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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1135
NP_671714                                                              18    1135
XP_006715890                                                           18    1135
XP_005250160                                                           18    1135
XP_005250159                                                           18    1135
NP_653321                                                              16    5631
NP_001092903                                                           16    5631
NP_065885                                                              16    5631
NP_055138                                                              16    5631
NP_114441                                                              16    5631
NP_114440                                                              16    5631
NP_114439                                                              16    5631
NP_002396                                                              16    5631
NP_001159815                                                           16    5631
NP_000288                                                              16    7355
NP_001139784                                                           16    7355
NP_705832                                                              16    7355
NP_054767                                                              16    7355
XP_005256920                                                           16    7355
XP_006720977                                                           16    7355
XP_006720976                                                           16    7355
XP_006720975                                                           16    7355
XP_005255512                                                           16    7355
XP_006720974                                                           16    7355
XP_005255510                                                           16    7355
XP_006720973                                                           16    7355
XP_006720972                                                           16    7355
XP_006720971                                                           16    7355
XP_005255508                                                           16    7355
XP_005255509                                                           16    7355
NP_037379                                                              15    9605
NP_659540                                                              15    9605
NP_776248                                                              15    9605
NP_055986                                                              15    9605
NP_115997                                                              15    9605
NP_065905                                                              15    9605
NP_001257869                                                           15    9605
XP_006724404                                                           15    9605
XP_005261845                                                           15    9605
XP_005261844                                                           15    9605
XP_005261843                                                           15    9605
XP_006722578                                                           15    9605
XP_005266789                                                           15    9605
XP_006722577                                                           15    9605
XP_006722576                                                           15    9605
XP_005266788                                                           15    9605
XP_005266787                                                           15    9605
XP_005255257                                                           15    9605
XP_005255256                                                           15    9605
XP_005255255                                                           15    9605
XP_005255254                                                           15    9605
XP_005255252                                                           15    9605
XP_005264323                                                           15    9605

>NP_005742
          Length = 3907

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRTREQLAV 9
            SR REQLAV
Sbjct: 1907 SRAREQLAV 1915



>NP_671714
          Length = 3899

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRTREQLAV 9
            SR REQLAV
Sbjct: 1907 SRAREQLAV 1915



>XP_006715890
          Length = 3860

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRTREQLAV 9
            SR REQLAV
Sbjct: 1860 SRAREQLAV 1868



>XP_005250160
          Length = 3939

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRTREQLAV 9
            SR REQLAV
Sbjct: 1939 SRAREQLAV 1947



>XP_005250159
          Length = 3952

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRTREQLAV 9
            SR REQLAV
Sbjct: 1939 SRAREQLAV 1947



>NP_653321
          Length = 626

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SRTREQL 7
           +RTREQL
Sbjct: 519 ARTREQL 525



>NP_001092903
          Length = 831

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SRTREQL 7
           +RTREQL
Sbjct: 519 ARTREQL 525



>NP_065885
          Length = 550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RTREQLAV 9
           +T+EQLA+
Sbjct: 363 KTKEQLAI 370



>NP_055138
          Length = 687

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SRTREQLA 8
           SRTR+Q+A
Sbjct: 349 SRTRKQVA 356



>NP_114441
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SRTREQLA 8
           SRTR+Q+A
Sbjct: 349 SRTRKQVA 356



>NP_114440
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SRTREQLA 8
           SRTR+Q+A
Sbjct: 349 SRTRKQVA 356



>NP_114439
          Length = 641

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SRTREQLA 8
           SRTR+Q+A
Sbjct: 349 SRTRKQVA 356



>NP_002396
          Length = 321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SRTREQLAV 9
          SRTREQ  V
Sbjct: 80 SRTREQTFV 88



>NP_001159815
          Length = 307

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SRTREQL 7
          SRTREQ+
Sbjct: 80 SRTREQV 86



>NP_000288
          Length = 968

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SRTREQLA 8
           SRTRE+ A
Sbjct: 396 SRTREETA 403



