Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001032902                                                           16    7355
XP_005258916                                                           16    7355
XP_006723250                                                           16    7355
NP_115512                                                              16    7355
NP_065750                                                              15    9605
NP_002600                                                              15    9605
NP_060404                                                              15    9605
NP_003155                                                              15    9605
NP_663622                                                              15    9605
NP_055160                                                              15    9605
NP_001231595                                                           15    9605
NP_002842                                                              15    9605
NP_001193767                                                           15    9605
XP_005251162                                                           15    9605
XP_005251161                                                           15    9605
XP_005251160                                                           15    9605
XP_005251159                                                           15    9605
XP_006716139                                                           15    9605
XP_005250576                                                           15    9605
XP_005248786                                                           15    9605
XP_005268521                                                           15    9605
XP_005245421                                                           15    9605
XP_006711532                                                           15    9605
XP_005245420                                                           15    9605
NP_001193768                                                           15    9605
NP_001138560                                                           15    9605
>NP_001032902
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SRQSQLQTN 9
           S+ SQLQT+
Sbjct: 213 SQNSQLQTH 221
>XP_005258916
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SRQSQLQTN 9
           S+ SQLQT+
Sbjct: 213 SQNSQLQTH 221
>XP_006723250
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SRQSQLQTN 9
           S+ SQLQT+
Sbjct: 213 SQNSQLQTH 221
>NP_115512
          Length = 626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QSQLQTN 9
           +SQ+QTN
Sbjct: 279 ESQIQTN 285
>NP_065750
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RQSQLQ 7
           RQSQLQ
Sbjct: 187 RQSQLQ 192
>NP_002600
          Length = 1106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QSQLQTN 9
           +SQL+TN
Sbjct: 473 ESQLETN 479
>NP_060404
          Length = 1821

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RQSQLQTN 9
           RQS L+TN
Sbjct: 105 RQSLLRTN 112
>NP_003155
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SRQSQLQTN 9
          +RQ+ +QTN
Sbjct: 73 TRQNGIQTN 81
>NP_663622
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SRQSQLQT 8
           SR+S++QT
Sbjct: 381 SRESKMQT 388
>NP_055160
          Length = 2279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    RQSQLQTN 9
            R+S+++TN
Sbjct: 1771 RESEIETN 1778
>NP_001231595
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SRQSQLQTN 9
          +RQ+ +QTN
Sbjct: 73 TRQNGIQTN 81
>NP_002842
          Length = 2315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RQSQLQTN 9
           R+S LQTN
Sbjct: 670 RESFLQTN 677
>NP_001193767
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RQSQLQTN 9
           R+S LQTN
Sbjct: 670 RESFLQTN 677
>XP_005251162
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SRQSQLQT 8
           SR+S++QT
Sbjct: 276 SRESKMQT 283
>XP_005251161
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SRQSQLQT 8
           SR+S++QT
Sbjct: 381 SRESKMQT 388
>XP_005251160
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SRQSQLQT 8
           SR+S++QT
Sbjct: 381 SRESKMQT 388
>XP_005251159
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SRQSQLQT 8
           SR+S++QT
Sbjct: 381 SRESKMQT 388
>XP_006716139
          Length = 1869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RQSQLQTN 9
           R+S LQTN
Sbjct: 670 RESFLQTN 677
>XP_005250576
          Length = 2308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RQSQLQTN 9
           R+S LQTN
Sbjct: 670 RESFLQTN 677
>XP_005248786
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RQSQLQTN 9
           RQS L+TN
Sbjct: 105 RQSLLRTN 112
>XP_005268521
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QSQLQTN 9
           +SQL+TN
Sbjct: 409 ESQLETN 415
>XP_005245421
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RQSQLQ 7
           RQSQLQ
Sbjct: 187 RQSQLQ 192
>XP_006711532
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RQSQLQ 7
           RQSQLQ
Sbjct: 187 RQSQLQ 192
>XP_005245420
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RQSQLQ 7
           RQSQLQ
Sbjct: 193 RQSQLQ 198
>NP_001193768
          Length = 1448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RQSQLQTN 9
           R+S LQTN
Sbjct: 670 RESFLQTN 677
>NP_001138560
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SRQSQLQT 8
           SR+S++QT
Sbjct: 381 SRESKMQT 388
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.100    0.228 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 358,350
Number of extensions: 729
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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