Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000129                                                              17    2528
XP_006723106                                                           17    3301
XP_006723105                                                           17    3301
NP_604393                                                              17    3301
NP_005553                                                              17    4312
NP_061486                                                              17    4312
NP_937762                                                              17    4312
NP_001121189                                                           17    4312
NP_203748                                                              17    4312
XP_006711379                                                           17    4312
XP_005245207                                                           17    4312
NP_001123616                                                           16    5631
NP_671736                                                              16    5631
NP_004458                                                              16    5631
NP_066548                                                              16    5631
NP_963847                                                              16    5631
NP_963846                                                              16    5631
NP_001157738                                                           16    5631
XP_005273507                                                           16    5631
NP_777576                                                              16    7355
NP_056100                                                              16    7355
NP_443066                                                              16    7355
NP_001229416                                                           16    7355
NP_001229417                                                           16    7355
NP_055852                                                              16    7355
XP_006722494                                                           16    7355
XP_005269712                                                           16    7355
XP_006717788                                                           16    7355
XP_005269710                                                           16    7355
XP_005269709                                                           16    7355
XP_005269708                                                           16    7355
XP_005269706                                                           16    7355
XP_005269705                                                           16    7355
NP_000205                                                              15    9605
NP_000531                                                              15    9605
NP_001036188                                                           15    9605
NP_004095                                                              15    9605
NP_057613                                                              15    9605
NP_004842                                                              15    9605
NP_055722                                                              15    9605
NP_001243779                                                           15    9605
NP_001258934                                                           15    9605
NP_596869                                                              15    9605
NP_056379                                                              15    9605
NP_003449                                                              15    9605
NP_663622                                                              15    9605
NP_001073922                                                           15    9605
NP_001036009                                                           15    9605
NP_115823                                                              15    9605
NP_001036010                                                           15    9605
NP_003564                                                              15    9605
NP_839947                                                              15    9605
XP_006723382                                                           15    9605
XP_006723381                                                           15    9605
XP_006723380                                                           15    9605
XP_006722988                                                           15    9605
XP_006719899                                                           15    9605
XP_006719898                                                           15    9605
XP_006719897                                                           15    9605
XP_006719895                                                           15    9605
XP_005266476                                                           15    9605
XP_005271774                                                           15    9605
XP_005271772                                                           15    9605
XP_005251161                                                           15    9605
XP_005251160                                                           15    9605
XP_005251159                                                           15    9605
XP_005263256                                                           15    9605
XP_006713443                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
NP_001103447                                                           15    9605
NP_001138560                                                           15    9605
NP_001254479                                                           15    9605
>NP_000129
          Length = 2871

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           +SAEY  LC
Sbjct: 703 NSAEYQALC 711

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SSAEYSILC 9
            +++EY ILC
Sbjct: 1581 NTSEYKILC 1589
>XP_006723106
          Length = 971

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSAEYSILC 9
           S+++YS++C
Sbjct: 652 STSDYSLIC 660
>XP_006723105
          Length = 1028

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSAEYSILC 9
           S+++YS++C
Sbjct: 652 STSDYSLIC 660
>NP_604393
          Length = 994

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SSAEYSILC 9
           S+++YS++C
Sbjct: 618 STSDYSLIC 626
>NP_005553
          Length = 1193

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SSAEYSI 7
           SSAEYS+
Sbjct: 198 SSAEYSV 204
>NP_061486
          Length = 1111

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SSAEYSI 7
           SSAEYS+
Sbjct: 198 SSAEYSV 204
>NP_937762
          Length = 3333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SAEYSILC 9
           S  YS+LC
Sbjct: 991 SCNYSVLC 998
>NP_001121189
          Length = 3277

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SAEYSILC 9
           S  YS+LC
Sbjct: 991 SCNYSVLC 998
>NP_203748
          Length = 883

