V+YNS+
Sbjct: 517 VVYYNSI 523
>XP_006710930
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IVFYNSV 9
           +V+YNS+
Sbjct: 517 VVYYNSI 523
>NP_009115
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SSIVFYNS 8
            SS+VFY +
Sbjct: 1164 SSVVFYQT 1171
>NP_005236
          Length = 4588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSIVFYNS 8
           SS++F NS
Sbjct: 734 SSVIFMNS 741
>XP_006714202
          Length = 4588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSIVFYNS 8
           SS++F NS
Sbjct: 734 SSVIFMNS 741
>XP_005262892
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSIVFYNS 8
           SS++F NS
Sbjct: 734 SSVIFMNS 741
>XP_005262891
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSIVFYNS 8
           SS++F NS
Sbjct: 734 SSVIFMNS 741
>XP_006713727
          Length = 224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SSIVFYNSV 9
           SS++FY ++
Sbjct: 119 SSVIFYETM 127
>XP_006713018
          Length = 998

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSIVFYNS 8
           SS+VFY +
Sbjct: 658 SSVVFYQT 665
>XP_005264896
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SSIVFYNS 8
           SS+VFY +
Sbjct: 773 SSVVFYQT 780
>XP_006711845
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSIVFYNSV 9
           SSIVF N++
Sbjct: 430 SSIVFVNTM 438
>NP_795713
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SSIVFYNSV 9
           SS++FY ++
Sbjct: 119 SSVIFYETM 127
>NP_005682
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSIVFYNSV 9
           +SIV+Y+++
Sbjct: 117 TSIVYYHNI 125
>NP_064693
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSIVFYNSV 9
           +SIV+Y+++
Sbjct: 117 TSIVYYHNI 125
>NP_001035706
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VFYNSV 9
           VFYNS+
Sbjct: 226 VFYNSL 231
>NP_997191
          Length = 1888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    SIVFYNSV 9
            ++ FYNS+
Sbjct: 1409 TVQFYNSI 1416
>NP_001364
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            S I+FYN
Sbjct: 1402 SQIMFYN 1408
>NP_001152956
          Length = 1736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    SIVFYNSV 9
            ++ FYNS+
Sbjct: 1409 TVQFYNSI 1416
>NP_009121
          Length = 1000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   IVFYNS 8
           I+FYNS
Sbjct: 539 ILFYNS 544
>NP_056127
          Length = 5005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005255000
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VFYNSV 9
           VFYNS+
Sbjct: 226 VFYNSL 231
>XP_005254998
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VFYNSV 9
           VFYNS+
Sbjct: 226 VFYNSL 231
>XP_005253348
          Length = 1229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSIVFYNSV 9
           +SIV+Y+++
Sbjct: 117 TSIVYYHNI 125
>XP_005253347
          Length = 1502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSIVFYNSV 9
           +SIV+Y+++
Sbjct: 117 TSIVYYHNI 125
>XP_006719088
          Length = 1536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSIVFYNSV 9
           +SIV+Y+++
Sbjct: 117 TSIVYYHNI 125
>XP_005253346
          Length = 1536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSIVFYNSV 9
           +SIV+Y+++
Sbjct: 117 TSIVYYHNI 125
>XP_005253344
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSIVFYNSV 9
           +SIV+Y+++
Sbjct: 117 TSIVYYHNI 125
>XP_005253345
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSIVFYNSV 9
           +SIV+Y+++
Sbjct: 117 TSIVYYHNI 125
>XP_005253343
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSIVFYNSV 9
           +SIV+Y+++
Sbjct: 117 TSIVYYHNI 125
>XP_005253341
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSIVFYNSV 9
           +SIV+Y+++
Sbjct: 117 TSIVYYHNI 125
>XP_005269527
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   IVFYNS 8
           I+FYNS
Sbjct: 492 ILFYNS 497
>XP_005269526
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   IVFYNS 8
           I+FYNS
Sbjct: 539 ILFYNS 544
>XP_006714407
          Length = 5004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2345 SSVSFYN 2351
>XP_006714406
          Length = 3680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_006714405
          Length = 4103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 1423 SSVSFYN 1429
>XP_005263349
          Length = 4410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 1730 SSVSFYN 1736
>XP_005263348
          Length = 4443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 1763 SSVSFYN 1769
>XP_005263347
          Length = 4640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263346
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2303 SSVSFYN 2309
>XP_005263345
          Length = 4991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263344
          Length = 5005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263343
          Length = 5009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263342
          Length = 5025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2345 SSVSFYN 2351
>XP_005263341
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263340
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263339
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_006711798
          Length = 4586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SSIVFYN 7
            S I+FYN
Sbjct: 1419 SQIMFYN 1425
>XP_006711682
          Length = 1739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    SIVFYNSV 9
            ++ FYNS+
Sbjct: 1260 TVQFYNSI 1267
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.129    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 447,734
Number of extensions: 748
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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