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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055365                                                              18    1135
NP_775834                                                              17    4312
XP_006715090                                                           17    4312
XP_006715089                                                           17    4312
XP_006715088                                                           17    4312
XP_005249008                                                           17    4312
NP_438170                                                              16    5631
NP_077015                                                              16    5631
NP_056107                                                              16    5631
NP_001171725                                                           16    5631
NP_001244899                                                           16    5631
NP_001127922                                                           16    7355
NP_057360                                                              16    7355
NP_690877                                                              16    7355
NP_079520                                                              16    7355
NP_878915                                                              16    7355
NP_733794                                                              16    7355
NP_001186193                                                           16    7355
XP_006712845                                                           16    7355
XP_005264086                                                           16    7355
XP_005264084                                                           16    7355
XP_005264083                                                           16    7355
XP_006712844                                                           16    7355
XP_005264082                                                           16    7355
XP_005264081                                                           16    7355
XP_005264080                                                           16    7355
XP_006712843                                                           16    7355
XP_005264079                                                           16    7355
NP_001159396                                                           15    9605
NP_004089                                                              15    9605
XP_005264260                                                           15    9605
NP_004088                                                              15    9605

>NP_055365
          Length = 1032

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           SQSLI KDQ
Sbjct: 410 SQSLIEKDQ 418



>NP_775834
          Length = 508

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           S SLIAKD+
Sbjct: 492 SPSLIAKDK 500



>XP_006715090
          Length = 352

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           S SLIAKD+
Sbjct: 336 SPSLIAKDK 344



>XP_006715089
          Length = 445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           S SLIAKD+
Sbjct: 429 SPSLIAKDK 437



>XP_006715088
          Length = 445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           S SLIAKD+
Sbjct: 429 SPSLIAKDK 437



>XP_005249008
          Length = 499

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           S SLIAKD+
Sbjct: 483 SPSLIAKDK 491



>NP_438170
          Length = 434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQSLIAKD 8
           SQSL+ KD
Sbjct: 139 SQSLVEKD 146



>NP_077015
          Length = 1004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQSLIAKD 8
           SQSL+ KD
Sbjct: 376 SQSLVEKD 383



>NP_056107
          Length = 1104

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           +Q LIAKD+
Sbjct: 656 AQDLIAKDR 664



>NP_001171725
          Length = 1114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           +Q LIAKD+
Sbjct: 666 AQDLIAKDR 674



>NP_001244899
          Length = 740

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQSLIAKD 8
           SQSL+ KD
Sbjct: 376 SQSLVEKD 383



>NP_001127922
          Length = 435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SQSLIAKD 8
          S SL+AKD
Sbjct: 50 SASLVAKD 57



>NP_057360
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSLIAKDQ 9
           QSL+ KDQ
Sbjct: 326 QSLLHKDQ 333



>NP_690877
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SQSLIAKD 8
          S SL+AKD
Sbjct: 50 SASLVAKD 57



>NP_079520
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 526 NRQLVAKDQ 534



>NP_878915
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 526 NRQLVAKDQ 534



>NP_733794
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSLIAKDQ 9
           QSL+ KDQ
Sbjct: 266 QSLLHKDQ 273



>NP_001186193
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSLIAKDQ 9
           QSL+ KDQ
Sbjct: 266 QSLLHKDQ 273



>XP_006712845
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 526 NRQLVAKDQ 534



>XP_005264086
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 526 NRQLVAKDQ 534



>XP_005264084
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 526 NRQLVAKDQ 534



>XP_005264083
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 526 NRQLVAKDQ 534



>XP_006712844
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 526 NRQLVAKDQ 534



>XP_005264082
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 526 NRQLVAKDQ 534



>XP_005264081
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 526 NRQLVAKDQ 534



>XP_005264080
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 526 NRQLVAKDQ 534



>XP_006712843
          Length = 891

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 726 NRQLVAKDQ 734



>XP_005264079
          Length = 893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSLIAKDQ 9
           ++ L+AKDQ
Sbjct: 721 NRQLVAKDQ 729



>NP_001159396
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QSLIAKD 8
          +SL+AKD
Sbjct: 13 ESLVAKD 19



>NP_004089
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QSLIAKD 8
          +SL+AKD
Sbjct: 13 ESLVAKD 19



>XP_005264260
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QSLIAKD 8
          +SL+AKD
Sbjct: 46 ESLVAKD 52



>NP_004088
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QSLIAKD 8
          +SL+AKD
Sbjct: 46 ESLVAKD 52



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.112    0.251 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 337,651
Number of extensions: 346
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)