Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005912                                                              20     509
XP_005248577                                                           20     509
XP_005248576                                                           20     509
NP_001025035                                                           17    2528
NP_001138548                                                           17    2528
NP_061936                                                              17    2528
XP_006712055                                                           17    2528
XP_006712054                                                           17    2528
XP_005264324                                                           17    2528
NP_001167573                                                           17    3301
NP_001167572                                                           17    3301
NP_085044                                                              17    3301
NP_001073890                                                           17    3301
XP_006722755                                                           17    3301
NP_065769                                                              17    4312
NP_114095                                                              17    4312
XP_006721134                                                           17    4312
XP_005255507                                                           17    4312
XP_006714119                                                           17    4312
NP_001186978                                                           16    5631
NP_077005                                                              16    5631
NP_001245212                                                           16    5631
NP_064592                                                              16    7355
NP_114037                                                              16    7355
NP_114036                                                              16    7355
NP_001264992                                                           16    7355
NP_061732                                                              16    7355
XP_006722588                                                           16    7355
XP_005252384                                                           16    7355
XP_005252025                                                           16    7355
NP_002826                                                              15    9605
NP_000121                                                              15    9605
NP_001202                                                              15    9605
NP_001229243                                                           15    9605
NP_004712                                                              15    9605
NP_001244904                                                           15    9605
NP_001229246                                                           15    9605
NP_079414                                                              15    9605
NP_060907                                                              15    9605
NP_060823                                                              15    9605
NP_932095                                                              15    9605
NP_872363                                                              15    9605
XP_005267890                                                           15    9605
XP_005266602                                                           15    9605
XP_005271570                                                           15    9605
XP_005271569                                                           15    9605
XP_006718878                                                           15    9605
XP_005271568                                                           15    9605
XP_005252145                                                           15    9605
XP_006717237                                                           15    9605
XP_005252143                                                           15    9605
XP_005251949                                                           15    9605
XP_005251948                                                           15    9605
XP_005251946                                                           15    9605
XP_006717100                                                           15    9605
XP_005251945                                                           15    9605
XP_006717099                                                           15    9605
XP_005251944                                                           15    9605
XP_005251943                                                           15    9605
XP_006716136                                                           15    9605
XP_005248148                                                           15    9605
XP_005248147                                                           15    9605
XP_005248146                                                           15    9605
XP_005248145                                                           15    9605
XP_005248142                                                           15    9605
XP_005248141                                                           15    9605
XP_005248140                                                           15    9605
XP_005248139                                                           15    9605
>NP_005912
          Length = 1512

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRIKAPSHN 9
           SRIKAPS N
Sbjct: 398 SRIKAPSRN 406
>XP_005248577
          Length = 1349

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRIKAPSHN 9
           SRIKAPS N
Sbjct: 235 SRIKAPSRN 243
>XP_005248576
          Length = 1375

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SRIKAPSHN 9
           SRIKAPS N
Sbjct: 261 SRIKAPSRN 269
>NP_001025035
          Length = 1200

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IKAPSHN 9
           +KAP+HN
Sbjct: 358 LKAPTHN 364
>NP_001138548
          Length = 923

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SRIKAPSH 8
           S+ KAPSH
Sbjct: 763 SKAKAPSH 770
>NP_061936
          Length = 981

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SRIKAPSH 8
           S+ KAPSH
Sbjct: 821 SKAKAPSH 828
>XP_006712055
          Length = 913

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SRIKAPSH 8
           S+ KAPSH
Sbjct: 753 SKAKAPSH 760
>XP_006712054
          Length = 934

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SRIKAPSH 8
           S+ KAPSH
Sbjct: 774 SKAKAPSH 781
>XP_005264324
          Length = 992

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SRIKAPSH 8
           S+ KAPSH
Sbjct: 832 SKAKAPSH 839
>NP_001167573
          Length = 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SRIKAPSH 8
          SR++AP+H
Sbjct: 82 SRLEAPAH 89
>NP_001167572
          Length = 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SRIKAPSH 8
          SR++AP+H
Sbjct: 82 SRLEAPAH 89
>NP_085044
          Length = 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SRIKAPSH 8
          SR++AP+H
Sbjct: 82 SRLEAPAH 89
>NP_001073890
          Length = 1703

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    RIKAPSHN 9
            R+K PSH+
Sbjct: 1416 RVKLPSHS 1423
>XP_006722755
          Length = 1722

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    RIKAPSHN 9
            R+K PSH+
Sbjct: 1416 RVKLPSHS 1423
>NP_065769
          Length = 1352

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    IKAPSH 8
            +KAPSH
Sbjct: 1006 VKAPSH 1011
>NP_114095
          Length = 1142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IKAPSHN 9
           +K PSHN
Sbjct: 139 LKQPSHN 145
>XP_006721134
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   IKAPSH 8
           +KAPSH
Sbjct: 743 VKAPSH 748
>XP_005255507
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   IKAPSH 8
           +KAPSH
Sbjct: 743 VKAPSH 748
>XP_006714119
          Length = 1142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IKAPSHN 9
           +K PSHN
Sbjct: 139 LKQPSHN 145
>NP_001186978
          Length = 2715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    RIKAPSHN 9
            +++APSH+
Sbjct: 2570 KLRAPSHH 2577
>NP_077005
          Length = 432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SRIKAPSH 8
           SRI AP H
Sbjct: 159 SRIPAPRH 166
>NP_001245212
          Length = 315

