Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              20     299
NP_001263689                                                           20     299
NP_001119584                                                           20     299
NP_001119586                                                           20     299
NP_001263625                                                           20     299
NP_001119590                                                           20     299
NP_001263690                                                           20     299
NP_001119585                                                           20     299
NP_001263624                                                           20     299
NP_002516                                                              17    2528
NP_001095132                                                           17    2528
NP_001229290                                                           17    2528
XP_005270960                                                           17    2528
NP_065890                                                              17    4312
NP_003651                                                              17    4312
XP_006723513                                                           17    4312
XP_005265403                                                           17    4312
NP_001164409                                                           16    5631
NP_057452                                                              16    5631
NP_001240318                                                           16    5631
NP_073617                                                              16    5631
XP_006722829                                                           16    5631
NP_005318                                                              16    7355
NP_001171634                                                           16    7355
NP_115971                                                              16    7355
NP_075463                                                              16    7355
NP_291020                                                              16    7355
NP_001184058                                                           16    7355
XP_006719812                                                           16    7355
XP_005263029                                                           16    7355
NP_001093261                                                           16    7355
NP_071433                                                              16    7355
NP_001073870                                                           16    7355
NP_000236                                                              15    9605
NP_001120972                                                           15    9605
NP_078966                                                              15    9605
NP_001728                                                              15    9605
NP_001012977                                                           15    9605
NP_001012976                                                           15    9605
NP_001012975                                                           15    9605
NP_001158027                                                           15    9605
NP_001158026                                                           15    9605
NP_001158025                                                           15    9605
NP_001158024                                                           15    9605
NP_001158023                                                           15    9605
NP_001158022                                                           15    9605
NP_001158021                                                           15    9605
NP_001158020                                                           15    9605
NP_001158019                                                           15    9605
NP_001158018                                                           15    9605
NP_001158017                                                           15    9605
NP_001158016                                                           15    9605
NP_001158014                                                           15    9605
NP_001158013                                                           15    9605
NP_001158012                                                           15    9605
NP_001158011                                                           15    9605
NP_001158010                                                           15    9605
NP_061132                                                              15    9605
NP_001243624                                                           15    9605
NP_001158009                                                           15    9605
XP_006723004                                                           15    9605
XP_006716054                                                           15    9605
XP_006716053                                                           15    9605
XP_006716052                                                           15    9605
XP_006716051                                                           15    9605
>NP_000537
          Length = 393

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SPALNKMF 8
           SPALNKMF
Sbjct: 127 SPALNKMF 134
>NP_001263689
          Length = 354

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  SPALNKMF 8
          SPALNKMF
Sbjct: 88 SPALNKMF 95
>NP_001119584
          Length = 393

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SPALNKMF 8
           SPALNKMF
Sbjct: 127 SPALNKMF 134
>NP_001119586
          Length = 341

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SPALNKMF 8
           SPALNKMF
Sbjct: 127 SPALNKMF 134
>NP_001263625
          Length = 302

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  SPALNKMF 8
          SPALNKMF
Sbjct: 88 SPALNKMF 95
>NP_001119590
          Length = 354

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  SPALNKMF 8
          SPALNKMF
Sbjct: 88 SPALNKMF 95
>NP_001263690
          Length = 354

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  SPALNKMF 8
          SPALNKMF
Sbjct: 88 SPALNKMF 95
>NP_001119585
          Length = 346

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SPALNKMF 8
           SPALNKMF
Sbjct: 127 SPALNKMF 134
>NP_001263624
          Length = 307

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  SPALNKMF 8
          SPALNKMF
Sbjct: 88 SPALNKMF 95
>NP_002516
          Length = 1219

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SPALNKMFR 9
           +PA NK++R
Sbjct: 490 TPAFNKLYR 498
>NP_001095132
          Length = 1151

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SPALNKMFR 9
           +PA NK++R
Sbjct: 422 TPAFNKLYR 430
>NP_001229290
          Length = 1087

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SPALNKMFR 9
           +PA NK++R
Sbjct: 358 TPAFNKLYR 366
>XP_005270960
          Length = 914

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SPALNKMFR 9
           +PA NK++R
Sbjct: 185 TPAFNKLYR 193
>NP_065890
          Length = 677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  PALNKMF 8
          PALN++F
Sbjct: 40 PALNRLF 46
>NP_003651
          Length = 1194

