Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004324                                                              19     869
XP_005250103                                                           19     869
XP_005250102                                                           19     869
NP_000746                                                              17    2528
NP_001244292                                                           17    2528
XP_005251766                                                           17    2528
XP_005251765                                                           17    2528
XP_005251764                                                           17    2528
XP_005251763                                                           17    2528
NP_689756                                                              17    3301
NP_001035194                                                           16    5631
NP_001273598                                                           15    9605
NP_001273599                                                           15    9605
NP_861522                                                              15    9605
NP_001273597                                                           15    9605
NP_003740                                                              15    9605
NP_110436                                                              15    9605
XP_006719684                                                           15    9605
XP_005265784                                                           15    9605
XP_005265778                                                           15    9605
>NP_004324
          Length = 766

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SSASMDSVT 9
           SSASMD+VT
Sbjct: 113 SSASMDTVT 121
>XP_005250103
          Length = 758

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SSASMDSVT 9
           SSASMD+VT
Sbjct: 113 SSASMDTVT 121
>XP_005250102
          Length = 767

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SSASMDSVT 9
           SSASMD+VT
Sbjct: 113 SSASMDTVT 121
>NP_000746
          Length = 626

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SASMDSVT 9
           SASMDS+T
Sbjct: 470 SASMDSLT 477
>NP_001244292
          Length = 605

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SASMDSVT 9
           SASMDS+T
Sbjct: 449 SASMDSLT 456
>XP_005251766
          Length = 605

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SASMDSVT 9
           SASMDS+T
Sbjct: 449 SASMDSLT 456
>XP_005251765
          Length = 605

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SASMDSVT 9
           SASMDS+T
Sbjct: 449 SASMDSLT 456
>XP_005251764
          Length = 622

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SASMDSVT 9
           SASMDS+T
Sbjct: 466 SASMDSLT 473
>XP_005251763
          Length = 627

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SASMDSVT 9
           SASMDS+T
Sbjct: 471 SASMDSLT 478
>NP_689756
          Length = 186

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SSASMDSVT 9
           S AS+DS+T
Sbjct: 104 SQASLDSIT 112
>NP_001035194
          Length = 4493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SSASMDSVT 9
            SSA++DS T
Sbjct: 3734 SSATLDSTT 3742
>NP_001273598
          Length = 945

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSASMDSVT 9
           SSA+MD  T
Sbjct: 705 SSATMDPTT 713
>NP_001273599
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSASMDSVT 9
           SSA+MD  T
Sbjct: 373 SSATMDPTT 381
>NP_861522
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSASMDSVT 9
           SSA+MD  T
Sbjct: 858 SSATMDPTT 866
>NP_001273597
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSASMDSVT 9
           SSA+MD  T
Sbjct: 758 SSATMDPTT 766
>NP_003740
          Length = 1338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSASMDSVT 9
           SSAS+D  T
Sbjct: 591 SSASLDEYT 599
>NP_110436
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SSASMDS 7
           SSAS+DS
Sbjct: 345 SSASLDS 351
>XP_006719684
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SSASMDS 7
           SSAS+DS
Sbjct: 345 SSASLDS 351
>XP_005265784
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSASMDSVT 9
           SSA+MD  T
Sbjct: 481 SSATMDPTT 489
>XP_005265778
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSASMDSVT 9
           SSA+MD  T
Sbjct: 858 SSATMDPTT 866
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.280   0.0875    0.183 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 302,763
Number of extensions: 281
Number of successful extensions: 20
Number of sequences better than 10000.0: 20
Number of HSP's gapped: 20
Number of HSP's successfully gapped: 20
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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