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  SAEYSILC 9
          S EY +LC
Sbjct: 6  SQEYGVLC 13
>XP_006711379
          Length = 1208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SSAEYSI 7
           SSAEYS+
Sbjct: 261 SSAEYSV 267
>XP_005245207
          Length = 1256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SSAEYSI 7
           SSAEYS+
Sbjct: 261 SSAEYSV 267
>NP_001123616
          Length = 1303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           SSAE+  LC
Sbjct: 963 SSAEFHSLC 971
>NP_671736
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+S+ C
Sbjct: 104 SPAEFSVYC 112
>NP_004458
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+S+ C
Sbjct: 104 SPAEFSVYC 112
>NP_066548
          Length = 1256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           SSAE+  LC
Sbjct: 963 SSAEFHSLC 971
>NP_963847
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+S+ C
Sbjct: 104 SPAEFSVYC 112
>NP_963846
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+S+ C
Sbjct: 104 SPAEFSVYC 112
>NP_001157738
          Length = 1139

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           SSAE+  LC
Sbjct: 846 SSAEFHSLC 854
>XP_005273507
          Length = 362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+S+ C
Sbjct: 154 SPAEFSVYC 162
>NP_777576
          Length = 1749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    SSAEYSILC 9
            +  EYS LC
Sbjct: 1533 AEGEYSALC 1541
>NP_056100
          Length = 1490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SAEYSILC 9
           + +YS+LC
Sbjct: 243 AGDYSLLC 250
>NP_443066
          Length = 1457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SAEYSILC 9
           + +YS+LC
Sbjct: 243 AGDYSLLC 250
>NP_001229416
          Length = 1837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+ +LC
Sbjct: 971 SEAEHPLLC 979
>NP_001229417
          Length = 1892

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+ +LC
Sbjct: 971 SEAEHPLLC 979
>NP_055852
          Length = 1842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+ +LC
Sbjct: 976 SEAEHPLLC 984
>XP_006722494
          Length = 1490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SAEYSILC 9
           + +YS+LC
Sbjct: 243 AGDYSLLC 250
>XP_005269712
          Length = 1800

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+ +LC
Sbjct: 942 SEAEHPLLC 950
>XP_006717788
          Length = 1829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+ +LC
Sbjct: 971 SEAEHPLLC 979
>XP_005269710
          Length = 1834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+ +LC
Sbjct: 976 SEAEHPLLC 984
>XP_005269709
          Length = 1871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+ +LC
Sbjct: 942 SEAEHPLLC 950
>XP_005269708
          Length = 1897

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+ +LC
Sbjct: 976 SEAEHPLLC 984
>XP_005269706
          Length = 1900

