Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     869
NP_001185763                                                           19     869
NP_055459                                                              19     869
NP_001002811                                                           19     869
NP_001002812                                                           19     869
XP_006726410                                                           19     869
XP_006711719                                                           19     869
XP_006711717                                                           19     869
XP_006711716                                                           19     869
XP_006711715                                                           19     869
XP_006711714                                                           19     869
XP_006711713                                                           19     869
XP_006711712                                                           19     869
XP_006711711                                                           19     869
XP_006711710                                                           19     869
XP_006711709                                                           19     869
XP_005277503                                                           19     869
XP_005273038                                                           19     869
XP_006711708                                                           19     869
XP_005277500                                                           19     869
XP_006711707                                                           19     869
XP_005277499                                                           19     869
XP_006711706                                                           19     869
XP_006711705                                                           19     869
XP_006711164                                                           19     869
XP_006710144                                                           19     869
NP_110447                                                              17    4312
NP_001269316                                                           17    4312
NP_005887                                                              17    4312
NP_001269315                                                           17    4312
NP_079194                                                              17    4312
NP_001138790                                                           17    4312
NP_001138788                                                           17    4312
NP_001138789                                                           17    4312
NP_001138787                                                           17    4312
XP_006723939                                                           17    4312
XP_005260616                                                           17    4312
XP_005260615                                                           17    4312
XP_006715287                                                           17    4312
XP_006715286                                                           17    4312
XP_003846647                                                           17    4312
NP_003310                                                              16    5631
NP_597676                                                              16    5631
NP_596870                                                              16    5631
NP_001243779                                                           16    5631
NP_596869                                                              16    5631
NP_060754                                                              16    5631
XP_006712787                                                           16    5631
XP_006712786                                                           16    5631
XP_005270801                                                           16    5631
XP_005270800                                                           16    5631
XP_005270799                                                           16    5631
XP_006710637                                                           16    5631
NP_001254479                                                           16    5631
NP_597681                                                              16    5631
NP_001804                                                              16    7355
NP_001273663                                                           16    7355
NP_001263408                                                           16    7355
NP_001263409                                                           16    7355
NP_004784                                                              16    7355
NP_115948                                                              16    7355
NP_001254514                                                           15    9605
NP_001254515                                                           15    9605
NP_001186074                                                           15    9605
NP_001186072                                                           15    9605
NP_001073278                                                           15    9605
NP_001001850                                                           15    9605
XP_006721484                                                           15    9605
XP_006721483                                                           15    9605
XP_005247513                                                           15    9605
XP_005247512                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 417 SQLEIQKLQ 425
>NP_001185763
          Length = 2362

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 351 SQLEIQKLQ 359
>NP_055459
          Length = 2346

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 351 SQLEIQKLQ 359
>NP_001002811
          Length = 1132

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>NP_001002812
          Length = 969

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 351 SQLEIQKLQ 359
>XP_006726410
          Length = 2087

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 426 SQLEIQKLQ 434
>XP_006711719
          Length = 2302

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 417 SQLEIQKLQ 425
>XP_006711717
          Length = 2385

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 417 SQLEIQKLQ 425
>XP_006711716
          Length = 2411

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 417 SQLEIQKLQ 425
>XP_006711715
          Length = 2428

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 351 SQLEIQKLQ 359
>XP_006711714
          Length = 2429

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 351 SQLEIQKLQ 359
>XP_006711713
          Length = 2432

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 354 SQLEIQKLQ 362
>XP_006711712
          Length = 2473

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>XP_006711711
          Length = 2482

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>XP_006711710
          Length = 2494

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 417 SQLEIQKLQ 425
>XP_006711709
          Length = 2495

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 417 SQLEIQKLQ 425
>XP_005277503
          Length = 2498

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>XP_005273038
          Length = 2509

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>XP_006711708
          Length = 2512

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>XP_005277500
          Length = 2525

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>XP_006711707
          Length = 2553

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>XP_005277499
          Length = 2561

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>XP_006711706
          Length = 2591

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>XP_006711705
          Length = 2592

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>XP_006711164
          Length = 2087

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 426 SQLEIQKLQ 434
>XP_006710144
          Length = 564

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SQFEIQKLQ 9
           SQ EIQKLQ
Sbjct: 514 SQLEIQKLQ 522
>NP_110447
          Length = 957

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QFEIQKLQ 9
           QF++QKL+
Sbjct: 400 QFDVQKLR 407
>NP_001269316
          Length = 414

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQFEIQKL 8
           SQFE QK+
Sbjct: 237 SQFEAQKI 244
>NP_005887
          Length = 414

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQFEIQKL 8
           SQFE QK+
Sbjct: 237 SQFEAQKI 244
>NP_001269315
          Length = 414

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQFEIQKL 8
           SQFE QK+
Sbjct: 237 SQFEAQKI 244
>NP_079194
          Length = 356

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           QF IQKL+
Sbjct: 143 QFSIQKLE 150
>NP_001138790
          Length = 340

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           QF IQKL+
Sbjct: 127 QFSIQKLE 134
>NP_001138788
          Length = 356

