Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001261                                                              19     869
XP_005271924                                                           19     869
XP_005271923                                                           19     869
NP_055105                                                              17    3301
XP_006717088                                                           17    3301
NP_006517                                                              16    5631
NP_003696                                                              16    5631
NP_001239586                                                           16    5631
XP_005260602                                                           16    5631
XP_006723938                                                           16    5631
XP_006713052                                                           16    5631
XP_006713051                                                           16    5631
XP_005246980                                                           16    5631
NP_003812                                                              15    9605
NP_055370                                                              15    9605
NP_065761                                                              15    9605
NP_071905                                                              15    9605
NP_064578                                                              15    9605
XP_006718702                                                           15    9605
XP_006718701                                                           15    9605
XP_006718700                                                           15    9605
XP_005274169                                                           15    9605
XP_005274166                                                           15    9605
XP_005274165                                                           15    9605
XP_005274163                                                           15    9605
XP_005252939                                                           15    9605
XP_005251149                                                           15    9605
>NP_001261
          Length = 1710

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SPSILVVQR 9
          SPSIL VQR
Sbjct: 90 SPSILAVQR 98
>XP_005271924
          Length = 1710

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SPSILVVQR 9
          SPSIL VQR
Sbjct: 90 SPSILAVQR 98
>XP_005271923
          Length = 1798

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SPSILVVQR 9
          SPSIL VQR
Sbjct: 90 SPSILAVQR 98
>NP_055105
          Length = 1098

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SPSILVVQ 8
           SPS+LVV+
Sbjct: 464 SPSVLVVE 471
>XP_006717088
          Length = 1024

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SPSILVVQ 8
           SPS+LVV+
Sbjct: 390 SPSVLVVE 397
>NP_006517
          Length = 1048

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SPSILVVQR 9
           SP++L VQ+
Sbjct: 980 SPNVLTVQK 988
>NP_003696
          Length = 678

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SPSILVVQ 8
           SPS+ VVQ
Sbjct: 662 SPSVAVVQ 669
>NP_001239586
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PSILVVQR 9
           PS++ VQR
Sbjct: 103 PSVIAVQR 110
>XP_005260602
          Length = 1061

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SPSILVVQR 9
           SP++L VQ+
Sbjct: 980 SPNVLTVQK 988
>XP_006723938
          Length = 1061

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SPSILVVQR 9
           SP++L VQ+
Sbjct: 980 SPNVLTVQK 988
>XP_006713052
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PSILVVQR 9
           PS++ VQR
Sbjct: 103 PSVIAVQR 110
>XP_006713051
          Length = 618

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PSILVVQR 9
           PS++ VQR
Sbjct: 103 PSVIAVQR 110
>XP_005246980
          Length = 661

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SPSILVVQ 8
           SPS+ VVQ
Sbjct: 645 SPSVAVVQ 652
>NP_003812
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   PSILVVQR 9
           P ILVV R
Sbjct: 521 PEILVVSR 528
>NP_055370
          Length = 1165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PSILVVQR 9
           P I+VV+R
Sbjct: 861 PKIIVVER 868
>NP_065761
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   PSILVVQR 9
           PS+LVV++
Sbjct: 545 PSLLVVEQ 552
>NP_071905
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPSILVVQR 9
          SP++LV  R
Sbjct: 3  SPAVLVTSR 11
>NP_064578
          Length = 1322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   PSILVVQR 9
           P+++VVQ+
Sbjct: 576 PNVIVVQK 583
>XP_006718702
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   PSILVVQR 9
           P+++VVQ+
Sbjct: 526 PNVIVVQK 533
>XP_006718701
          Length = 1309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   PSILVVQR 9
           P+++VVQ+
Sbjct: 577 PNVIVVQK 584
>XP_006718700
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   PSILVVQR 9
           P+++VVQ+
Sbjct: 591 PNVIVVQK 598
>XP_005274169
          Length = 1272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   PSILVVQR 9
           P+++VVQ+
Sbjct: 540 PNVIVVQK 547
>XP_005274166
          Length = 1323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   PSILVVQR 9
           P+++VVQ+
Sbjct: 591 PNVIVVQK 598
>XP_005274165
          Length = 1323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   PSILVVQR 9
           P+++VVQ+
Sbjct: 577 PNVIVVQK 584
>XP_005274163
          Length = 1337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   PSILVVQR 9
           P+++VVQ+
Sbjct: 591 PNVIVVQK 598
>XP_005252939
          Length = 1184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PSILVVQR 9
           P I+VV+R
Sbjct: 879 PKIIVVER 886
>XP_005251149
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   PSILVVQR 9
           P ILVV R
Sbjct: 384 PEILVVSR 391
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.133    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 611,732
Number of extensions: 962
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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