Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1935
NP_001035957                                                           18    1935
XP_006721991                                                           18    1935
XP_006721990                                                           18    1935
XP_006721989                                                           18    1935
XP_005258041                                                           18    1935
XP_006721988                                                           18    1935
XP_006721987                                                           18    1935
XP_006721986                                                           18    1935
XP_005258040                                                           18    1935
XP_006721985                                                           18    1935
NP_001092879                                                           17    4312
XP_005273927                                                           17    4312
XP_005273926                                                           17    4312
XP_005273925                                                           17    4312
XP_005273924                                                           17    4312
XP_006718549                                                           17    4312
NP_060236                                                              16    7355
NP_057308                                                              16    7355
NP_001073312                                                           16    7355
NP_001096127                                                           16    7355
NP_005157                                                              16    7355
NP_001019978                                                           16    7355
XP_005259656                                                           16    7355
XP_005267072                                                           16    7355
XP_006710775                                                           16    7355
XP_005263536                                                           16    7355
NP_277052                                                              15    9605
NP_001278062                                                           15    9605
NP_037398                                                              15    9605
NP_001120856                                                           15    9605
NP_055951                                                              15    9605
NP_006369                                                              15    9605
NP_001264262                                                           15    9605
XP_003959998                                                           15    9605
XP_005269774                                                           15    9605
XP_006717868                                                           15    9605
XP_005251711                                                           15    9605
XP_006716993                                                           15    9605
XP_006716992                                                           15    9605
XP_006716991                                                           15    9605
XP_006716990                                                           15    9605
XP_006716989                                                           15    9605
XP_006716988                                                           15    9605
XP_006716987                                                           15    9605
XP_006716986                                                           15    9605
XP_006716985                                                           15    9605
XP_005250117                                                           15    9605
XP_005265032                                                           15    9605
XP_005265031                                                           15    9605
XP_005265030                                                           15    9605
NP_003583                                                              15    9605
>NP_000258
          Length = 2818

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1234 SQWDELARV 1242
>NP_001035957
          Length = 2839

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1234 SQWDELARV 1242
>XP_006721991
          Length = 1632

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1244 SQWDELARV 1252
>XP_006721990
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1244 SQWDELARV 1252
>XP_006721989
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1244 SQWDELARV 1252
>XP_005258041
          Length = 2836

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1234 SQWDELARV 1242
>XP_006721988
          Length = 2846

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1244 SQWDELARV 1252
>XP_006721987
          Length = 2849

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1244 SQWDELARV 1252
>XP_006721986
          Length = 2854

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1231 SQWDELARV 1239
>XP_005258040
          Length = 2857

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1234 SQWDELARV 1242
>XP_006721985
          Length = 2867

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQRDELARV 9
            SQ DELARV
Sbjct: 1244 SQWDELARV 1252
>NP_001092879
          Length = 1523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SQRDELAR 8
            +QRDEL R
Sbjct: 1476 NQRDELVR 1483
>XP_005273927
          Length = 777

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQRDELAR 8
           +QRDEL R
Sbjct: 730 NQRDELVR 737
>XP_005273926
          Length = 835

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQRDELAR 8
           +QRDEL R
Sbjct: 788 NQRDELVR 795
>XP_005273925
          Length = 935

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQRDELAR 8
           +QRDEL R
Sbjct: 888 NQRDELVR 895
>XP_005273924
          Length = 993

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQRDELAR 8
           +QRDEL R
Sbjct: 946 NQRDELVR 953
>XP_006718549
          Length = 1535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SQRDELAR 8
            +QRDEL R
Sbjct: 1488 NQRDELVR 1495
>NP_060236
          Length = 1166

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RDELAR 8
           RDELAR
Sbjct: 197 RDELAR 202
>NP_057308
          Length = 595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQRDELARV 9
           ++RDELA V
Sbjct: 369 AERDELAGV 377
>NP_001073312
          Length = 1759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RDELAR 8
           RDELAR
Sbjct: 197 RDELAR 202
>NP_001096127
          Length = 936

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQRDELAR 8
           SQR +LAR
Sbjct: 452 SQRSQLAR 459
>NP_005157
          Length = 650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QRDELA 7
           QRDELA
Sbjct: 566 QRDELA 571
>NP_001019978
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QRDELA 7
           QRDELA
Sbjct: 567 QRDELA 572
>XP_005259656
          Length = 1373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    QRDELA 7
            QRDELA
Sbjct: 1286 QRDELA 1291
>XP_005267072
          Length = 588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQRDELARV 9
           ++RDELA V
Sbjct: 362 AERDELAGV 370
>XP_006710775
          Length = 1759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RDELAR 8
           RDELAR
Sbjct: 197 RDELAR 202
>XP_005263536
          Length = 1783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RDELAR 8
           RDELAR
Sbjct: 221 RDELAR 226
>NP_277052
          Length = 1731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RDELARV 9
            R+ELAR+
Sbjct: 1298 REELARI 1304
>NP_001278062
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SQRDELA 7
           +QRDE+A
Sbjct: 211 NQRDEIA 217
>NP_037398
          Length = 895

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SQRDELA 7
           +QRDE+A
Sbjct: 199 NQRDEIA 205
>NP_001120856
          Length = 895

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SQRDELA 7
           +QRDE+A
Sbjct: 199 NQRDEIA 205
>NP_055951
          Length = 2570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RDELARV 9
            +DELAR+
Sbjct: 1629 QDELARI 1635
>NP_006369
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 577 SQKSNLARV 585
>NP_001264262
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RDELARV 9
           RDE+AR+
Sbjct: 565 RDEIARL 571
>XP_003959998
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RDELARV 9
           RDE+AR+
Sbjct: 287 RDEIARL 293
>XP_005269774
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SQRDELA 7
           +QRDE+A
Sbjct: 211 NQRDEIA 217
>XP_006717868
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SQRDELA 7
           +QRDE+A
Sbjct: 211 NQRDEIA 217
>XP_005251711
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 577 SQKSNLARV 585
>XP_006716993
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 602 SQKSNLARV 610
>XP_006716992
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 602 SQKSNLARV 610
>XP_006716991
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 602 SQKSNLARV 610
>XP_006716990
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 602 SQKSNLARV 610
>XP_006716989
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 602 SQKSNLARV 610
>XP_006716988
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 602 SQKSNLARV 610
>XP_006716987
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 602 SQKSNLARV 610
>XP_006716986
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 602 SQKSNLARV 610
>XP_006716985
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQRDELARV 9
           SQ+  LARV
Sbjct: 602 SQKSNLARV 610
>XP_005250117
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQRDELAR 8
           S +DELAR
Sbjct: 282 STQDELAR 289
>XP_005265032
          Length = 2545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RDELARV 9
            +DELAR+
Sbjct: 1629 QDELARI 1635
>XP_005265031
          Length = 2569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RDELARV 9
            +DELAR+
Sbjct: 1629 QDELARI 1635
>XP_005265030
          Length = 2595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RDELARV 9
            +DELAR+
Sbjct: 1629 QDELARI 1635
>NP_003583
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQRDELAR 8
           S +DELAR
Sbjct: 282 STQDELAR 289
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.125    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 453,516
Number of extensions: 549
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package