Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001165599                                                           16    5631
NP_757366                                                              16    5631
XP_005254400                                                           16    5631
XP_005254399                                                           16    5631
NP_542376                                                              16    7355
NP_004361                                                              16    7355
XP_006715397                                                           16    7355
NP_065896                                                              15    9605
NP_001020109                                                           15    9605
NP_001269793                                                           15    9605
NP_110434                                                              15    9605
NP_001020110                                                           15    9605
XP_006719582                                                           15    9605
XP_005253643                                                           15    9605
XP_005253642                                                           15    9605
XP_006719581                                                           15    9605
XP_006719580                                                           15    9605
XP_005253640                                                           15    9605
XP_006719579                                                           15    9605
XP_005253639                                                           15    9605
>NP_001165599
          Length = 1331

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SRKSAQFQ 8
          SRKSA+F+
Sbjct: 10 SRKSAKFR 17
>NP_757366
          Length = 1332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SRKSAQFQ 8
          SRKSA+F+
Sbjct: 10 SRKSAKFR 17
>XP_005254400
          Length = 1378

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SRKSAQFQ 8
          SRKSA+F+
Sbjct: 57 SRKSAKFR 64
>XP_005254399
          Length = 1379

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SRKSAQFQ 8
          SRKSA+F+
Sbjct: 57 SRKSAKFR 64
>NP_542376
          Length = 1899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RKSAQFQM 9
            RKSA FQ+
Sbjct: 1532 RKSAAFQI 1539
>NP_004361
          Length = 3063

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RKSAQFQM 9
            RKSA FQ+
Sbjct: 2696 RKSAAFQI 2703
>XP_006715397
          Length = 2972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RKSAQFQM 9
            RKSA FQ+
Sbjct: 2605 RKSAAFQI 2612
>NP_065896
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SRKSAQF 7
           SRK AQF
Sbjct: 254 SRKMAQF 260
>NP_001020109
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRKSAQFQM 9
           SRK+  F+M
Sbjct: 115 SRKAGSFEM 123
>NP_001269793
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRKSAQFQM 9
           SRK+  F+M
Sbjct: 122 SRKAGSFEM 130
>NP_110434
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRKSAQFQM 9
           SRK+  F+M
Sbjct: 122 SRKAGSFEM 130
>NP_001020110
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRKSAQFQM 9
           SRK+  F+M
Sbjct: 118 SRKAGSFEM 126
>XP_006719582
          Length = 1295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SRKSAQF 7
           SRK AQF
Sbjct: 254 SRKMAQF 260
>XP_005253643
          Length = 1331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SRKSAQF 7
           SRK AQF
Sbjct: 188 SRKMAQF 194
>XP_005253642
          Length = 1343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SRKSAQF 7
           SRK AQF
Sbjct: 254 SRKMAQF 260
>XP_006719581
          Length = 1380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SRKSAQF 7
           SRK AQF
Sbjct: 254 SRKMAQF 260
>XP_006719580
          Length = 1381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SRKSAQF 7
           SRK AQF
Sbjct: 254 SRKMAQF 260
>XP_005253640
          Length = 1397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SRKSAQF 7
           SRK AQF
Sbjct: 254 SRKMAQF 260
>XP_006719579
          Length = 1397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SRKSAQF 7
           SRK AQF
Sbjct: 254 SRKMAQF 260
>XP_005253639
          Length = 1397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SRKSAQF 7
           SRK AQF
Sbjct: 254 SRKMAQF 260
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.112    0.272 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 295,073
Number of extensions: 285
Number of successful extensions: 20
Number of sequences better than 10000.0: 20
Number of HSP's gapped: 20
Number of HSP's successfully gapped: 20
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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