Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001006608                                                           18    1935
NP_955372                                                              18    1935
NP_055649                                                              18    1935
XP_005275724                                                           18    1935
XP_005275722                                                           18    1935
XP_005275721                                                           18    1935
XP_006725345                                                           18    1935
XP_006725344                                                           18    1935
XP_005275719                                                           18    1935
XP_006725343                                                           18    1935
XP_006725342                                                           18    1935
XP_005275717                                                           18    1935
XP_005275716                                                           18    1935
XP_005257941                                                           18    1935
XP_005257940                                                           18    1935
XP_006722274                                                           18    1935
XP_006722273                                                           18    1935
XP_005257939                                                           18    1935
XP_006722272                                                           18    1935
XP_005257937                                                           18    1935
XP_005257936                                                           18    1935
XP_005257935                                                           18    1935
XP_006722271                                                           18    1935
NP_004110                                                              17    2528
NP_003740                                                              17    4312
XP_006711469                                                           17    4312
XP_005245352                                                           17    4312
NP_001276953                                                           16    7355
NP_714912                                                              16    7355
NP_001276952                                                           16    7355
NP_005526                                                              16    7355
NP_001171655                                                           16    7355
NP_000346                                                              16    7355
NP_000557                                                              16    7355
XP_006722804                                                           16    7355
XP_005245015                                                           16    7355
XP_005245014                                                           16    7355
NP_078966                                                              15    9605
NP_006107                                                              15    9605
NP_001483                                                              15    9605
NP_060501                                                              15    9605
NP_848611                                                              15    9605
NP_056453                                                              15    9605
NP_001017922                                                           15    9605
NP_061008                                                              15    9605
NP_955400                                                              15    9605
XP_006726571                                                           15    9605
XP_006726570                                                           15    9605
XP_003960511                                                           15    9605
XP_006717414                                                           15    9605
XP_005264894                                                           15    9605
XP_006710376                                                           15    9605
XP_005270472                                                           15    9605
XP_006710282                                                           15    9605
>NP_001006608
          Length = 1700

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>NP_955372
          Length = 1634

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>NP_055649
          Length = 1700

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005275724
          Length = 894

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005275722
          Length = 969

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005275721
          Length = 1018

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_006725345
          Length = 1600

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_006725344
          Length = 1606

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 509 SPSVTVQLL 517
>XP_005275719
          Length = 1625

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_006725343
          Length = 1635

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_006725342
          Length = 1651

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005275717
          Length = 1665

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005275716
          Length = 1676

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005257941
          Length = 969

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005257940
          Length = 1018

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_006722274
          Length = 1576

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_006722273
          Length = 1600

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005257939
          Length = 1606

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 509 SPSVTVQLL 517
>XP_006722272
          Length = 1635

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005257937
          Length = 1651

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005257936
          Length = 1665

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_005257935
          Length = 1676

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>XP_006722271
          Length = 1700

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SPSITLQVL 9
           SPS+T+Q+L
Sbjct: 603 SPSVTVQLL 611
>NP_004110
          Length = 993

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SPSITLQVL 9
          S SITLQVL
Sbjct: 86 SASITLQVL 94
>NP_003740
          Length = 1338

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   PSITLQVL 9
           PS+TLQ++
Sbjct: 236 PSVTLQLM 243
>XP_006711469
          Length = 357

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SPSITLQV 8
          SPS+TL+V
Sbjct: 15 SPSLTLKV 22
>XP_005245352
          Length = 357

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SPSITLQV 8
          SPS+TL+V
Sbjct: 15 SPSLTLKV 22
>NP_001276953
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPSITLQV 8
           SP +TLQ+
Sbjct: 166 SPEVTLQL 173
>NP_714912
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPSITLQV 8
           SP +TLQ+
Sbjct: 126 SPEVTLQL 133
>NP_001276952
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPSITLQV 8
           SP +TLQ+
Sbjct: 126 SPEVTLQL 133
>NP_005526
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPSITLQV 8
           SP +TLQ+
Sbjct: 126 SPEVTLQL 133
>NP_001171655
          Length = 400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SITLQVL 9
           S+TLQVL
Sbjct: 304 SVTLQVL 310
>NP_000346
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SITLQVL 9
           S+TLQVL
Sbjct: 331 SVTLQVL 337
>NP_000557
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPSITLQVL 9
           SP + LQVL
Sbjct: 273 SPELELQVL 281
>XP_006722804
          Length = 674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPSITLQV 8
           SP +TLQ+
Sbjct: 126 SPEVTLQL 133
>XP_005245015
          Length = 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPSITLQVL 9
           SP + LQVL
Sbjct: 181 SPELELQVL 189
>XP_005245014
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPSITLQVL 9
           SP + LQVL
Sbjct: 274 SPELELQVL 282
>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    SPSITL 6
            SPSITL
Sbjct: 2308 SPSITL 2313
>NP_006107
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SPSITLQ 7
           SP++TLQ
Sbjct: 438 SPTLTLQ 444
>NP_001483
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  SPSITLQ 7
          SP +TLQ
Sbjct: 82 SPGVTLQ 88
>NP_060501
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SPSITLQ 7
            +PS+TLQ
Sbjct: 1001 TPSLTLQ 1007
>NP_848611
          Length = 746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PSITLQVL 9
           P+I LQ+L
Sbjct: 423 PAIVLQIL 430
>NP_056453
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPSITLQV 8
           SP ITL++
Sbjct: 449 SPDITLKI 456
>NP_001017922
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SITLQVL 9
           S+TLQ+L
Sbjct: 108 SVTLQIL 114
>NP_061008
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SITLQVL 9
           S+TLQ+L
Sbjct: 108 SVTLQIL 114
>NP_955400
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPSITLQV 8
           SP ITL++
Sbjct: 441 SPDITLKI 448
>XP_006726571
          Length = 3681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SPSITLQVL 9
            SPS  LQVL
Sbjct: 1539 SPSPRLQVL 1547
>XP_006726570
          Length = 3722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SPSITLQVL 9
            SPS  LQVL
Sbjct: 1539 SPSPRLQVL 1547
>XP_003960511
          Length = 3722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SPSITLQVL 9
            SPS  LQVL
Sbjct: 1539 SPSPRLQVL 1547
>XP_006717414
          Length = 5100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SPSITLQVL 9
            SPS  LQVL
Sbjct: 2917 SPSPRLQVL 2925
>XP_005264894
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SPSITLQ 7
           +PS+TLQ
Sbjct: 920 TPSLTLQ 926
>XP_006710376
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SITLQVL 9
           S+TLQ+L
Sbjct: 108 SVTLQIL 114
>XP_005270472
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SITLQVL 9
           S+TLQ+L
Sbjct: 169 SVTLQIL 175
>XP_006710282
          Length = 2621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPSITLQVL 9
           SPS  LQVL
Sbjct: 438 SPSPRLQVL 446
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.128    0.320 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 642,304
Number of extensions: 1038
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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