Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1135
XP_006716142                                                           18    1135
XP_005250088                                                           18    1135
XP_006716141                                                           18    1135
XP_005250085                                                           18    1135
XP_006716140                                                           18    1135
XP_005250084                                                           18    1135
XP_005250083                                                           18    1135
XP_005250082                                                           18    1135
NP_009106                                                              17    3301
NP_008841                                                              17    3301
NP_061173                                                              17    3301
XP_005255519                                                           17    3301
XP_005255518                                                           17    3301
XP_006716343                                                           17    3301
XP_005273449                                                           17    3301
XP_005273448                                                           17    3301
NP_001273376                                                           16    5631
NP_055537                                                              16    5631
NP_001273375                                                           16    5631
NP_001273374                                                           16    5631
NP_006538                                                              16    5631
NP_056948                                                              16    5631
XP_006715702                                                           16    5631
XP_006715701                                                           16    5631
XP_006715344                                                           16    5631
XP_006715343                                                           16    5631
XP_006715342                                                           16    5631
XP_006715341                                                           16    5631
XP_006715340                                                           16    5631
XP_006715339                                                           16    5631
XP_006715338                                                           16    5631
XP_005259704                                                           16    7355
XP_005248008                                                           16    7355
XP_006713927                                                           16    7355
NP_660334                                                              16    7355
NP_079243                                                              16    7355
NP_065816                                                              15    9605
NP_001139661                                                           15    9605
NP_001166246                                                           15    9605
NP_690004                                                              15    9605
NP_001139662                                                           15    9605
NP_006032                                                              15    9605
NP_005344                                                              15    9605
NP_060227                                                              15    9605
XP_006722564                                                           15    9605
XP_006722563                                                           15    9605
XP_005266783                                                           15    9605
XP_005266713                                                           15    9605
XP_006710573                                                           15    9605
XP_006710572                                                           15    9605
XP_006710571                                                           15    9605
XP_006710570                                                           15    9605
XP_006710569                                                           15    9605
XP_006710568                                                           15    9605
XP_006710567                                                           15    9605
XP_006710566                                                           15    9605
XP_005245859                                                           15    9605
NP_055728                                                              15    9605
>NP_733751
          Length = 4911

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSGSISKQL 9
            SSGSIS+QL
Sbjct: 1307 SSGSISEQL 1315
>XP_006716142
          Length = 4927

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSGSISKQL 9
            SSGSIS+QL
Sbjct: 1308 SSGSISEQL 1316
>XP_005250088
          Length = 4928

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSGSISKQL 9
            SSGSIS+QL
Sbjct: 1308 SSGSISEQL 1316
>XP_006716141
          Length = 4959

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSGSISKQL 9
            SSGSIS+QL
Sbjct: 1308 SSGSISEQL 1316
>XP_005250085
          Length = 4979

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSGSISKQL 9
            SSGSIS+QL
Sbjct: 1308 SSGSISEQL 1316
>XP_006716140
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSGSISKQL 9
            SSGSIS+QL
Sbjct: 1308 SSGSISEQL 1316
>XP_005250084
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSGSISKQL 9
            SSGSIS+QL
Sbjct: 1308 SSGSISEQL 1316
>XP_005250083
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSGSISKQL 9
            SSGSIS+QL
Sbjct: 1307 SSGSISEQL 1315
>XP_005250082
          Length = 4983

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSGSISKQL 9
            SSGSIS+QL
Sbjct: 1308 SSGSISEQL 1316
>NP_009106
          Length = 339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SSGSISKQ 8
           S+GS+SKQ
Sbjct: 308 SAGSVSKQ 315
>NP_008841
          Length = 1792

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSGSISKQL 9
            SSG+ISK L
Sbjct: 1657 SSGNISKDL 1665
>NP_061173
          Length = 1758

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSGSISKQL 9
            SSG+ISK L
Sbjct: 1623 SSGNISKDL 1631
>XP_005255519
          Length = 1796

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSGSISKQL 9
            SSG+ISK L
Sbjct: 1661 SSGNISKDL 1669
>XP_005255518
          Length = 1830

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SSGSISKQL 9
            SSG+ISK L
Sbjct: 1695 SSGNISKDL 1703
>XP_006716343
          Length = 257

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SSGSISKQ 8
           S+GS+SKQ
Sbjct: 226 SAGSVSKQ 233
>XP_005273449
          Length = 339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SSGSISKQ 8
           S+GS+SKQ
Sbjct: 308 SAGSVSKQ 315
>XP_005273448
          Length = 451

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SSGSISKQ 8
           S+GS+SKQ
Sbjct: 420 SAGSVSKQ 427
>NP_001273376
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 509 SEGNITKQL 517
>NP_055537
          Length = 1068