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RIKAPSHN 9
           R +APSH+
Sbjct: 265 RYRAPSHD 272
>NP_064592
          Length = 1561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    KAPSHN 9
            K PSHN
Sbjct: 1085 KLPSHN 1090
>NP_114037
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RIKAPSHN 9
           R +AP+HN
Sbjct: 202 REEAPAHN 209
>NP_114036
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RIKAPSHN 9
           R +AP+HN
Sbjct: 202 REEAPAHN 209
>NP_001264992
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SRIKAPSH 8
           SR+ AP H
Sbjct: 597 SRVPAPHH 604
>NP_061732
          Length = 950

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RIKAPSHN 9
           R +AP+HN
Sbjct: 202 REEAPAHN 209
>XP_006722588
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SRIKAPSH 8
           SR+ AP H
Sbjct: 597 SRVPAPHH 604
>XP_005252384
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   KAPSHN 9
           K PSHN
Sbjct: 365 KLPSHN 370
>XP_005252025
          Length = 826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SRIKAP 6
           SRIKAP
Sbjct: 491 SRIKAP 496
>NP_002826
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3  IKAPSHN 9
          +K+P HN
Sbjct: 17 MKSPDHN 23
>NP_000121
          Length = 2224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4   KAPSH 8
           KAPSH
Sbjct: 796 KAPSH 800
>NP_001202
          Length = 1050

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IKAPSHN 9
           +KAPS N
Sbjct: 249 LKAPSQN 255
>NP_001229243
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   KAPSHN 9
           K+P+HN
Sbjct: 759 KSPAHN 764
>NP_004712
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   KAPSHN 9
           K+P+HN
Sbjct: 759 KSPAHN 764
>NP_001244904
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  RIKAPSH 8
          +++APSH
Sbjct: 5  QLRAPSH 11
>NP_001229246
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   KAPSHN 9
           K+P+HN
Sbjct: 552 KSPAHN 557
>NP_079414
          Length = 944

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SRIKAPSHN 9
           S  K PSH+
Sbjct: 617 SAFKGPSHS 625
>NP_060907
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4   KAPSH 8
           KAPSH
Sbjct: 336 KAPSH 340
>NP_060823
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   KAPSHN 9
           KAP HN
Sbjct: 211 KAPLHN 216
>NP_932095
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4   KAPSH 8
           KAPSH
Sbjct: 336 KAPSH 340
>NP_872363
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SRIKAPS 7
           SR+K+PS
Sbjct: 993 SRLKSPS 999
>XP_005267890
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   KAPSHN 9
           KAP HN
Sbjct: 211 KAPLHN 216
>XP_005266602
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SRIKAPSHN 9
           S  K PSH+
Sbjct: 595 SAFKGPSHS 603
>XP_005271570
          Length = 1462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SRIKAPS 7
           SR+K+PS
Sbjct: 956 SRLKSPS 962
>XP_005271569
          Length = 1462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SRIKAPS 7
           SR+K+PS
Sbjct: 956 SRLKSPS 962
>XP_006718878
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SRIKAPS 7
           SR+K+PS
Sbjct: 993 SRLKSPS 999
>XP_005271568
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SRIKAPS 7
           SR+K+PS
Sbjct: 993 SRLKSPS 999
>XP_005252145
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4   KAPSH 8
           KAPSH
Sbjct: 161 KAPSH 165
>XP_006717237
          Length = 470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4   KAPSH 8
           KAPSH
Sbjct: 336 KAPSH 340
>XP_005252143
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4   KAPSH 8
           KAPSH
Sbjct: 336 KAPSH 340
>XP_005251949
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  RIKAPSH 8
          +++APSH
Sbjct: 5  QLRAPSH 11
>XP_005251948
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  RIKAPSH 8
          +++APSH
Sbjct: 5  QLRAPSH 11
>XP_005251946
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  RIKAPSH 8
          +++APSH
Sbjct: 5  QLRAPSH 11
>XP_006717100
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  RIKAPSH 8
          +++APSH
Sbjct: 5  QLRAPSH 11
>XP_005251945
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  RIKAPSH 8
          +++APSH
Sbjct: 5  QLRAPSH 11
>XP_006717099
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  RIKAPSH 8
          +++APSH
Sbjct: 5  QLRAPSH 11
>XP_005251944
          Length = 990

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  RIKAPSH 8
          +++APSH
Sbjct: 5  QLRAPSH 11
>XP_005251943
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  RIKAPSH 8
          +++APSH
Sbjct: 5  QLRAPSH 11
>XP_006716136
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3  IKAPSHN 9
          +K+P HN
Sbjct: 17 MKSPDHN 23
>XP_005248148
          Length = 3028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRIKAPSHN 9
           S +K PS+N
Sbjct: 342 SHLKMPSNN 350
>XP_005248147
          Length = 3028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRIKAPSHN 9
           S +K PS+N
Sbjct: 342 SHLKMPSNN 350
>XP_005248146
          Length = 3073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRIKAPSHN 9
           S +K PS+N
Sbjct: 434 SHLKMPSNN 442
>XP_005248145
          Length = 3079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRIKAPSHN 9
           S +K PS+N
Sbjct: 393 SHLKMPSNN 401
>XP_005248142
          Length = 3114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRIKAPSHN 9
           S +K PS+N
Sbjct: 434 SHLKMPSNN 442
>XP_005248141
          Length = 3119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRIKAPSHN 9
           S +K PS+N
Sbjct: 434 SHLKMPSNN 442
>XP_005248140
          Length = 3119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRIKAPSHN 9
           S +K PS+N
Sbjct: 434 SHLKMPSNN 442
>XP_005248139
          Length = 3120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SRIKAPSHN 9
           S +K PS+N
Sbjct: 434 SHLKMPSNN 442
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.117    0.335 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 780,274
Number of extensions: 881
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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