Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           19     665
NP_004561                                                              19     665
NP_001275703                                                           19     665
XP_005253450                                                           19     665
XP_006719151                                                           19     665
NP_060959                                                              18    1935
XP_006711515                                                           18    1935
XP_006711514                                                           18    1935
XP_006711513                                                           18    1935
NP_006805                                                              17    4312
NP_848693                                                              17    4312
XP_006723727                                                           17    4312
XP_005260931                                                           17    4312
XP_005260930                                                           17    4312
NP_079216                                                              16    5631
XP_005273708                                                           16    5631
XP_006716465                                                           16    5631
XP_005273707                                                           16    5631
NP_002901                                                              16    7355
NP_001186704                                                           16    7355
NP_001295                                                              16    7355
NP_477352                                                              16    7355
NP_001124427                                                           16    7355
NP_056133                                                              16    7355
XP_005261692                                                           16    7355
XP_005261691                                                           16    7355
XP_006722772                                                           16    7355
XP_006722771                                                           16    7355
XP_005272522                                                           16    7355
XP_006722770                                                           16    7355
XP_006722769                                                           16    7355
XP_006722768                                                           16    7355
XP_005272521                                                           16    7355
NP_001004488                                                           16    7355
NP_060546                                                              15    9605
NP_001276949                                                           15    9605
NP_001276950                                                           15    9605
NP_001191006                                                           15    9605
NP_004779                                                              15    9605
NP_004216                                                              15    9605
NP_001191031                                                           15    9605
NP_001191030                                                           15    9605
NP_001076442                                                           15    9605
NP_001076441                                                           15    9605
NP_060742                                                              15    9605
NP_068773                                                              15    9605
NP_001274324                                                           15    9605
XP_005266410                                                           15    9605
XP_006719165                                                           15    9605
XP_005253468                                                           15    9605
XP_005253467                                                           15    9605
XP_005253466                                                           15    9605
XP_005253465                                                           15    9605
XP_006719164                                                           15    9605
XP_005253464                                                           15    9605
XP_006719163                                                           15    9605
XP_005253463                                                           15    9605
XP_005252542                                                           15    9605
XP_006717518                                                           15    9605
XP_006717517                                                           15    9605
XP_006717516                                                           15    9605
XP_006712547                                                           15    9605
>NP_001275701
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQMLLNLLE 9
            SQ+LLNLLE
Sbjct: 1151 SQLLLNLLE 1159
>NP_004561
          Length = 1445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQMLLNLLE 9
            SQ+LLNLLE
Sbjct: 1110 SQLLLNLLE 1118
>NP_001275703
          Length = 1264

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           SQ+LLNLLE
Sbjct: 929 SQLLLNLLE 937
>XP_005253450
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQMLLNLLE 9
            SQ+LLNLLE
Sbjct: 1151 SQLLLNLLE 1159
>XP_006719151
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQMLLNLLE 9
            SQ+LLNLLE
Sbjct: 1151 SQLLLNLLE 1159
>NP_060959
          Length = 2964

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    SQMLLNLLE 9
            +Q+LLNLLE
Sbjct: 2920 NQILLNLLE 2928
>XP_006711515
          Length = 2904

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    SQMLLNLLE 9
            +Q+LLNLLE
Sbjct: 2860 NQILLNLLE 2868
>XP_006711514
          Length = 2964

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    SQMLLNLLE 9
            +Q+LLNLLE
Sbjct: 2920 NQILLNLLE 2928
>XP_006711513
          Length = 2964

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    SQMLLNLLE 9
            +Q+LLNLLE
Sbjct: 2920 NQILLNLLE 2928
>NP_006805
          Length = 271

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQMLLNLLE 9
          S M+LN+LE
Sbjct: 87 SSMILNVLE 95
>NP_848693
          Length = 271

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQMLLNLLE 9
          S M+LN+LE
Sbjct: 87 SSMILNVLE 95
>XP_006723727
          Length = 261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQMLLNLLE 9
          S M+LN+LE
Sbjct: 87 SSMILNVLE 95
>XP_005260931
          Length = 263

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQMLLNLLE 9
          S M+LN+LE
Sbjct: 87 SSMILNVLE 95
>XP_005260930
          Length = 263

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQMLLNLLE 9
          S M+LN+LE
Sbjct: 87 SSMILNVLE 95
>NP_079216
          Length = 1870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQMLLNLLE 9
           SQ+L N+LE
Sbjct: 903 SQLLSNILE 911
>XP_005273708
          Length = 1032

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQMLLNLLE 9
           SQ+L N+LE
Sbjct: 617 SQLLSNILE 625
>XP_006716465
          Length = 1826

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQMLLNLLE 9
           SQ+L N+LE
Sbjct: 903 SQLLSNILE 911
>XP_005273707
          Length = 1847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQMLLNLLE 9
           SQ+L N+LE
Sbjct: 903 SQLLSNILE 911
>NP_002901
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   MLLNLLE 9
           MLLNL+E
Sbjct: 194 MLLNLVE 200
>NP_001186704
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++LLNL+E
Sbjct: 325 ELLLNLIE 332
>NP_001295
          Length = 1380

