Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_065681                                                              18    1482
NP_066124                                                              18    1482
XP_006717999                                                           18    1482
NP_055511                                                              17    2528
NP_001229416                                                           17    2528
NP_001229417                                                           17    2528
NP_055852                                                              17    2528
XP_005277723                                                           17    2528
XP_005270386                                                           17    2528
XP_005269712                                                           17    2528
XP_006717788                                                           17    2528
XP_005269710                                                           17    2528
XP_005269709                                                           17    2528
XP_005269708                                                           17    2528
XP_005269706                                                           17    2528
XP_005269705                                                           17    2528
XP_006718823                                                           17    3301
NP_003914                                                              17    4312
NP_001162                                                              16    5631
XP_005255367                                                           16    5631
XP_006725257                                                           16    5631
XP_006725256                                                           16    5631
NP_443130                                                              16    5631
NP_071882                                                              16    7355
NP_612355                                                              16    7355
NP_003611                                                              16    7355
NP_001275882                                                           16    7355
NP_065191                                                              16    7355
NP_001275884                                                           16    7355
NP_001275880                                                           16    7355
NP_775798                                                              16    7355
NP_056073                                                              16    7355
XP_005267440                                                           16    7355
XP_006717081                                                           16    7355
XP_006715358                                                           16    7355
XP_005264540                                                           16    7355
XP_006712138                                                           16    7355
XP_005264497                                                           16    7355
XP_005264496                                                           16    7355
XP_005263588                                                           16    7355
NP_005261                                                              15    9605
NP_002011                                                              15    9605
NP_891555                                                              15    9605
NP_001140                                                              15    9605
NP_001191332                                                           15    9605
NP_057204                                                              15    9605
NP_001191333                                                           15    9605
NP_003848                                                              15    9605
NP_899196                                                              15    9605
NP_066267                                                              15    9605
NP_006752                                                              15    9605
NP_570971                                                              15    9605
NP_149981                                                              15    9605
NP_006505                                                              15    9605
XP_005276442                                                           15    9605
XP_006725361                                                           15    9605
XP_006723005                                                           15    9605
XP_005260222                                                           15    9605
XP_005256841                                                           15    9605
XP_006720476                                                           15    9605
XP_003846543                                                           15    9605
XP_005269773                                                           15    9605
XP_006717866                                                           15    9605
XP_005269772                                                           15    9605
XP_006717851                                                           15    9605
XP_006717845                                                           15    9605
XP_005265428                                                           15    9605
XP_006712486                                                           15    9605
XP_006712485                                                           15    9605
>NP_065681
          Length = 1072

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSGARRASL 9
           SSGARR SL
Sbjct: 689 SSGARRPSL 697
>NP_066124
          Length = 1114

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSGARRASL 9
           SSGARR SL
Sbjct: 689 SSGARRPSL 697
>XP_006717999
          Length = 1207

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SSGARRASL 9
           SSGARR SL
Sbjct: 782 SSGARRPSL 790
>NP_055511
          Length = 458

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SGARRASL 9
           SGAR+ASL
Sbjct: 134 SGARKASL 141
>NP_001229416
          Length = 1837

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSGARRAS 8
            SSG+RRAS
Sbjct: 1195 SSGSRRAS 1202
>NP_001229417
          Length = 1892

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSGARRAS 8
            SSG+RRAS
Sbjct: 1195 SSGSRRAS 1202
>NP_055852
          Length = 1842

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSGARRAS 8
            SSG+RRAS
Sbjct: 1200 SSGSRRAS 1207
>XP_005277723
          Length = 458

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SGARRASL 9
           SGAR+ASL
Sbjct: 134 SGARKASL 141
>XP_005270386
          Length = 482

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SGARRASL 9
           SGAR+ASL
Sbjct: 158 SGARKASL 165
>XP_005269712
          Length = 1800

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSGARRAS 8
            SSG+RRAS
Sbjct: 1166 SSGSRRAS 1173
>XP_006717788
          Length = 1829

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSGARRAS 8
            SSG+RRAS
Sbjct: 1195 SSGSRRAS 1202
>XP_005269710
          Length = 1834

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSGARRAS 8
            SSG+RRAS
Sbjct: 1200 SSGSRRAS 1207
>XP_005269709
          Length = 1871

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSGARRAS 8
            SSG+RRAS
Sbjct: 1166 SSGSRRAS 1173
>XP_005269708
          Length = 1897

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSGARRAS 8
            SSG+RRAS
Sbjct: 1200 SSGSRRAS 1207
>XP_005269706
          Length = 1900

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSGARRAS 8
            SSG+RRAS
Sbjct: 1195 SSGSRRAS 1202
>XP_005269705
          Length = 1905

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SSGARRAS 8
            SSG+RRAS
Sbjct: 1200 SSGSRRAS 1207
>XP_006718823
          Length = 1011

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   GARRASL 9
           GARRASL
Sbjct: 175 GARRASL 181
>NP_003914
          Length = 365

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           SSG  RASL
Sbjct: 265 SSGGHRASL 273
>NP_001162
          Length = 1503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SSGARRAS 8
           SSG+R+AS
Sbjct: 397 SSGSRKAS 404
>XP_005255367
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SSGARRAS 8
           SSG+R+AS
Sbjct: 498 SSGSRKAS 505
>XP_006725257
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SSGARRAS 8
           SSG+R+AS
Sbjct: 498 SSGSRKAS 505
>XP_006725256
          Length = 979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SSGARRAS 8
           SSG+R+AS
Sbjct: 498 SSGSRKAS 505
>NP_443130
          Length = 650

