Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001121619                                                           18    1482
NP_000258                                                              18    1482
NP_001035957                                                           18    1482
XP_006721991                                                           18    1482
XP_006721990                                                           18    1482
XP_006721989                                                           18    1482
XP_005258041                                                           18    1482
XP_006721988                                                           18    1482
XP_006721987                                                           18    1482
XP_006721986                                                           18    1482
XP_005258040                                                           18    1482
XP_006721985                                                           18    1482
XP_005276195                                                           16    5631
XP_005277559                                                           16    5631
XP_006710144                                                           16    5631
NP_000538                                                              16    7355
NP_783653                                                              16    7355
NP_006648                                                              16    7355
NP_998770                                                              16    7355
NP_996848                                                              16    7355
XP_006724024                                                           16    7355
XP_006716616                                                           16    7355
XP_005264762                                                           16    7355
XP_005264761                                                           16    7355
XP_005264759                                                           16    7355
XP_005264758                                                           16    7355
XP_005264757                                                           16    7355
XP_005264756                                                           16    7355
XP_005264755                                                           16    7355
NP_783652                                                              16    7355
NP_001193674                                                           16    7355
NP_783650                                                              16    7355
NP_001193673                                                           16    7355
NP_078801                                                              15    9605
XP_006711877                                                           15    9605
XP_005273321                                                           15    9605
XP_005273318                                                           15    9605
XP_005273317                                                           15    9605
>NP_001121619
          Length = 593

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>NP_000258
          Length = 2818

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>NP_001035957
          Length = 2839

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>XP_006721991
          Length = 1632

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>XP_006721990
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>XP_006721989
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>XP_005258041
          Length = 2836

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>XP_006721988
          Length = 2846

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>XP_006721987
          Length = 2849

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>XP_006721986
          Length = 2854

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 142 SRISTRLQE 150
>XP_005258040
          Length = 2857

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>XP_006721985
          Length = 2867

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           SRIST LQE
Sbjct: 155 SRISTRLQE 163
>XP_005276195
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           +R ST+LQE
Sbjct: 123 ARYSTLLQE 131
>XP_005277559
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           +R ST+LQE
Sbjct: 123 ARYSTLLQE 131
>XP_006710144
          Length = 564

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SRISTMLQE 9
           +R ST+LQE
Sbjct: 123 ARYSTLLQE 131
>NP_000538
          Length = 933

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 37 SRVSSVLEE 45
>NP_783653
          Length = 760

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 37 SRVSSVLEE 45
>NP_006648
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RISTMLQE 9
           R+S++LQE
Sbjct: 517 RVSSLLQE 524
>NP_998770
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SRISTMLQ 8
           SR+ST++Q
Sbjct: 462 SRLSTLIQ 469
>NP_996848
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RISTMLQE 9
           R+S++LQE
Sbjct: 517 RVSSLLQE 524
>XP_006724024
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RISTMLQE 9
           R+S++LQE
Sbjct: 560 RVSSLLQE 567
>XP_006716616
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SRISTMLQ 8
           SR+ST++Q
Sbjct: 462 SRLSTLIQ 469
>XP_005264762
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 49 SRVSSVLEE 57
>XP_005264761
          Length = 844

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 49 SRVSSVLEE 57
>XP_005264759
          Length = 888

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 49 SRVSSVLEE 57
>XP_005264758
          Length = 901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 49 SRVSSVLEE 57
>XP_005264757
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 49 SRVSSVLEE 57
>XP_005264756
          Length = 945

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 49 SRVSSVLEE 57
>XP_005264755
          Length = 947

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 49 SRVSSVLEE 57
>NP_783652
          Length = 889

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 37 SRVSSVLEE 45
>NP_001193674
          Length = 876

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 37 SRVSSVLEE 45
>NP_783650
          Length = 876

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 37 SRVSSVLEE 45
>NP_001193673
          Length = 933

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SRISTMLQE 9
          SR+S++L+E
Sbjct: 37 SRVSSVLEE 45
>NP_078801
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   STMLQE 9
           STMLQE
Sbjct: 167 STMLQE 172
>XP_006711877
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   STMLQE 9
           STMLQE
Sbjct: 167 STMLQE 172
>XP_005273321
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   STMLQE 9
           STMLQE
Sbjct: 167 STMLQE 172
>XP_005273318
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   STMLQE 9
           STMLQE
Sbjct: 167 STMLQE 172
>XP_005273317
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   STMLQE 9
           STMLQE
Sbjct: 167 STMLQE 172
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.117    0.261 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 367,437
Number of extensions: 618
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package