Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     299
NP_002802                                                              17    3301
NP_001278413                                                           17    4312
NP_004354                                                              17    4312
NP_001186317                                                           17    4312
NP_001129026                                                           17    4312
NP_001129027                                                           17    4312
NP_001239589                                                           17    4312
NP_001422                                                              17    4312
NP_056127                                                              17    4312
XP_005258472                                                           17    4312
XP_006715431                                                           17    4312
XP_006715430                                                           17    4312
XP_006715429                                                           17    4312
XP_006715428                                                           17    4312
XP_006715427                                                           17    4312
XP_006715426                                                           17    4312
XP_006715425                                                           17    4312
XP_006715424                                                           17    4312
XP_006715423                                                           17    4312
XP_006715422                                                           17    4312
XP_006715421                                                           17    4312
XP_006715420                                                           17    4312
XP_005266898                                                           17    4312
XP_005266897                                                           17    4312
XP_006715419                                                           17    4312
XP_006714407                                                           17    4312
XP_006714406                                                           17    4312
XP_005263347                                                           17    4312
XP_005263346                                                           17    4312
XP_005263345                                                           17    4312
XP_005263344                                                           17    4312
XP_005263343                                                           17    4312
XP_005263342                                                           17    4312
XP_005263341                                                           17    4312
XP_005263340                                                           17    4312
XP_005263339                                                           17    4312
NP_078898                                                              16    5631
NP_001268405                                                           16    5631
NP_004824                                                              16    5631
NP_002790                                                              16    5631
XP_006712814                                                           16    5631
XP_006712813                                                           16    5631
NP_115830                                                              16    7355
NP_001032961                                                           16    7355
NP_004188                                                              16    7355
NP_001002909                                                           16    7355
NP_057400                                                              16    7355
NP_116098                                                              16    7355
XP_006721846                                                           16    7355
XP_006721845                                                           16    7355
XP_006721844                                                           16    7355
XP_006718108                                                           16    7355
XP_005264025                                                           16    7355
XP_006712655                                                           16    7355
NP_003001                                                              15    9605
NP_001268364                                                           15    9605
NP_694960                                                              15    9605
NP_001131147                                                           15    9605
NP_848664                                                              15    9605
NP_006827                                                              15    9605
NP_065923                                                              15    9605
XP_006726423                                                           15    9605
XP_006726404                                                           15    9605
XP_006724953                                                           15    9605
XP_005256812                                                           15    9605
XP_006721631                                                           15    9605
XP_005256810                                                           15    9605
XP_005248314                                                           15    9605
XP_005248313                                                           15    9605
XP_005264814                                                           15    9605
XP_006711770                                                           15    9605
XP_005277402                                                           15    9605
XP_006711155                                                           15    9605
>NP_004295
          Length = 1620

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    NVATGRLP 9
            NVATGRLP
Sbjct: 1544 NVATGRLP 1551
>NP_002802
          Length = 324

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VATGRLP 9
           VATG+LP
Sbjct: 215 VATGKLP 221
>NP_001278413
          Length = 702

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SNVATGR 7
           SN+ATGR
Sbjct: 658 SNLATGR 664
>NP_004354
          Length = 702

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SNVATGR 7
           SN+ATGR
Sbjct: 658 SNLATGR 664
>NP_001186317
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>NP_001129026
          Length = 673

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>NP_001129027
          Length = 673

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>NP_001239589
          Length = 747

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>NP_001422
          Length = 1005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>NP_056127
          Length = 5005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_005258472
          Length = 420

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SNVATGR 7
           SN+ATGR
Sbjct: 376 SNLATGR 382
>XP_006715431
          Length = 673

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715430
          Length = 706

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715429
          Length = 730

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715428
          Length = 747

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715427
          Length = 838

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715426
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715425
          Length = 935

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715424
          Length = 1005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715423
          Length = 1023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715422
          Length = 1030

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715421
          Length = 1039

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715420
          Length = 1057

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_005266898
          Length = 1113

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_005266897
          Length = 1113

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006715419
          Length = 1113

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           ++A+GRLP
Sbjct: 320 DIASGRLP 327
>XP_006714407
          Length = 5004

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_006714406
          Length = 3680

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_005263347
          Length = 4640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_005263346
          Length = 4983

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_005263345
          Length = 4991

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_005263344
          Length = 5005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_005263343
          Length = 5009

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_005263342
          Length = 5025

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_005263341
          Length = 5026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_005263340
          Length = 5026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>XP_005263339
          Length = 5026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NVATGRL 8
           NV+TGRL
Sbjct: 206 NVSTGRL 212
>NP_078898
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NVATGRLP 9
           N+A G+LP
Sbjct: 748 NIALGQLP 755
>NP_001268405
          Length = 804

