Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           19     665
NP_004561                                                              19     665
NP_001275703                                                           19     665
XP_005253450                                                           19     665
XP_006719151                                                           19     665
NP_060959                                                              17    2528
XP_006711515                                                           17    2528
XP_006711514                                                           17    2528
XP_006711513                                                           17    2528
NP_001124427                                                           17    4312
NP_056133                                                              17    4312
XP_006722772                                                           17    4312
XP_006722771                                                           17    4312
XP_005272522                                                           17    4312
XP_006722770                                                           17    4312
XP_006722769                                                           17    4312
XP_006722768                                                           17    4312
XP_005272521                                                           17    4312
NP_001186704                                                           16    5631
NP_001295                                                              16    5631
NP_001274324                                                           16    5631
XP_006712547                                                           16    5631
NP_002215                                                              16    7355
NP_477352                                                              16    7355
NP_056169                                                              16    7355
NP_001243610                                                           16    7355
NP_001243609                                                           16    7355
NP_001243607                                                           16    7355
XP_005261692                                                           16    7355
XP_005261691                                                           16    7355
XP_006720397                                                           16    7355
XP_005268294                                                           16    7355
XP_006715154                                                           16    7355
NP_001243608                                                           16    7355
NP_055487                                                              16    7355
NP_001175                                                              15    9605
NP_079421                                                              15    9605
NP_004216                                                              15    9605
NP_775901                                                              15    9605
XP_005266736                                                           15    9605
XP_006722498                                                           15    9605
XP_006722497                                                           15    9605
XP_005270233                                                           15    9605
XP_005270232                                                           15    9605
XP_005270231                                                           15    9605
XP_005270230                                                           15    9605
XP_005270229                                                           15    9605
XP_005270228                                                           15    9605
NP_001001915                                                           15    9605
>NP_001275701
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQLLLNLME 9
            SQLLLNL+E
Sbjct: 1151 SQLLLNLLE 1159
>NP_004561
          Length = 1445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQLLLNLME 9
            SQLLLNL+E
Sbjct: 1110 SQLLLNLLE 1118
>NP_001275703
          Length = 1264

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SQLLLNLME 9
           SQLLLNL+E
Sbjct: 929 SQLLLNLLE 937
>XP_005253450
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQLLLNLME 9
            SQLLLNL+E
Sbjct: 1151 SQLLLNLLE 1159
>XP_006719151
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SQLLLNLME 9
            SQLLLNL+E
Sbjct: 1151 SQLLLNLLE 1159
>NP_060959
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    SQLLLNLME 9
            +Q+LLNL+E
Sbjct: 2920 NQILLNLLE 2928
>XP_006711515
          Length = 2904

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    SQLLLNLME 9
            +Q+LLNL+E
Sbjct: 2860 NQILLNLLE 2868
>XP_006711514
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    SQLLLNLME 9
            +Q+LLNL+E
Sbjct: 2920 NQILLNLLE 2928
>XP_006711513
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    SQLLLNLME 9
            +Q+LLNL+E
Sbjct: 2920 NQILLNLLE 2928
>NP_001124427
          Length = 1173

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SQLLLNL 7
           SQLLLNL
Sbjct: 808 SQLLLNL 814
>NP_056133
          Length = 1015

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SQLLLNL 7
           SQLLLNL
Sbjct: 650 SQLLLNL 656
>XP_006722772
          Length = 1015

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SQLLLNL 7
           SQLLLNL
Sbjct: 650 SQLLLNL 656
>XP_006722771
          Length = 1015

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SQLLLNL 7
           SQLLLNL
Sbjct: 650 SQLLLNL 656
>XP_005272522
          Length = 1088

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SQLLLNL 7
           SQLLLNL
Sbjct: 723 SQLLLNL 729
>XP_006722770
          Length = 1345

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SQLLLNL 7
           SQLLLNL
Sbjct: 980 SQLLLNL 986
>XP_006722769
          Length = 1361

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    SQLLLNL 7
            SQLLLNL
Sbjct: 996  SQLLLNL 1002
>XP_006722768
          Length = 1361

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    SQLLLNL 7
            SQLLLNL
Sbjct: 996  SQLLLNL 1002
>XP_005272521
          Length = 1426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    SQLLLNL 7
            SQLLLNL
Sbjct: 1061 SQLLLNL 1067
>NP_001186704
          Length = 1133