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++LLNL+E
Sbjct: 572 ELLLNLIE 579
>NP_477352
          Length = 2102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++L+NLLE
Sbjct: 728 ELLMNLLE 735
>NP_001124427
          Length = 1173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQMLLNL 7
           SQ+LLNL
Sbjct: 808 SQLLLNL 814
>NP_056133
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQMLLNL 7
           SQ+LLNL
Sbjct: 650 SQLLLNL 656
>XP_005261692
          Length = 1854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++L+NLLE
Sbjct: 756 ELLMNLLE 763
>XP_005261691
          Length = 2099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++L+NLLE
Sbjct: 756 ELLMNLLE 763
>XP_006722772
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQMLLNL 7
           SQ+LLNL
Sbjct: 650 SQLLLNL 656
>XP_006722771
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQMLLNL 7
           SQ+LLNL
Sbjct: 650 SQLLLNL 656
>XP_005272522
          Length = 1088

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQMLLNL 7
           SQ+LLNL
Sbjct: 723 SQLLLNL 729
>XP_006722770
          Length = 1345

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQMLLNL 7
           SQ+LLNL
Sbjct: 980 SQLLLNL 986
>XP_006722769
          Length = 1361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SQMLLNL 7
            SQ+LLNL
Sbjct: 996  SQLLLNL 1002
>XP_006722768
          Length = 1361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SQMLLNL 7
            SQ+LLNL
Sbjct: 996  SQLLLNL 1002
>XP_005272521
          Length = 1426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SQMLLNL 7
            SQ+LLNL
Sbjct: 1061 SQLLLNL 1067
>NP_001004488
          Length = 310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QMLLNLL 8
          QML+NLL
Sbjct: 79 QMLVNLL 85
>NP_060546
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++L+NLLE
Sbjct: 497 EVLINLLE 504
>NP_001276949
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++L+NLLE
Sbjct: 497 EVLINLLE 504
>NP_001276950
          Length = 612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QMLLNLLE 9
          ++L+NLLE
Sbjct: 22 EVLINLLE 29
>NP_001191006
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QMLLNLLE 9
           QML NLL+
Sbjct: 383 QMLKNLLQ 390
>NP_004779
          Length = 1073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QMLLNLLE 9
           QML NLL+
Sbjct: 390 QMLKNLLQ 397
>NP_004216
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QMLLNLLE 9
           Q+LL LLE
Sbjct: 818 QLLLELLE 825
>NP_001191031
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           S+++LNL+E
Sbjct: 95  SKVVLNLIE 103
>NP_001191030
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SQMLLNLLE 9
          S+++LNL+E
Sbjct: 76 SKVVLNLIE 84
>NP_001076442
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           S+++LNL+E
Sbjct: 135 SKVVLNLIE 143
>NP_001076441
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           S+++LNL+E
Sbjct: 199 SKVVLNLIE 207
>NP_060742
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           S+++LNL+E
Sbjct: 141 SKVVLNLIE 149
>NP_068773
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQMLLNLLE 9
           + +LLN+LE
Sbjct: 213 ASLLLNMLE 221
>NP_001274324
          Length = 1688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           Q+LLNL++
Sbjct: 796 QLLLNLVD 803
>XP_005266410
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQMLLNLLE 9
           + +LLN+LE
Sbjct: 213 ASLLLNMLE 221
>XP_006719165
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           S+++LNL+E
Sbjct: 135 SKVVLNLIE 143
>XP_005253468
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           S+++LNL+E
Sbjct: 95  SKVVLNLIE 103
>XP_005253467
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SQMLLNLLE 9
          S+++LNL+E
Sbjct: 23 SKVVLNLIE 31
>XP_005253466
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SQMLLNLLE 9
          S+++LNL+E
Sbjct: 23 SKVVLNLIE 31
>XP_005253465
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SQMLLNLLE 9
          S+++LNL+E
Sbjct: 23 SKVVLNLIE 31
>XP_006719164
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           S+++LNL+E
Sbjct: 199 SKVVLNLIE 207
>XP_005253464
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           S+++LNL+E
Sbjct: 95  SKVVLNLIE 103
>XP_006719163
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           S+++LNL+E
Sbjct: 109 SKVVLNLIE 117
>XP_005253463
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQMLLNLLE 9
           S+++LNL+E
Sbjct: 199 SKVVLNLIE 207
>XP_005252542
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++L+NLLE
Sbjct: 189 EVLINLLE 196
>XP_006717518
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++L+NLLE
Sbjct: 189 EVLINLLE 196
>XP_006717517
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++L+NLLE
Sbjct: 380 EVLINLLE 387
>XP_006717516
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           ++L+NLLE
Sbjct: 465 EVLINLLE 472
>XP_006712547
          Length = 1674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QMLLNLLE 9
           Q+LLNL++
Sbjct: 793 QLLLNLVD 800
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.134    0.313 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 356,063
Number of extensions: 767
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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