>NP_001139784
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  RTREQLA 8
          RT+EQLA
Sbjct: 28 RTQEQLA 34



>NP_705832
          Length = 938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  RTREQLA 8
          RT+EQLA
Sbjct: 28 RTQEQLA 34



>NP_054767
          Length = 1049

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 61 RTREQL 66



>XP_005256920
          Length = 943

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  RTREQLA 8
          RT+EQLA
Sbjct: 28 RTQEQLA 34



>XP_006720977
          Length = 1049

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 61 RTREQL 66



>XP_006720976
          Length = 1053

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 61 RTREQL 66



>XP_006720975
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 32 RTREQL 37



>XP_005255512
          Length = 1088

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 50 RTREQL 55



>XP_006720974
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 61 RTREQL 66



>XP_005255510
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 61 RTREQL 66



>XP_006720973
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 61 RTREQL 66



>XP_006720972
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 61 RTREQL 66



>XP_006720971
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 61 RTREQL 66



>XP_005255508
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 61 RTREQL 66



>XP_005255509
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTREQL 7
          RTREQL
Sbjct: 61 RTREQL 66



>NP_037379
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RTREQLAV 9
           RT+ QLAV
Sbjct: 432 RTQSQLAV 439



>NP_659540
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RTREQLAV 9
           RT+ QLAV
Sbjct: 335 RTQSQLAV 342



>NP_776248
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TREQLA 8
           TREQLA
Sbjct: 189 TREQLA 194



>NP_055986
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TREQLA 8
           TREQLA
Sbjct: 870 TREQLA 875



>NP_115997
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SRTREQLAV 9
          +R R+QLAV
Sbjct: 52 ARQRKQLAV 60



>NP_065905
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TREQLAV 9
           +REQLAV
Sbjct: 803 SREQLAV 809



>NP_001257869
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TREQLA 8
           TREQLA
Sbjct: 856 TREQLA 861



>XP_006724404
          Length = 1442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SRTREQLAV 9
          +R R+QLAV
Sbjct: 52 ARQRKQLAV 60



>XP_005261845
          Length = 2568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SRTREQLAV 9
          +R R+QLAV
Sbjct: 52 ARQRKQLAV 60



>XP_005261844
          Length = 2568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SRTREQLAV 9
          +R R+QLAV
Sbjct: 52 ARQRKQLAV 60



>XP_005261843
          Length = 2568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SRTREQLAV 9
          +R R+QLAV
Sbjct: 52 ARQRKQLAV 60



>XP_006722578
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TREQLAV 9
           +REQLAV
Sbjct: 447 SREQLAV 453



>XP_005266789
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TREQLAV 9
           +REQLAV
Sbjct: 803 SREQLAV 809



>XP_006722577
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TREQLAV 9
           +REQLAV
Sbjct: 803 SREQLAV 809



>XP_006722576
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TREQLAV 9
           +REQLAV
Sbjct: 803 SREQLAV 809



>XP_005266788
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TREQLAV 9
           +REQLAV
Sbjct: 779 SREQLAV 785



>XP_005266787
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TREQLAV 9
           +REQLAV
Sbjct: 803 SREQLAV 809



>XP_005255257
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TREQLA 8
           TREQLA
Sbjct: 519 TREQLA 524



>XP_005255256
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TREQLA 8
           TREQLA
Sbjct: 525 TREQLA 530



>XP_005255255
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TREQLA 8
           TREQLA
Sbjct: 696 TREQLA 701



>XP_005255254
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TREQLA 8
           TREQLA
Sbjct: 796 TREQLA 801



>XP_005255252
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TREQLA 8
           TREQLA
Sbjct: 869 TREQLA 874



>XP_005264323
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RTREQLAV 9
           RT+ QLAV
Sbjct: 400 RTQSQLAV 407



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.119    0.275 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 420,369
Number of extensions: 660
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)