Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000305                                                              20     390
XP_006717990                                                           20     390
XP_006717989                                                           20     390
NP_859526                                                              18    1935
NP_002543                                                              18    1935
NP_001177810                                                           18    1935
NP_001177808                                                           18    1935
NP_001177811                                                           18    1935
NP_859525                                                              18    1935
NP_057125                                                              18    1935
XP_006721602                                                           18    1935
XP_006712619                                                           18    1935
NP_001129223                                                           17    2528
NP_001002862                                                           17    2528
NP_940842                                                              17    2528
XP_006725473                                                           17    2528
XP_005261881                                                           17    2528
NP_056270                                                              17    3301
NP_001026916                                                           17    3301
XP_006714963                                                           17    3301
XP_006714962                                                           17    3301
XP_005266010                                                           17    3301
NP_219485                                                              16    5631
NP_001011699                                                           16    5631
XP_005260211                                                           16    5631
NP_037528                                                              16    7355
NP_001269970                                                           16    7355
NP_001243638                                                           16    7355
NP_001269971                                                           16    7355
NP_001243636                                                           16    7355
NP_055700                                                              16    7355
NP_001122089                                                           16    7355
NP_114128                                                              16    7355
NP_001273541                                                           16    7355
NP_001273540                                                           16    7355
NP_001121186                                                           16    7355
NP_001243637                                                           16    7355
NP_078779                                                              16    7355
NP_055754                                                              16    7355
NP_055699                                                              16    7355
NP_001017392                                                           16    7355
NP_001243635                                                           16    7355
XP_005261006                                                           16    7355
XP_006724055                                                           16    7355
XP_006722483                                                           16    7355
XP_005258291                                                           16    7355
XP_005258290                                                           16    7355
XP_005256729                                                           16    7355
XP_005267236                                                           16    7355
XP_006715650                                                           16    7355
XP_005267234                                                           16    7355
XP_006714123                                                           16    7355
XP_006714122                                                           16    7355
XP_006714121                                                           16    7355
XP_006710872                                                           16    7355
XP_006710871                                                           16    7355
NP_000616                                                              15    9605
NP_848519                                                              15    9605
NP_036251                                                              15    9605
NP_848563                                                              15    9605
NP_001034892                                                           15    9605
NP_009098                                                              15    9605
NP_203754                                                              15    9605
XP_003960163                                                           15    9605
XP_006725474                                                           15    9605
XP_006725020                                                           15    9605
XP_006724434                                                           15    9605
XP_006718788                                                           15    9605
XP_005274419                                                           15    9605
XP_005251917                                                           15    9605
XP_006711147                                                           15    9605
NP_001139653                                                           15    9605
>NP_000305
          Length = 403

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QLELIKPF 9
           QLELIKPF
Sbjct: 97  QLELIKPF 104
>XP_006717990
          Length = 175

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  QLELIKPF 9
          QLELIKPF
Sbjct: 82 QLELIKPF 89
>XP_006717989
          Length = 388

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  QLELIKPF 9
          QLELIKPF
Sbjct: 82 QLELIKPF 89
>NP_859526
          Length = 436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLELIKP
Sbjct: 381 QLELIKP 387
>NP_002543
          Length = 436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLELIKP
Sbjct: 381 QLELIKP 387
>NP_001177810
          Length = 352

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLELIKP
Sbjct: 297 QLELIKP 303
>NP_001177808
          Length = 436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLELIKP
Sbjct: 381 QLELIKP 387
>NP_001177811
          Length = 362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLELIKP
Sbjct: 307 QLELIKP 313
>NP_859525
          Length = 436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLELIKP
Sbjct: 381 QLELIKP 387
>NP_057125
          Length = 239

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  QLELIKPF 9
          QLELI PF
Sbjct: 32 QLELITPF 39
>XP_006721602
          Length = 244

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  QLELIKPF 9
          QLELI PF
Sbjct: 37 QLELITPF 44
>XP_006712619
          Length = 352

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLELIKP
Sbjct: 297 QLELIKP 303
>NP_001129223
          Length = 239

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QLELIKPF 9
          QLEL+ PF
Sbjct: 32 QLELLSPF 39
>NP_001002862
          Length = 235

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QLELIKPF 9
          QLEL+ PF
Sbjct: 32 QLELLSPF 39
>NP_940842
          Length = 205

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QLELIKPF 9
          QLEL+ PF
Sbjct: 32 QLELLSPF 39
>XP_006725473
          Length = 239

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QLELIKPF 9
          QLEL+ PF
Sbjct: 32 QLELLSPF 39
>XP_005261881
          Length = 239

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QLELIKPF 9
          QLEL+ PF
Sbjct: 32 QLELLSPF 39
>NP_056270
          Length = 557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQLELIKPF 9
           +QLEL+ PF
Sbjct: 536 AQLELLLPF 544
>NP_001026916
          Length = 320

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SQLELIKP 8
           ++LELIKP
Sbjct: 290 AELELIKP 297
>XP_006714963
          Length = 552

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQLELIKPF 9
           +QLEL+ PF
Sbjct: 531 AQLELLLPF 539
>XP_006714962
          Length = 557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQLELIKPF 9
           +QLEL+ PF
Sbjct: 536 AQLELLLPF 544
>XP_005266010
          Length = 557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SQLELIKPF 9
           +QLEL+ PF
Sbjct: 536 AQLELLLPF 544
>NP_219485
          Length = 410

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SQLELIKPF 9
           +Q+E++ PF
Sbjct: 214 AQIEMLSPF 222
>NP_001011699
          Length = 409

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SQLELIKPF 9
           +Q+E++ PF
Sbjct: 213 AQIEMLSPF 221
>XP_005260211
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  SQLELIKPF 9
          +Q+E++ PF
Sbjct: 69 AQIEMLSPF 77
>NP_037528
          Length = 1055

