Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           19     665
NP_036462                                                              19     665
NP_001243397                                                           19     665
XP_005269721                                                           19     665
NP_001098674                                                           17    3301
XP_006711319                                                           17    3301
XP_006711318                                                           17    3301
XP_006711317                                                           17    3301
NP_001098673                                                           17    3301
NP_006729                                                              17    4312
NP_009131                                                              17    4312
XP_005254907                                                           17    4312
XP_005254906                                                           17    4312
XP_005254905                                                           17    4312
XP_005254904                                                           17    4312
XP_005254903                                                           17    4312
XP_005254902                                                           17    4312
XP_005254901                                                           17    4312
XP_005254900                                                           17    4312
XP_005254899                                                           17    4312
XP_005254898                                                           17    4312
XP_005254897                                                           17    4312
XP_006720441                                                           17    4312
XP_006720440                                                           17    4312
XP_006720439                                                           17    4312
XP_005254896                                                           17    4312
NP_001718                                                              16    5631
NP_065880                                                              16    5631
NP_001129392                                                           16    5631
NP_001193486                                                           16    5631
XP_005262522                                                           16    5631
XP_005262521                                                           16    5631
XP_005251580                                                           16    5631
NP_001136254                                                           16    7355
NP_690864                                                              16    7355
NP_065883                                                              16    7355
XP_005245423                                                           16    7355
XP_005245425                                                           16    7355
XP_005270794                                                           16    7355
NP_001159395                                                           15    9605
NP_000449                                                              15    9605
NP_066923                                                              15    9605
NP_001185918                                                           15    9605
NP_848594                                                              15    9605
XP_006723283                                                           15    9605
XP_005268181                                                           15    9605
XP_006719330                                                           15    9605
XP_005253911                                                           15    9605
XP_006719329                                                           15    9605
XP_006719328                                                           15    9605
XP_005249675                                                           15    9605
XP_006715711                                                           15    9605
NP_001138906                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SPDQSVISV 9
            SPDQS ISV
Sbjct: 1338 SPDQSAISV 1346
>NP_036462
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SPDQSVISV 9
            SPDQS ISV
Sbjct: 1630 SPDQSAISV 1638
>NP_001243397
          Length = 1890

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SPDQSVISV 9
            SPDQS ISV
Sbjct: 1447 SPDQSAISV 1455
>XP_005269721
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SPDQSVISV 9
            SPDQS ISV
Sbjct: 1630 SPDQSAISV 1638
>NP_001098674
          Length = 796

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPDQSVISV 9
           SPD+S +SV
Sbjct: 113 SPDESPVSV 121
>XP_006711319
          Length = 933

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPDQSVISV 9
           SPD+S +SV
Sbjct: 113 SPDESPVSV 121
>XP_006711318
          Length = 1039

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPDQSVISV 9
           SPD+S +SV
Sbjct: 113 SPDESPVSV 121
>XP_006711317
          Length = 1039

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPDQSVISV 9
           SPD+S +SV
Sbjct: 113 SPDESPVSV 121
>NP_001098673
          Length = 902

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPDQSVISV 9
           SPD+S +SV
Sbjct: 113 SPDESPVSV 121
>NP_006729
          Length = 2817

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>NP_009131
          Length = 2813

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_005254907
          Length = 2590

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 482 PDQAVIS 488
>XP_005254906
          Length = 2675

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 567 PDQAVIS 573
>XP_005254905
          Length = 2793

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_005254904
          Length = 2802

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_005254903
          Length = 2820

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_005254902
          Length = 2835

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_005254901
          Length = 2842

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_005254900
          Length = 2843

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_005254899
          Length = 2861

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_005254898
          Length = 2874

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_005254897
          Length = 2876

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_006720441
          Length = 2881

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_006720440
          Length = 2882

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_006720439
          Length = 2882

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>XP_005254896
          Length = 2883

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PDQSVIS 8
           PDQ+VIS
Sbjct: 775 PDQAVIS 781
>NP_001718
          Length = 399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SPDQSVISV 9
          SP+Q++IS+
Sbjct: 8  SPNQTLISI 16
>NP_065880
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SPD SV+ V
Sbjct: 315 SPDNSVVIV 323
>NP_001129392
          Length = 1165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SPD SV+ V
Sbjct: 315 SPDNSVVIV 323
>NP_001193486
          Length = 1386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SPD SV+ V
Sbjct: 315 SPDNSVVIV 323
>XP_005262522
          Length = 399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SPDQSVISV 9
          SP+Q++IS+
Sbjct: 8  SPNQTLISI 16
>XP_005262521
          Length = 399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SPDQSVISV 9
          SP+Q++IS+
Sbjct: 8  SPNQTLISI 16
>XP_005251580
          Length = 1422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SPD SV+ V
Sbjct: 314 SPDNSVVIV 322
>NP_001136254
          Length = 1481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    PDQSVISV 9
            PD +VISV
Sbjct: 1001 PDTAVISV 1008
>NP_690864
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    PDQSVISV 9
            PD +VISV
Sbjct: 1001 PDTAVISV 1008
>NP_065883
          Length = 1237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PDQSVISV 9
          PD SV+SV
Sbjct: 77 PDISVVSV 84
>XP_005245423
          Length = 1246

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PDQSVISV 9
          PD SV+SV
Sbjct: 86 PDISVVSV 93
>XP_005245425
          Length = 1299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PDQSVISV 9
           PD SV+SV
Sbjct: 139 PDISVVSV 146
>XP_005270794
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    PDQSVISV 9
            PD +VISV
Sbjct: 1001 PDTAVISV 1008
>NP_001159395
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SPD  +ISV
Sbjct: 371 SPDGKMISV 379
>NP_000449
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SPD  +ISV
Sbjct: 397 SPDGKMISV 405
>NP_066923
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PDQSVISV 9
           PD S++SV
Sbjct: 195 PDTSLVSV 202
>NP_001185918
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PDQSVISV 9
           PD S++SV
Sbjct: 144 PDTSLVSV 151
>NP_848594
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SP  S+ISV
Sbjct: 249 SPQSSMISV 257
>XP_006723283
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PDQSVISV 9
          PD SVIS+
Sbjct: 51 PDLSVISM 58
>XP_005268181
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPDQSVIS 8
           SP QSV++
Sbjct: 376 SPSQSVVT 383
>XP_006719330
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SP  S+ISV
Sbjct: 249 SPQSSMISV 257
>XP_005253911
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SP  S+ISV
Sbjct: 249 SPQSSMISV 257
>XP_006719329
          Length = 506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SP  S+ISV
Sbjct: 249 SPQSSMISV 257
>XP_006719328
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SPDQSVISV 9
           SP  S+ISV
Sbjct: 249 SPQSSMISV 257
>XP_005249675
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SPDQSVIS 8
          SPD  V+S
Sbjct: 51 SPDMGVVS 58
>XP_006715711
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SPDQSVIS 8
          SPD  V+S
Sbjct: 51 SPDMGVVS 58
>NP_001138906
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PDQSVISV 9
          PD SVIS+
Sbjct: 51 PDLSVISM 58
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.117    0.290 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 611,814
Number of extensions: 694
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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