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QLLLNLME 9
           +LLLNL+E
Sbjct: 325 ELLLNLIE 332
>NP_001295
          Length = 1380

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QLLLNLME 9
           +LLLNL+E
Sbjct: 572 ELLLNLIE 579
>NP_001274324
          Length = 1688

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QLLLNLME 9
           QLLLNL++
Sbjct: 796 QLLLNLVD 803
>XP_006712547
          Length = 1674

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QLLLNLME 9
           QLLLNL++
Sbjct: 793 QLLLNLVD 800
>NP_002215
          Length = 2671

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SQLLLNLME 9
            S+LLL LME
Sbjct: 1997 SKLLLALME 2005
>NP_477352
          Length = 2102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLLLNLME 9
           +LL+NL+E
Sbjct: 728 ELLMNLLE 735
>NP_056169
          Length = 1749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SQLLLNLME 9
            SQL+LN+ E
Sbjct: 1228 SQLVLNVCE 1236
>NP_001243610
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SQLLLNLM 8
          SQLLLN++
Sbjct: 51 SQLLLNVV 58
>NP_001243609
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SQLLLNLM 8
          SQLLLN++
Sbjct: 51 SQLLLNVV 58
>NP_001243607
          Length = 567

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SQLLLNLM 8
           SQLLLN++
Sbjct: 407 SQLLLNVV 414
>XP_005261692
          Length = 1854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLLLNLME 9
           +LL+NL+E
Sbjct: 756 ELLMNLLE 763
>XP_005261691
          Length = 2099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLLLNLME 9
           +LL+NL+E
Sbjct: 756 ELLMNLLE 763
>XP_006720397
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SQLLLNLM 8
           SQLLLN++
Sbjct: 423 SQLLLNVV 430
>XP_005268294
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SQLLLNLM 8
           SQLLLN++
Sbjct: 423 SQLLLNVV 430
>XP_006715154
          Length = 2700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SQLLLNLME 9
            S+LLL LME
Sbjct: 2026 SKLLLALME 2034
>NP_001243608
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SQLLLNLM 8
           SQLLLN++
Sbjct: 328 SQLLLNVV 335
>NP_055487
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SQLLLNLM 8
           SQLLLN++
Sbjct: 423 SQLLLNVV 430
>NP_001175
          Length = 2644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLNLME 9
           LLNLME
Sbjct: 809 LLNLME 814
>NP_079421
          Length = 1665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQLLLNLME 9
           S+ +LN+ME
Sbjct: 818 SKTILNMME 826
>NP_004216
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLLLNLME 9
           QLLL L+E
Sbjct: 818 QLLLELLE 825
>NP_775901
          Length = 2226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    LLLNLME 9
            LLLN ME
Sbjct: 1218 LLLNFME 1224
>XP_005266736
          Length = 1314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLLNLME 9
           LLLN ME
Sbjct: 306 LLLNFME 312
>XP_006722498
          Length = 2059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    LLLNLME 9
            LLLN ME
Sbjct: 1219 LLLNFME 1225
>XP_006722497
          Length = 2227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    LLLNLME 9
            LLLN ME
Sbjct: 1219 LLLNFME 1225
>XP_005270233
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SQLLLNLME 9
          S+ +LN+ME
Sbjct: 80 SKTILNMME 88
>XP_005270232
          Length = 1535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQLLLNLME 9
           S+ +LN+ME
Sbjct: 819 SKTILNMME 827
>XP_005270231
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQLLLNLME 9
           S+ +LN+ME
Sbjct: 819 SKTILNMME 827
>XP_005270230
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQLLLNLME 9
           S+ +LN+ME
Sbjct: 780 SKTILNMME 788
>XP_005270229
          Length = 1637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQLLLNLME 9
           S+ +LN+ME
Sbjct: 819 SKTILNMME 827
>XP_005270228
          Length = 1666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQLLLNLME 9
           S+ +LN+ME
Sbjct: 819 SKTILNMME 827
>NP_001001915
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QLLLNLME 9
          QLL+NL E
Sbjct: 83 QLLVNLWE 90
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.134    0.313 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 366,178
Number of extensions: 663
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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