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           QF IQKL+
Sbjct: 143 QFSIQKLE 150
>NP_001138789
          Length = 249

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QFEIQKLQ 9
          QF IQKL+
Sbjct: 36 QFSIQKLE 43
>NP_001138787
          Length = 356

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           QF IQKL+
Sbjct: 143 QFSIQKLE 150
>XP_006723939
          Length = 249

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QFEIQKLQ 9
          QF IQKL+
Sbjct: 36 QFSIQKLE 43
>XP_005260616
          Length = 334

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           QF IQKL+
Sbjct: 121 QFSIQKLE 128
>XP_005260615
          Length = 441

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           QF IQKL+
Sbjct: 228 QFSIQKLE 235
>XP_006715287
          Length = 615

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QFEIQKLQ 9
           QF++QKL+
Sbjct: 400 QFDVQKLR 407
>XP_006715286
          Length = 945

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QFEIQKLQ 9
           QF++QKL+
Sbjct: 400 QFDVQKLR 407
>XP_003846647
          Length = 516

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SQFEIQK 7
          SQFEI+K
Sbjct: 18 SQFEIEK 24
>NP_003310
          Length = 26926

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QFEIQKL 8
            QFE+QK+
Sbjct: 1912 QFEVQKV 1918
>NP_597676
          Length = 27051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QFEIQKL 8
            QFE+QK+
Sbjct: 1912 QFEVQKV 1918
>NP_596870
          Length = 5604

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QFEIQKL 8
            QFE+QK+
Sbjct: 1958 QFEVQKV 1964
>NP_001243779
          Length = 34350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QFEIQKL 8
            QFE+QK+
Sbjct: 1958 QFEVQKV 1964
>NP_596869
          Length = 33423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QFEIQKL 8
            QFE+QK+
Sbjct: 1958 QFEVQKV 1964
>NP_060754
          Length = 595

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           Q EIQKLQ
Sbjct: 571 QNEIQKLQ 578
>XP_006712787
          Length = 33978

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QFEIQKL 8
            QFE+QK+
Sbjct: 1959 QFEVQKV 1965
>XP_006712786
          Length = 35484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QFEIQKL 8
            QFE+QK+
Sbjct: 1959 QFEVQKV 1965
>XP_005270801
          Length = 461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           Q EIQKLQ
Sbjct: 437 QNEIQKLQ 444
>XP_005270800
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           Q EIQKLQ
Sbjct: 492 QNEIQKLQ 499
>XP_005270799
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           Q EIQKLQ
Sbjct: 492 QNEIQKLQ 499
>XP_006710637
          Length = 568

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           Q EIQKLQ
Sbjct: 544 QNEIQKLQ 551
>NP_001254479
          Length = 35991

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QFEIQKL 8
            QFE+QK+
Sbjct: 1958 QFEVQKV 1964
>NP_597681
          Length = 27118

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QFEIQKL 8
            QFE+QK+
Sbjct: 1912 QFEVQKV 1918
>NP_001804
          Length = 2701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QFEIQKL 8
            QFE QKL
Sbjct: 1652 QFETQKL 1658
>NP_001273663
          Length = 2580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QFEIQKL 8
            QFE QKL
Sbjct: 1627 QFETQKL 1633
>NP_001263408
          Length = 895

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           +FE+ KLQ
Sbjct: 305 EFELSKLQ 312
>NP_001263409
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           +FE+ KLQ
Sbjct: 173 EFELSKLQ 180
>NP_004784
          Length = 959

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QFEIQKLQ 9
           +FE+ KLQ
Sbjct: 369 EFELSKLQ 376
>NP_115948
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FEIQKLQ 9
           +EIQKLQ
Sbjct: 151 WEIQKLQ 157
>NP_001254514
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EIQKLQ 9
           EIQKLQ
Sbjct: 887 EIQKLQ 892
>NP_001254515
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EIQKLQ 9
           EIQKLQ
Sbjct: 834 EIQKLQ 839
>NP_001186074
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SQFEIQKLQ 9
           +++EI+KL+
Sbjct: 523 NEYEIEKLE 531
>NP_001186072
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SQFEIQKLQ 9
           +++EI+KL+
Sbjct: 778 NEYEIEKLE 786
>NP_001073278
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SQFEIQKLQ 9
           +++EI+KL+
Sbjct: 745 NEYEIEKLE 753
>NP_001001850
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  EIQKLQ 9
          EIQKLQ
Sbjct: 53 EIQKLQ 58
>XP_006721484
          Length = 997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EIQKLQ 9
           EIQKLQ
Sbjct: 832 EIQKLQ 837
>XP_006721483
          Length = 1061

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EIQKLQ 9
           EIQKLQ
Sbjct: 896 EIQKLQ 901
>XP_005247513
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  EIQKLQ 9
          EIQKLQ
Sbjct: 53 EIQKLQ 58
>XP_005247512
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  EIQKLQ 9
          EIQKLQ
Sbjct: 53 EIQKLQ 58
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.128    0.307 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 444,877
Number of extensions: 1114
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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