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SPALNKMFR 9
            SP+  KMFR
Sbjct: 1127 SPSWRKMFR 1135
>XP_006723513
          Length = 1185

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SPALNKMFR 9
            SP+  KMFR
Sbjct: 1118 SPSWRKMFR 1126
>XP_005265403
          Length = 707

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  PALNKMF 8
          PALN++F
Sbjct: 40 PALNRLF 46
>NP_001164409
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SPALNKMFR 9
           SP +N +FR
Sbjct: 419 SPVVNALFR 427
>NP_057452
          Length = 558

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SPALNKMFR 9
           SP +N +FR
Sbjct: 473 SPVVNALFR 481
>NP_001240318
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SPALNKMFR 9
           SP +N +FR
Sbjct: 345 SPVVNALFR 353
>NP_073617
          Length = 391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALNKMF 8
           ALNKMF
Sbjct: 362 ALNKMF 367
>XP_006722829
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SPALNKMFR 9
           SP +N +FR
Sbjct: 668 SPVVNALFR 676
>NP_005318
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SPALNKM 7
           SP+LNK+
Sbjct: 290 SPSLNKL 296
>NP_001171634
          Length = 331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SPALNKM 7
           SP+LNK+
Sbjct: 307 SPSLNKL 313
>NP_115971
          Length = 1604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SPALNKMF 8
            SP+ N+MF
Sbjct: 1017 SPSTNEMF 1024
>NP_075463
          Length = 3013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SPALNKM 7
            +P+LNKM
Sbjct: 2508 TPSLNKM 2514
>NP_291020
          Length = 156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SPALNKMF 8
          SP+L++MF
Sbjct: 44 SPSLDQMF 51
>NP_001184058
          Length = 156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SPALNKMF 8
          SP+L++MF
Sbjct: 44 SPSLDQMF 51
>XP_006719812
          Length = 3019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SPALNKM 7
            +P+LNKM
Sbjct: 2508 TPSLNKM 2514
>XP_005263029
          Length = 318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SPALNKM 7
           SP+LNK+
Sbjct: 294 SPSLNKL 300
>NP_001093261
          Length = 76

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SPALNKMF 8
          SP+L++MF
Sbjct: 44 SPSLDQMF 51
>NP_071433
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SPALNKM 7
          +PA+NKM
Sbjct: 75 TPAVNKM 81
>NP_001073870
          Length = 430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PALNKMFR 9
           P+LN +FR
Sbjct: 362 PSLNTVFR 369
>NP_000236
          Length = 1390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   PALNKMF 8
           PA+NK F
Sbjct: 628 PAMNKHF 634
>NP_001120972
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   PALNKMF 8
           PA+NK F
Sbjct: 628 PAMNKHF 634
>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     ALNKMFR 9
             ALN++FR
Sbjct: 14356 ALNQLFR 14362
>NP_001728
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  PALNKMFR 9
          P L +MFR
Sbjct: 56 PCLRQMFR 63
>NP_001012977
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001012976
          Length = 369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001012975
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158027
          Length = 356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158026
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158025
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158024
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158023
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158022
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158021
          Length = 547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158020
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158019
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158018
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158017
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158016
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158014
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158013
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158012
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158011
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001158010
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_061132
          Length = 854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>NP_001243624
          Length = 1177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SPALNKMF 8
           SP LN+M+
Sbjct: 521 SPTLNEMW 528
>NP_001158009
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SPALNKMFR 9
          SPA+  +FR
Sbjct: 58 SPAVGTLFR 66
>XP_006723004
          Length = 6443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ALNKMFR 9
            ALN++FR
Sbjct: 6292 ALNQLFR 6298
>XP_006716054
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   PALNKMF 8
           PA+NK F
Sbjct: 198 PAMNKHF 204
>XP_006716053
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   PALNKMF 8
           PA+NK F
Sbjct: 198 PAMNKHF 204
>XP_006716052
          Length = 1409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   PALNKMF 8
           PA+NK F
Sbjct: 647 PAMNKHF 653
>XP_006716051
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   PALNKMF 8
           PA+NK F
Sbjct: 647 PAMNKHF 653
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.132    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 580,051
Number of extensions: 813
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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