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SSGARRAS 8
           SSGA RAS
Sbjct: 233 SSGATRAS 240
>NP_071882
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           SSG  RASL
Sbjct: 106 SSGCGRASL 114
>NP_612355
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SGARRAS 8
          SGARRA+
Sbjct: 38 SGARRAA 44
>NP_003611
          Length = 605

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SSGARRASL 9
           SSGA+ ASL
Sbjct: 558 SSGAQPASL 566
>NP_001275882
          Length = 824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SGARRAS 8
           SG+RRAS
Sbjct: 638 SGSRRAS 644
>NP_065191
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SGARRAS 8
           SG+RRAS
Sbjct: 672 SGSRRAS 678
>NP_001275884
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SGARRAS 8
           SG+RRAS
Sbjct: 318 SGSRRAS 324
>NP_001275880
          Length = 882

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SGARRAS 8
           SG+RRAS
Sbjct: 696 SGSRRAS 702
>NP_775798
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SGARRAS 8
          SG+RRAS
Sbjct: 21 SGSRRAS 27
>NP_056073
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SSGARRASL 9
          S GAR ASL
Sbjct: 16 SGGARLASL 24
>XP_005267440
          Length = 341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SGARRAS 8
          SG+RRAS
Sbjct: 21 SGSRRAS 27
>XP_006717081
          Length = 1209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SSGARRASL 9
          S GAR ASL
Sbjct: 16 SGGARLASL 24
>XP_006715358
          Length = 216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SSGARRAS 8
          S+G RRAS
Sbjct: 62 SAGTRRAS 69
>XP_005264540
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           SSG  RASL
Sbjct: 106 SSGCGRASL 114
>XP_006712138
          Length = 678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           SSG  RASL
Sbjct: 106 SSGCGRASL 114
>XP_005264497
          Length = 730

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SGARRAS 8
           SG+RRAS
Sbjct: 672 SGSRRAS 678
>XP_005264496
          Length = 739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SGARRAS 8
           SG+RRAS
Sbjct: 553 SGSRRAS 559
>XP_005263588
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SGARRAS 8
          SGARRA+
Sbjct: 38 SGARRAA 44
>NP_005261
          Length = 1586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GARRAS 8
           GARRAS
Sbjct: 965 GARRAS 970
>NP_002011
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GARRAS 8
           GARRAS
Sbjct: 991 GARRAS 996
>NP_891555
          Length = 1363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GARRAS 8
           GARRAS
Sbjct: 991 GARRAS 996
>NP_001140
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SSGARRASL 9
          S GAR ASL
Sbjct: 40 SLGARSASL 48
>NP_001191332
          Length = 1861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           S GAR ASL
Sbjct: 900 SLGARSASL 908
>NP_057204
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SSGARR 6
           SSGARR
Sbjct: 505 SSGARR 510
>NP_001191333
          Length = 1868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           S GAR ASL
Sbjct: 907 SLGARSASL 915
>NP_003848
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SGARRA 7
           SGARRA
Sbjct: 225 SGARRA 230
>NP_899196
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SSGARR 6
           SSGARR
Sbjct: 505 SSGARR 510
>NP_066267
          Length = 4377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           S GAR ASL
Sbjct: 906 SLGARSASL 914
>NP_006752
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  GARRAS 8
          GARRAS
Sbjct: 54 GARRAS 59
>NP_570971
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GARRAS 8
           GARRAS
Sbjct: 748 GARRAS 753
>NP_149981
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SSGARR 6
           SSGARR
Sbjct: 154 SSGARR 159
>NP_006505
          Length = 1956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSGARRAS 8
           +SG RRAS
Sbjct: 493 ASGKRRAS 500
>XP_005276442
          Length = 161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SGARRA 7
           SGARRA
Sbjct: 118 SGARRA 123
>XP_006725361
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  GARRAS 8
          GARRAS
Sbjct: 54 GARRAS 59
>XP_006723005
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SSGARR 6
           SSGARR
Sbjct: 154 SSGARR 159
>XP_005260222
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SSGARR 6
          SSGARR
Sbjct: 34 SSGARR 39
>XP_005256841
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  GARRAS 8
          GARRAS
Sbjct: 54 GARRAS 59
>XP_006720476
          Length = 933

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GARRAS 8
           GARRAS
Sbjct: 755 GARRAS 760
>XP_003846543
          Length = 161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SGARRA 7
           SGARRA
Sbjct: 118 SGARRA 123
>XP_005269773
          Length = 1867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           S GAR ASL
Sbjct: 906 SLGARSASL 914
>XP_006717866
          Length = 1877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           S GAR ASL
Sbjct: 924 SLGARSASL 932
>XP_005269772
          Length = 1885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           S GAR ASL
Sbjct: 924 SLGARSASL 932
>XP_006717851
          Length = 3513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SSGARRASL 9
          S GAR ASL
Sbjct: 40 SLGARSASL 48
>XP_006717845
          Length = 4397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SSGARRASL 9
           S GAR ASL
Sbjct: 924 SLGARSASL 932
>XP_005265428
          Length = 1959

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSGARRAS 8
           +SG RRAS
Sbjct: 496 ASGKRRAS 503
>XP_006712486
          Length = 1504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GARRAS 8
           GARRAS
Sbjct: 883 GARRAS 888
>XP_006712485
          Length = 1569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GARRAS 8
           GARRAS
Sbjct: 948 GARRAS 953
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.111    0.264 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 414,618
Number of extensions: 599
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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