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NVATGRLP 9
           N+A G+LP
Sbjct: 705 NIALGQLP 712
>NP_004824
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  NVATGRL 8
          N+ATG+L
Sbjct: 34 NIATGKL 40
>NP_002790
          Length = 277

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NVATGRLP 9
           +++TGRLP
Sbjct: 110 SLSTGRLP 117
>XP_006712814
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NVATGRLP 9
           N+A G+LP
Sbjct: 428 NIALGQLP 435
>XP_006712813
          Length = 824

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NVATGRLP 9
           N+A G+LP
Sbjct: 725 NIALGQLP 732
>NP_115830
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SNVATGRLP 9
          +NVATG  P
Sbjct: 36 TNVATGAPP 44
>NP_001032961
          Length = 1250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SNVATGRLP 9
           SN  TGR P
Sbjct: 448 SNRGTGRAP 456
>NP_004188
          Length = 364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SNVATGRLP 9
          +NVATG  P
Sbjct: 36 TNVATGAPP 44
>NP_001002909
          Length = 1502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SNVATGR 7
            SN+ TGR
Sbjct: 1068 SNIGTGR 1074
>NP_057400
          Length = 1251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SNVATGRLP 9
           SN  TGR P
Sbjct: 448 SNRGTGRAP 456
>NP_116098
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NVATGRLP 9
           NVA  RLP
Sbjct: 378 NVAVDRLP 385
>XP_006721846
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   SNVATGR 7
           SN+ TGR
Sbjct: 990 SNIGTGR 996
>XP_006721845
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   SNVATGR 7
           SN+ TGR
Sbjct: 990 SNIGTGR 996
>XP_006721844
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   SNVATGR 7
           SN+ TGR
Sbjct: 990 SNIGTGR 996
>XP_006718108
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NVATGRLP 9
           NVA  RLP
Sbjct: 378 NVAVDRLP 385
>XP_005264025
          Length = 1181

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SNVATGRLP 9
           SN  TGR P
Sbjct: 378 SNRGTGRAP 386
>XP_006712655
          Length = 1251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SNVATGRLP 9
           SN  TGR P
Sbjct: 448 SNRGTGRAP 456
>NP_003001
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VATGRLP 9
           +ATGR P
Sbjct: 300 LATGRFP 306
>NP_001268364
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VATGRLP 9
           +ATGR P
Sbjct: 311 LATGRFP 317
>NP_694960
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NVATGRLP 9
          N +TG+LP
Sbjct: 46 NESTGQLP 53
>NP_001131147
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SNVATGRLP 9
           +N+AT  LP
Sbjct: 164 ANLATSHLP 172
>NP_848664
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VATGRLP 9
          +A+GRLP
Sbjct: 36 LASGRLP 42
>NP_006827
          Length = 2671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    NVATGRL 8
            NVA GRL
Sbjct: 2494 NVAPGRL 2500
>NP_065923
          Length = 1028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NVATGRL 8
           NVA GRL
Sbjct: 306 NVARGRL 312
>XP_006726423
          Length = 3768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ATGRLP 9
          +TGRLP
Sbjct: 5  STGRLP 10
>XP_006726404
          Length = 1355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ATGRLP 9
          +TGRLP
Sbjct: 5  STGRLP 10
>XP_006724953
          Length = 868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ATGRLP 9
          +TGRLP
Sbjct: 5  STGRLP 10
>XP_005256812
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VATGRLP 9
           +ATGR P
Sbjct: 154 LATGRFP 160
>XP_006721631
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VATGRLP 9
           +ATGR P
Sbjct: 182 LATGRFP 188
>XP_005256810
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VATGRLP 9
           +ATGR P
Sbjct: 182 LATGRFP 188
>XP_005248314
          Length = 113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VATGRLP 9
          +A+GRLP
Sbjct: 36 LASGRLP 42
>XP_005248313
          Length = 226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VATGRLP 9
          +A+GRLP
Sbjct: 36 LASGRLP 42
>XP_005264814
          Length = 1028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NVATGRL 8
           NVA GRL
Sbjct: 306 NVARGRL 312
>XP_006711770
          Length = 3768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ATGRLP 9
          +TGRLP
Sbjct: 5  STGRLP 10
>XP_005277402
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ATGRLP 9
          +TGRLP
Sbjct: 5  STGRLP 10
>XP_006711155
          Length = 1355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  ATGRLP 9
          +TGRLP
Sbjct: 5  STGRLP 10
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.126    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 482,075
Number of extensions: 662
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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