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+ +LC
Sbjct: 971 SEAEHPLLC 979
>XP_005269705
          Length = 1905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SSAEYSILC 9
           S AE+ +LC
Sbjct: 976 SEAEHPLLC 984
>NP_000205
          Length = 1218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SAEYSI 7
           SAEYSI
Sbjct: 993 SAEYSI 998
>NP_000531
          Length = 5038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4    EYSILC 9
            E+S+LC
Sbjct: 3397 EFSVLC 3402
>NP_001036188
          Length = 5033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4    EYSILC 9
            E+S+LC
Sbjct: 3397 EFSVLC 3402
>NP_004095
          Length = 2511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SSAEYSI 7
           SSAEY++
Sbjct: 730 SSAEYNV 736
>NP_057613
          Length = 1188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SSAEYSIL 8
          S+A+YS+L
Sbjct: 74 STAKYSVL 81
>NP_004842
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SAEYSILC 9
           + EY ILC
Sbjct: 310 AGEYIILC 317
>NP_055722
          Length = 1578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    SAEYSILC 9
            SAE S LC
Sbjct: 1290 SAEKSFLC 1297
>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    SSAEYSILC 9
            +SA+Y ++C
Sbjct: 6206 TSAKYRLVC 6214
>NP_001258934
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   SAEYSILC 9
           S EY ++C
Sbjct: 279 STEYCLIC 286
>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    SSAEYSILC 9
            +SA+Y ++C
Sbjct: 5279 TSAKYRLVC 5287
>NP_056379
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EYSILC 9
           E+SILC
Sbjct: 334 EHSILC 339
>NP_003449
          Length = 3926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    SSAEYS 6
            SSAEYS
Sbjct: 3701 SSAEYS 3706
>NP_663622
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AEYSILC 9
           A+YSI C
Sbjct: 104 ADYSIKC 110
>NP_001073922
          Length = 2190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4    EYSILC 9
            EY++LC
Sbjct: 2146 EYALLC 2151
>NP_001036009
          Length = 1624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    SAEYSILC 9
            +AEY  LC
Sbjct: 1228 TAEYQSLC 1235
>NP_115823
          Length = 2809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SAEYSILC 9
           SAE+  LC
Sbjct: 663 SAEFQALC 670
>NP_001036010
          Length = 1557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    SAEYSILC 9
            +AEY  LC
Sbjct: 1161 TAEYQSLC 1168
>NP_003564
          Length = 1587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    SAEYSILC 9
            +AEY  LC
Sbjct: 1191 TAEYQSLC 1198
>NP_839947
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   SAEYSILC 9
           S EY ++C
Sbjct: 297 STEYCLIC 304
>XP_006723382
          Length = 5027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4    EYSILC 9
            E+S+LC
Sbjct: 3397 EFSVLC 3402
>XP_006723381
          Length = 5031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4    EYSILC 9
            E+S+LC
Sbjct: 3396 EFSVLC 3401
>XP_006723380
          Length = 5032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4    EYSILC 9
            E+S+LC
Sbjct: 3397 EFSVLC 3402
>XP_006722988
          Length = 2818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SAEYSILC 9
           SAE+  LC
Sbjct: 672 SAEFQALC 679
>XP_006719899
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SSAEYSIL 8
          S+A+YS+L
Sbjct: 34 STAKYSVL 41
>XP_006719898
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SSAEYSIL 8
          S+A+YS+L
Sbjct: 34 STAKYSVL 41
>XP_006719897
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SSAEYSIL 8
          S+A+YS+L
Sbjct: 34 STAKYSVL 41
>XP_006719895
          Length = 1082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SSAEYSIL 8
          S+A+YS+L
Sbjct: 34 STAKYSVL 41
>XP_005266476
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SSAEYSIL 8
          S+A+YS+L
Sbjct: 34 STAKYSVL 41
>XP_005271774
          Length = 443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 5/6 (83%)

Query: 4  EYSILC 9
          EY +LC
Sbjct: 9  EYGVLC 14
>XP_005271772
          Length = 884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 5/6 (83%)

Query: 4  EYSILC 9
          EY +LC
Sbjct: 9  EYGVLC 14
>XP_005251161
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AEYSILC 9
           A+YSI C
Sbjct: 104 ADYSIKC 110
>XP_005251160
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AEYSILC 9
           A+YSI C
Sbjct: 104 ADYSIKC 110
>XP_005251159
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AEYSILC 9
           A+YSI C
Sbjct: 104 ADYSIKC 110
>XP_005263256
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    EYSILC 9
            E+SILC
Sbjct: 1023 EHSILC 1028
>XP_006713443
          Length = 3970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    SSAEYS 6
            SSAEYS
Sbjct: 3745 SSAEYS 3750
>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    SSAEYSILC 9
            +SA+Y ++C
Sbjct: 6207 TSAKYRLVC 6215
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    SSAEYSILC 9
            +SA+Y ++C
Sbjct: 6207 TSAKYRLVC 6215
>NP_001103447
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    EYSILC 9
            E+SILC
Sbjct: 1023 EHSILC 1028
>NP_001138560
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AEYSILC 9
           A+YSI C
Sbjct: 104 ADYSIKC 110
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    SSAEYSILC 9
            +SA+Y ++C
Sbjct: 6523 TSAKYRLVC 6531
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.120    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 461,147
Number of extensions: 1670
Number of successful extensions: 74
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package