Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           21     229
NP_004561                                                              21     229
NP_001275703                                                           21     229
XP_005253450                                                           21     229
XP_006719151                                                           21     229
NP_036542                                                              18    1482
NP_001107572                                                           18    1482
NP_001107571                                                           18    1482
NP_963869                                                              18    1482
NP_001230262                                                           18    1482
NP_001230261                                                           18    1482
XP_005255309                                                           18    1482
NP_919260                                                              18    1482
NP_001104292                                                           17    2528
NP_808592                                                              17    4312
NP_004306                                                              17    4312
NP_001120977                                                           17    4312
XP_005273561                                                           17    4312
NP_006562                                                              16    5631
NP_689948                                                              16    5631
NP_005531                                                              16    7355
NP_055534                                                              16    7355
NP_056264                                                              16    7355
NP_001092086                                                           16    7355
NP_001193867                                                           16    7355
NP_001193870                                                           16    7355
XP_006716256                                                           16    7355
XP_006716255                                                           16    7355
XP_006716254                                                           16    7355
XP_006716253                                                           16    7355
XP_005250134                                                           16    7355
XP_005250133                                                           16    7355
XP_005250132                                                           16    7355
XP_005250131                                                           16    7355
XP_005245134                                                           16    7355
XP_005270894                                                           16    7355
XP_005270892                                                           16    7355
NP_620077                                                              16    7355
NP_001269557                                                           15    9605
NP_001269560                                                           15    9605
NP_000038                                                              15    9605
NP_004130                                                              15    9605
NP_065128                                                              15    9605
NP_001135943                                                           15    9605
NP_620686                                                              15    9605
NP_071445                                                              15    9605
NP_055025                                                              15    9605
NP_001003927                                                           15    9605
NP_001010980                                                           15    9605
XP_005274578                                                           15    9605
XP_005274576                                                           15    9605
XP_005274575                                                           15    9605
XP_006721306                                                           15    9605
XP_006721305                                                           15    9605
XP_005256141                                                           15    9605
XP_005271476                                                           15    9605
XP_006718836                                                           15    9605
XP_005263206                                                           15    9605
XP_005263205                                                           15    9605
XP_005245929                                                           15    9605
NP_001001824                                                           15    9605
NP_001935                                                              15    9605
>NP_001275701
          Length = 1486

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SPVTVQIDF 9
           SPVT+QIDF
Sbjct: 660 SPVTLQIDF 668
>NP_004561
          Length = 1445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SPVTVQIDF 9
           SPVT+QIDF
Sbjct: 619 SPVTLQIDF 627
>NP_001275703
          Length = 1264

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SPVTVQIDF 9
           SPVT+QIDF
Sbjct: 438 SPVTLQIDF 446
>XP_005253450
          Length = 1486

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SPVTVQIDF 9
           SPVT+QIDF
Sbjct: 660 SPVTLQIDF 668
>XP_006719151
          Length = 1486

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SPVTVQIDF 9
           SPVT+QIDF
Sbjct: 660 SPVTLQIDF 668
>NP_036542
          Length = 853

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPVTVQIDF 9
           SP+TV+ DF
Sbjct: 828 SPITVESDF 836
>NP_001107572
          Length = 809

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPVTVQIDF 9
           SP+TV+ DF
Sbjct: 784 SPITVESDF 792
>NP_001107571
          Length = 840

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPVTVQIDF 9
           SP+TV+ DF
Sbjct: 815 SPITVESDF 823
>NP_963869
          Length = 910

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPVTVQIDF 9
           SP+TV+ DF
Sbjct: 885 SPITVESDF 893
>NP_001230262
          Length = 879

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPVTVQIDF 9
           SP+TV+ DF
Sbjct: 854 SPITVESDF 862
>NP_001230261
          Length = 923

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPVTVQIDF 9
           SP+TV+ DF
Sbjct: 898 SPITVESDF 906
>XP_005255309
          Length = 859

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPVTVQIDF 9
           SP+TV+ DF
Sbjct: 834 SPITVESDF 842
>NP_919260
          Length = 292

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPVTVQIDF 9
           SPVTVQ+ +
Sbjct: 150 SPVTVQVSY 158
>NP_001104292
          Length = 395

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PVTVQIDF 9
           PVT+ IDF
Sbjct: 132 PVTLHIDF 139
>NP_808592
          Length = 395

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVTVQIDF 9
           P+TV +DF
Sbjct: 184 PLTVNLDF 191
>NP_004306
          Length = 411

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVTVQIDF 9
           P+TV +DF
Sbjct: 200 PLTVNLDF 207
>NP_001120977
          Length = 389

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVTVQIDF 9
           P+TV +DF
Sbjct: 178 PLTVNLDF 185
>XP_005273561
          Length = 373

