Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1135
NP_444254                                                              18    1135
NP_444253                                                              18    1135
NP_444255                                                              18    1135
XP_005247551                                                           18    1135
XP_005247550                                                           18    1135
XP_006713712                                                           18    1135
XP_005247549                                                           18    1135
NP_054777                                                              17    3301
NP_004553                                                              15    9605
NP_054642                                                              15    9605
NP_892006                                                              15    9605
NP_001245384                                                           15    9605
NP_001245383                                                           15    9605
NP_001245385                                                           15    9605
NP_149062                                                              15    9605
NP_001239319                                                           15    9605
NP_001239321                                                           15    9605
NP_001239320                                                           15    9605
NP_001239315                                                           15    9605
NP_001239322                                                           15    9605
NP_001239314                                                           15    9605
NP_006049                                                              15    9605
XP_006715488                                                           15    9605
XP_006715487                                                           15    9605
XP_006715486                                                           15    9605
XP_006715485                                                           15    9605
XP_006715484                                                           15    9605
XP_006715483                                                           15    9605
XP_006715482                                                           15    9605
XP_006715481                                                           15    9605
XP_006715480                                                           15    9605
XP_006715479                                                           15    9605
XP_006715478                                                           15    9605
XP_006715477                                                           15    9605
XP_006715476                                                           15    9605
XP_006715475                                                           15    9605
XP_006715474                                                           15    9605
XP_006715473                                                           15    9605
XP_006715472                                                           15    9605
XP_006715471                                                           15    9605
XP_006715470                                                           15    9605
XP_006714815                                                           15    9605
XP_006714814                                                           15    9605
XP_005268412                                                           15    9605
>NP_444256
          Length = 1794

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRQAQVTLT 9
            SRQAQV LT
Sbjct: 1249 SRQAQVNLT 1257
>NP_444254
          Length = 1845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRQAQVTLT 9
            SRQAQV LT
Sbjct: 1249 SRQAQVNLT 1257
>NP_444253
          Length = 1914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRQAQVTLT 9
            SRQAQV LT
Sbjct: 1318 SRQAQVNLT 1326
>NP_444255
          Length = 1863

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRQAQVTLT 9
            SRQAQV LT
Sbjct: 1318 SRQAQVNLT 1326
>XP_005247551
          Length = 1855

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRQAQVTLT 9
            SRQAQV LT
Sbjct: 1259 SRQAQVNLT 1267
>XP_005247550
          Length = 1856

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRQAQVTLT 9
            SRQAQV LT
Sbjct: 1328 SRQAQVNLT 1336
>XP_006713712
          Length = 1923

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRQAQVTLT 9
            SRQAQV LT
Sbjct: 1328 SRQAQVNLT 1336
>XP_005247549
          Length = 1924

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SRQAQVTLT 9
            SRQAQV LT
Sbjct: 1328 SRQAQVNLT 1336
>NP_054777
          Length = 423

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   RQAQVTL 8
           RQAQVTL
Sbjct: 330 RQAQVTL 336
>NP_004553
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RQAQVTLT 9
           RQA +TLT
Sbjct: 170 RQATLTLT 177
>NP_054642
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RQAQVTLT 9
           RQA +TLT
Sbjct: 170 RQATLTLT 177
>NP_892006
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5650 QAQATLT 5656
>NP_001245384
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>NP_001245383
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>NP_001245385
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>NP_149062
          Length = 8749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5579 QAQATLT 5585
>NP_001239319
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>NP_001239321
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>NP_001239320
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>NP_001239315
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 445 QAQVTLS 451
>NP_001239322
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>NP_001239314
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>NP_006049
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>XP_006715488
          Length = 8721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715487
          Length = 8744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715486
          Length = 8758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715485
          Length = 8793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5604 QAQATLT 5610
>XP_006715484
          Length = 8794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5605 QAQATLT 5611
>XP_006715483
          Length = 8795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715482
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5650 QAQATLT 5656
>XP_006715481
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5610 QAQATLT 5616
>XP_006715480
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715479
          Length = 8804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715478
          Length = 8809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715477
          Length = 8822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5633 QAQATLT 5639
>XP_006715476
          Length = 8823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715475
          Length = 8827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715474
          Length = 8829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5640 QAQATLT 5646
>XP_006715473
          Length = 8832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715472
          Length = 8839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5650 QAQATLT 5656
>XP_006715471
          Length = 8842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006715470
          Length = 8846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QAQVTLT 9
            QAQ TLT
Sbjct: 5657 QAQATLT 5663
>XP_006714815
          Length = 571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>XP_006714814
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
>XP_005268412
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QAQVTLT 9
           QAQVTL+
Sbjct: 498 QAQVTLS 504
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.109    0.250 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 270,370
Number of extensions: 273
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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