Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           20     390
NP_036462                                                              20     390
NP_001243397                                                           20     390
XP_005269721                                                           20     390
NP_001121113                                                           17    3301
NP_001017402                                                           17    3301
NP_000219                                                              17    3301
XP_005273181                                                           17    3301
NP_114437                                                              16    7355
XP_006726265                                                           16    7355
XP_006726264                                                           16    7355
XP_006726228                                                           16    7355
XP_006726227                                                           16    7355
XP_005277331                                                           16    7355
XP_006726127                                                           16    7355
XP_006726126                                                           16    7355
XP_006726028                                                           16    7355
XP_006726027                                                           16    7355
XP_006725940                                                           16    7355
XP_006725939                                                           16    7355
XP_005259193                                                           16    7355
XP_005259192                                                           16    7355
XP_005277373                                                           16    7355
XP_005277372                                                           16    7355
XP_005277141                                                           16    7355
XP_005277142                                                           16    7355
XP_005278344                                                           16    7355
XP_005278345                                                           16    7355
XP_005252887                                                           16    7355
XP_005252886                                                           16    7355
NP_001004                                                              16    7355
NP_055870                                                              16    7355
NP_001186732                                                           15    9605
NP_077298                                                              15    9605
NP_001277150                                                           15    9605
NP_001277151                                                           15    9605
NP_000895                                                              15    9605
NP_057133                                                              15    9605
NP_001077054                                                           15    9605
NP_004694                                                              15    9605
XP_005267778                                                           15    9605
XP_005249208                                                           15    9605
XP_006715164                                                           15    9605
XP_005249207                                                           15    9605
XP_006715163                                                           15    9605
XP_005249205                                                           15    9605
XP_005249206                                                           15    9605
XP_006712165                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQRLQTQVA 9
            SQRLQTQ+A
Sbjct: 1618 SQRLQTQIA 1626
>NP_036462
          Length = 2073

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQRLQTQVA 9
            SQRLQTQ+A
Sbjct: 1910 SQRLQTQIA 1918
>NP_001243397
          Length = 1890

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQRLQTQVA 9
            SQRLQTQ+A
Sbjct: 1727 SQRLQTQIA 1735
>XP_005269721
          Length = 2073

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQRLQTQVA 9
            SQRLQTQ+A
Sbjct: 1910 SQRLQTQIA 1918
>NP_001121113
          Length = 1172

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SQRLQTQVA 9
           +QRL+TQV+
Sbjct: 867 AQRLETQVS 875
>NP_001017402
          Length = 1172

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SQRLQTQVA 9
           +QRL+TQV+
Sbjct: 867 AQRLETQVS 875
>NP_000219
          Length = 1172

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SQRLQTQVA 9
           +QRL+TQV+
Sbjct: 867 AQRLETQVS 875
>XP_005273181
          Length = 1172

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SQRLQTQVA 9
           +QRL+TQV+
Sbjct: 867 AQRLETQVS 875
>NP_114437
          Length = 1053

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           QRLQ+QV
Sbjct: 675 QRLQSQV 681
>XP_006726265
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_006726264
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_006726228
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_006726227
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_005277331
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_006726127
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_006726126
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_006726028
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_006726027
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_006725940
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_006725939
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_005259193
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_005259192
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_005277373
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_005277372
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_005277141
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_005277142
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_005278344
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_005278345
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>XP_005252887
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 226 KRLQTQV 232
>XP_005252886
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 317 KRLQTQV 323
>NP_001004
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 108 RRLQTQV 114
>NP_055870
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QRLQTQV 8
           +RLQTQV
Sbjct: 375 KRLQTQV 381
>NP_001186732
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QRLQTQVA 9
          +RL+TQV+
Sbjct: 16 ERLETQVS 23
>NP_077298
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QRLQTQVA 9
          +RL+TQV+
Sbjct: 22 ERLETQVS 29
>NP_001277150
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQRLQT 6
           SQRLQT
Sbjct: 209 SQRLQT 214
>NP_001277151
          Length = 193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQRLQT 6
           SQRLQT
Sbjct: 171 SQRLQT 176
>NP_000895
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQRLQT 6
           SQRLQT
Sbjct: 209 SQRLQT 214
>NP_057133
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SQRLQTQV 8
           +QRL TQ+
Sbjct: 188 NQRLNTQI 195
>NP_001077054
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SQRLQTQV 8
           +QRLQT++
Sbjct: 771 AQRLQTEL 778
>NP_004694
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SQRLQTQV 8
           +QRLQT++
Sbjct: 804 AQRLQTEL 811
>XP_005267778
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SQRLQTQV 8
           +QRL TQ+
Sbjct: 188 NQRLNTQI 195
>XP_005249208
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQRLQT 6
           SQRLQT
Sbjct: 209 SQRLQT 214
>XP_006715164
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQRLQT 6
           SQRLQT
Sbjct: 209 SQRLQT 214
>XP_005249207
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQRLQT 6
           SQRLQT
Sbjct: 209 SQRLQT 214
>XP_006715163
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQRLQT 6
           SQRLQT
Sbjct: 209 SQRLQT 214
>XP_005249205
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQRLQT 6
           SQRLQT
Sbjct: 209 SQRLQT 214
>XP_005249206
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQRLQT 6
           SQRLQT
Sbjct: 209 SQRLQT 214
>XP_006712165
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QRLQTQVA 9
          +RL+TQV+
Sbjct: 22 ERLETQVS 29
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.111    0.252 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 343,571
Number of extensions: 566
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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