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVTVQIDF 9
           P+TV +DF
Sbjct: 162 PLTVNLDF 169
>NP_006562
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVTVQIDF 9
           P T+Q+DF
Sbjct: 159 PQTLQLDF 166
>NP_689948
          Length = 473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SPVTVQIDF 9
          +P T+QI+F
Sbjct: 19 APRTIQIEF 27
>NP_005531
          Length = 913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           S VTVQ+D
Sbjct: 95  SDVTVQLD 102
>NP_055534
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 527 SPITVEVN 534
>NP_056264
          Length = 219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SPVTVQIDF 9
           SP T+Q+ +
Sbjct: 181 SPTTIQVTY 189
>NP_001092086
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SPVTVQIDF 9
           SP T+Q+ +
Sbjct: 215 SPTTIQVTY 223
>NP_001193867
          Length = 919

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 527 SPITVEVN 534
>NP_001193870
          Length = 497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 103 SPITVEVN 110
>XP_006716256
          Length = 919

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 527 SPITVEVN 534
>XP_006716255
          Length = 919

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 527 SPITVEVN 534
>XP_006716254
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 527 SPITVEVN 534
>XP_006716253
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 527 SPITVEVN 534
>XP_005250134
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 527 SPITVEVN 534
>XP_005250133
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 527 SPITVEVN 534
>XP_005250132
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 527 SPITVEVN 534
>XP_005250131
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SPVTVQID 8
           SP+TV+++
Sbjct: 527 SPITVEVN 534
>XP_005245134
          Length = 235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SPVTVQIDF 9
           SP T+Q+ +
Sbjct: 197 SPTTIQVTY 205
>XP_005270894
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           S VTVQ+D
Sbjct: 95  SDVTVQLD 102
>XP_005270892
          Length = 801

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           S VTVQ+D
Sbjct: 95  SDVTVQLD 102
>NP_620077
          Length = 201

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SPVTVQIDF 9
           SP T+Q+ +
Sbjct: 163 SPTTIQVTY 171
>NP_001269557
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           SPV +Q+D
Sbjct: 578 SPVPLQLD 585
>NP_001269560
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           SPV +Q+D
Sbjct: 508 SPVPLQLD 515
>NP_000038
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           SPV +Q+D
Sbjct: 553 SPVPLQLD 560
>NP_004130
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   PVTVQID 8
           PVT +ID
Sbjct: 217 PVTTEID 223
>NP_065128
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   SPVTVQ 6
           SP+TVQ
Sbjct: 128 SPITVQ 133
>NP_001135943
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   SPVTVQ 6
           SP+TVQ
Sbjct: 128 SPITVQ 133
>NP_620686
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SPVTVQID 8
           SP  +QID
Sbjct: 391 SPTLIQID 398
>NP_071445
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   PVTVQIDF 9
           PV +Q+D+
Sbjct: 792 PVALQLDY 799
>NP_055025
          Length = 236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1  SPVTVQIDF 9
          +P+T ++D+
Sbjct: 62 NPITPEVDY 70
>NP_001003927
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1  SPVTVQIDF 9
          +P+T ++D+
Sbjct: 85 NPITPEVDY 93
>NP_001010980
          Length = 102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           SPV VQ++
Sbjct: 93  SPVDVQVE 100
>XP_005274578
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           SPV +Q+D
Sbjct: 499 SPVPLQLD 506
>XP_005274576
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           SPV +Q+D
Sbjct: 553 SPVPLQLD 560
>XP_005274575
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           SPV +Q+D
Sbjct: 562 SPVPLQLD 569
>XP_006721306
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   PVTVQIDF 9
           PV +Q+D+
Sbjct: 765 PVALQLDY 772
>XP_006721305
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   PVTVQIDF 9
           PV +Q+D+
Sbjct: 765 PVALQLDY 772
>XP_005256141
          Length = 1013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   PVTVQIDF 9
           PV +Q+D+
Sbjct: 765 PVALQLDY 772
>XP_005271476
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SPVTVQID 8
          SP  +QID
Sbjct: 60 SPTLIQID 67
>XP_006718836
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SPVTVQID 8
          SP  +QID
Sbjct: 83 SPTLIQID 90
>XP_005263206
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   SPVTVQ 6
           SP+TVQ
Sbjct: 128 SPITVQ 133
>XP_005263205
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   SPVTVQ 6
           SP+TVQ
Sbjct: 128 SPITVQ 133
>XP_005245929
          Length = 102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPVTVQID 8
           SPV VQ++
Sbjct: 93  SPVDVQVE 100
>NP_001001824
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SPVTVQIDF 9
           +PVT+Q  F
Sbjct: 160 TPVTMQFPF 168
>NP_001935
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SPVTVQI 7
           +PVT+Q+
Sbjct: 368 TPVTIQV 374
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.139    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 544,126
Number of extensions: 1084
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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