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SQLELIKP 8
           ++LE+IKP
Sbjct: 849 AKLEMIKP 856
>NP_001269970
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SQLELIKP 8
           ++LE+IKP
Sbjct: 919 AKLEMIKP 926
>NP_001243638
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLEL++P
Sbjct: 121 QLELVEP 127
>NP_001269971
          Length = 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SQLELIKP 8
           ++LE+IKP
Sbjct: 881 AKLEMIKP 888
>NP_001243636
          Length = 185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLEL++P
Sbjct: 110 QLELVEP 116
>NP_055700
          Length = 185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLEL++P
Sbjct: 110 QLELVEP 116
>NP_001122089
          Length = 769

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLELIKPF 9
           QLE ++PF
Sbjct: 759 QLEQLRPF 766
>NP_114128
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLELIKPF 9
           QLE ++PF
Sbjct: 785 QLEQLRPF 792
>NP_001273541
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLELIKPF 9
           QLE ++PF
Sbjct: 695 QLEQLRPF 702
>NP_001273540
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLELIKPF 9
           QLE ++PF
Sbjct: 786 QLEQLRPF 793
>NP_001121186
          Length = 2405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QLELIKP 8
            +LEL+KP
Sbjct: 1461 KLELVKP 1467
>NP_001243637
          Length = 185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLEL++P
Sbjct: 110 QLELVEP 116
>NP_078779
          Length = 2406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QLELIKP 8
            +LEL+KP
Sbjct: 1461 KLELVKP 1467
>NP_055754
          Length = 1435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ELIKPF 9
          EL+KPF
Sbjct: 41 ELLKPF 46
>NP_055699
          Length = 1082

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ELIKPF 9
           E+IKPF
Sbjct: 420 EIIKPF 425
>NP_001017392
          Length = 1082

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ELIKPF 9
           E+IKPF
Sbjct: 420 EIIKPF 425
>NP_001243635
          Length = 185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLEL++P
Sbjct: 110 QLELVEP 116
>XP_005261006
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SQLELIKP 8
           ++LE+IKP
Sbjct: 515 AKLEMIKP 522
>XP_006724055
          Length = 826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SQLELIKP 8
           ++LE+IKP
Sbjct: 620 AKLEMIKP 627
>XP_006722483
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ELIKPF 9
          EL+KPF
Sbjct: 41 ELLKPF 46
>XP_005258291
          Length = 1406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ELIKPF 9
          EL+KPF
Sbjct: 41 ELLKPF 46
>XP_005258290
          Length = 1436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ELIKPF 9
          EL+KPF
Sbjct: 41 ELLKPF 46
>XP_005256729
          Length = 238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LELIKPF 9
          LELI PF
Sbjct: 32 LELITPF 38
>XP_005267236
          Length = 768

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLELIKPF 9
           QLE ++PF
Sbjct: 758 QLEQLRPF 765
>XP_006715650
          Length = 775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLELIKPF 9
           QLE ++PF
Sbjct: 765 QLEQLRPF 772
>XP_005267234
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLELIKPF 9
           QLE ++PF
Sbjct: 785 QLEQLRPF 792
>XP_006714123
          Length = 185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLEL++P
Sbjct: 110 QLELVEP 116
>XP_006714122
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLEL++P
Sbjct: 121 QLELVEP 127
>XP_006714121
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QLELIKP 8
           QLEL++P
Sbjct: 140 QLELVEP 146
>XP_006710872
          Length = 1590

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QLELIKP 8
            +LEL+KP
Sbjct: 1461 KLELVKP 1467
>XP_006710871
          Length = 2406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QLELIKP 8
            +LEL+KP
Sbjct: 1461 KLELVKP 1467
>NP_000616
          Length = 1153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SQLELIKP 8
           SQL ++KP
Sbjct: 898 SQLPILKP 905
>NP_848519
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ELIKPF 9
           ELI+PF
Sbjct: 329 ELIRPF 334
>NP_036251
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ELIKPF 9
           ELI+PF
Sbjct: 316 ELIRPF 321
>NP_848563
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLELIKPF 9
           QL+L+ PF
Sbjct: 507 QLDLLVPF 514
>NP_001034892
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ELIKPF 9
           ELI+PF
Sbjct: 337 ELIRPF 342
>NP_009098
          Length = 1325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ELIKPF 9
           ELIKP+
Sbjct: 851 ELIKPY 856
>NP_203754
          Length = 1729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQLELIKPF 9
           SQL L +PF
Sbjct: 456 SQLALDRPF 464
>XP_003960163
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQLELIK 7
           +QLELIK
Sbjct: 265 NQLELIK 271
>XP_006725474
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  LELIKPF 9
          LEL+ PF
Sbjct: 32 LELLSPF 38
>XP_006725020
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQLELIK 7
           +QLELIK
Sbjct: 265 NQLELIK 271
>XP_006724434
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  LELIKPF 9
          LEL+ PF
Sbjct: 32 LELLSPF 38
>XP_006718788
          Length = 1729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQLELIKPF 9
           SQL L +PF
Sbjct: 456 SQLALDRPF 464
>XP_005274419
          Length = 1808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SQLELIKPF 9
           SQL L +PF
Sbjct: 535 SQLALDRPF 543
>XP_005251917
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ELIKPF 9
           ELI+PF
Sbjct: 342 ELIRPF 347
>XP_006711147
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQLELIK 7
           +QLELIK
Sbjct: 265 NQLELIK 271
>NP_001139653
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQLELIK 7
           +QLELIK
Sbjct: 265 NQLELIK 271
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.143    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 574,957
Number of extensions: 1078
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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