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 559 SEGNITKQL 567
>NP_001273375
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 543 SEGNITKQL 551
>NP_001273374
          Length = 1047

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 538 SEGNITKQL 546
>NP_006538
          Length = 579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSGSISKQ 8
           S GS+SKQ
Sbjct: 184 SPGSVSKQ 191
>NP_056948
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 509 SEGNITKQL 517
>XP_006715702
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSGSISKQ 8
          S GS+SKQ
Sbjct: 27 SPGSVSKQ 34
>XP_006715701
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSGSISKQ 8
           S GS+SKQ
Sbjct: 184 SPGSVSKQ 191
>XP_006715344
          Length = 625

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 543 SEGNITKQL 551
>XP_006715343
          Length = 1018

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 509 SEGNITKQL 517
>XP_006715342
          Length = 1018

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 509 SEGNITKQL 517
>XP_006715341
          Length = 1018

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 509 SEGNITKQL 517
>XP_006715340
          Length = 1018

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 509 SEGNITKQL 517
>XP_006715339
          Length = 1030

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 521 SEGNITKQL 529
>XP_006715338
          Length = 1052

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           S G+I+KQL
Sbjct: 543 SEGNITKQL 551
>XP_005259704
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SSGSISKQ 8
          +SGSIS+Q
Sbjct: 51 ASGSISQQ 58
>XP_005248008
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSGSISKQ 8
           S+G ISKQ
Sbjct: 186 SAGEISKQ 193
>XP_006713927
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSGSISKQ 8
           S+G ISKQ
Sbjct: 186 SAGEISKQ 193
>NP_660334
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSGSISKQ 8
           S+G ISKQ
Sbjct: 186 SAGEISKQ 193
>NP_079243
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SSGSISKQ 8
          +SGSIS+Q
Sbjct: 51 ASGSISQQ 58
>NP_065816
          Length = 5183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSGSISKQL 9
            SSGS+S  L
Sbjct: 1982 SSGSVSDHL 1990
>NP_001139661
          Length = 1815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GSISKQ 8
           GSISKQ
Sbjct: 332 GSISKQ 337
>NP_001166246
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SSGSISKQ 8
          +SGS+S+Q
Sbjct: 51 ASGSVSQQ 58
>NP_690004
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SSGSISKQ 8
          +SGS+S+Q
Sbjct: 51 ASGSVSQQ 58
>NP_001139662
          Length = 1660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GSISKQ 8
           GSISKQ
Sbjct: 332 GSISKQ 337
>NP_006032
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SGSISKQL 9
           SGS SKQL
Sbjct: 130 SGSGSKQL 137
>NP_005344
          Length = 1161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GSISKQL 9
           GSI KQL
Sbjct: 322 GSIQKQL 328
>NP_060227
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GSISKQ 8
           GSISKQ
Sbjct: 332 GSISKQ 337
>XP_006722564
          Length = 1628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GSISKQ 8
           GSISKQ
Sbjct: 332 GSISKQ 337
>XP_006722563
          Length = 1630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GSISKQ 8
           GSISKQ
Sbjct: 332 GSISKQ 337
>XP_005266783
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GSISKQ 8
           GSISKQ
Sbjct: 332 GSISKQ 337
>XP_005266713
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           +SGSI +QL
Sbjct: 594 TSGSILRQL 602
>XP_006710573
          Length = 5177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSGSISKQL 9
            SSGS+S  L
Sbjct: 1982 SSGSVSDHL 1990
>XP_006710572
          Length = 5188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSGSISKQL 9
            SSGS+S  L
Sbjct: 1982 SSGSVSDHL 1990
>XP_006710571
          Length = 5194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSGSISKQL 9
            SSGS+S  L
Sbjct: 1982 SSGSVSDHL 1990
>XP_006710570
          Length = 5195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSGSISKQL 9
            SSGS+S  L
Sbjct: 1982 SSGSVSDHL 1990
>XP_006710569
          Length = 5212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSGSISKQL 9
            SSGS+S  L
Sbjct: 1982 SSGSVSDHL 1990
>XP_006710568
          Length = 5221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSGSISKQL 9
            SSGS+S  L
Sbjct: 1982 SSGSVSDHL 1990
>XP_006710567
          Length = 5222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSGSISKQL 9
            SSGS+S  L
Sbjct: 1982 SSGSVSDHL 1990
>XP_006710566
          Length = 5222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSGSISKQL 9
            SSGS+S  L
Sbjct: 1982 SSGSVSDHL 1990
>XP_005245859
          Length = 5223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SSGSISKQL 9
            SSGS+S  L
Sbjct: 1982 SSGSVSDHL 1990
>NP_055728
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSGSISKQL 9
           +SGSI +QL
Sbjct: 594 TSGSILRQL 602
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.288    0.107    0.234 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 499,958
Number of extensions: 859
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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