Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001156685                                                           19     665
NP_000133                                                              19     665
NP_075254                                                              19     665
XP_006713936                                                           19     665
XP_006713935                                                           19     665
XP_006713934                                                           19     665
XP_006713933                                                           19     665
XP_006713932                                                           19     665
XP_006713931                                                           19     665
NP_002829                                                              16    5631
XP_006711538                                                           16    5631
XP_006711536                                                           16    5631
NP_689842                                                              16    7355
NP_036553                                                              16    7355
NP_001035878                                                           16    7355
XP_006716794                                                           16    7355
XP_005251446                                                           16    7355
XP_005251445                                                           16    7355
XP_005251444                                                           16    7355
XP_005251443                                                           16    7355
NP_001195                                                              15    9605
NP_001184033                                                           15    9605
NP_005924                                                              15    9605
NP_079410                                                              15    9605
NP_060395                                                              15    9605
NP_056346                                                              15    9605
NP_001273506                                                           15    9605
NP_079286                                                              15    9605
XP_005256231                                                           15    9605
XP_005256229                                                           15    9605
XP_005256228                                                           15    9605
XP_005256227                                                           15    9605
XP_006721346                                                           15    9605
XP_005256226                                                           15    9605
XP_006721345                                                           15    9605
XP_006721344                                                           15    9605
XP_006721343                                                           15    9605
XP_005256225                                                           15    9605
XP_006718903                                                           15    9605
XP_006718902                                                           15    9605
XP_005273954                                                           15    9605
XP_006718558                                                           15    9605
XP_005273953                                                           15    9605
XP_005273952                                                           15    9605
XP_005273950                                                           15    9605
XP_006716870                                                           15    9605
XP_006716869                                                           15    9605
XP_006716868                                                           15    9605
XP_006716867                                                           15    9605
XP_006713142                                                           15    9605
XP_005265060                                                           15    9605
XP_005265059                                                           15    9605
XP_005265058                                                           15    9605
>NP_001156685
          Length = 808

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SNTSMSSNT 9
           SN SMSSNT
Sbjct: 429 SNASMSSNT 437
>NP_000133
          Length = 806

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SNTSMSSNT 9
           SN SMSSNT
Sbjct: 427 SNASMSSNT 435
>NP_075254
          Length = 694

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SNTSMSSNT 9
           SN SMSSNT
Sbjct: 315 SNASMSSNT 323
>XP_006713936
          Length = 807

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SNTSMSSNT 9
           SN SMSSNT
Sbjct: 427 SNASMSSNT 435
>XP_006713935
          Length = 807

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SNTSMSSNT 9
           SN SMSSNT
Sbjct: 428 SNASMSSNT 436
>XP_006713934
          Length = 809

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SNTSMSSNT 9
           SN SMSSNT
Sbjct: 429 SNASMSSNT 437
>XP_006713933
          Length = 810

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SNTSMSSNT 9
           SN SMSSNT
Sbjct: 430 SNASMSSNT 438
>XP_006713932
          Length = 810

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SNTSMSSNT 9
           SN SMSSNT
Sbjct: 431 SNASMSSNT 439
>XP_006713931
          Length = 811

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SNTSMSSNT 9
           SN SMSSNT
Sbjct: 431 SNASMSSNT 439
>NP_002829
          Length = 1306

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SNTSMSSNT 9
           SNT++++NT
Sbjct: 185 SNTTITANT 193
>XP_006711538
          Length = 1189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SNTSMSSNT 9
          SNT++++NT
Sbjct: 68 SNTTITANT 76
>XP_006711536
          Length = 1240

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SNTSMSSNT 9
           SNT++++NT
Sbjct: 119 SNTTITANT 127
>NP_689842
          Length = 775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TSMSSNT 9
           TSMSSN+
Sbjct: 103 TSMSSNS 109
>NP_036553
          Length = 1914

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SNTSMSSN 8
            SN+S SSN
Sbjct: 1799 SNSSQSSN 1806
>NP_001035878
          Length = 930

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TSMSSNT 9
           TSMSSN+
Sbjct: 258 TSMSSNS 264
>XP_006716794
          Length = 572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TSMSSNT 9
           TSMSSN+
Sbjct: 258 TSMSSNS 264
>XP_005251446
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TSMSSNT 9
           TSMSSN+
Sbjct: 258 TSMSSNS 264
>XP_005251445
          Length = 708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TSMSSNT 9
          TSMSSN+
Sbjct: 36 TSMSSNS 42
>XP_005251444
          Length = 708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TSMSSNT 9
          TSMSSN+
Sbjct: 36 TSMSSNS 42
>XP_005251443
          Length = 775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TSMSSNT 9
           TSMSSN+
Sbjct: 103 TSMSSNS 109
>NP_001195
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SNTSMSSNT 9
           S TS+S+NT
Sbjct: 604 SVTSLSTNT 612
>NP_001184033
          Length = 3972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    NTSMSSN 8
            NTS SSN
Sbjct: 2262 NTSTSSN 2268
>NP_005924
          Length = 3969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    NTSMSSN 8
            NTS SSN
Sbjct: 2259 NTSTSSN 2265
>NP_079410
          Length = 2881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>NP_060395
          Length = 1909

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    NTSMSS 7
            NTSMSS
Sbjct: 1473 NTSMSS 1478
>NP_056346
          Length = 1963

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSMSSNT 9
           NT +S NT
Sbjct: 711 NTKLSGNT 718
>NP_001273506
          Length = 2353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSMSSNT 9
           NT +S NT
Sbjct: 711 NTKLSGNT 718
>NP_079286
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TSMSSN 8
           TSMSSN
Sbjct: 414 TSMSSN 419
>XP_005256231
          Length = 2573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>XP_005256229
          Length = 2881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>XP_005256228
          Length = 2882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>XP_005256227
          Length = 2897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>XP_006721346
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>XP_005256226
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>XP_006721345
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>XP_006721344
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>XP_006721343
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>XP_005256225
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSMSSN 8
           NTS++SN
Sbjct: 329 NTSLNSN 335
>XP_006718903
          Length = 2673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NTSMSSN 8
           NTS SSN
Sbjct: 963 NTSTSSN 969
>XP_006718902
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    NTSMSSN 8
            NTS SSN
Sbjct: 1254 NTSTSSN 1260
>XP_005273954
          Length = 1676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSMSSNT 9
           NT +S NT
Sbjct: 711 NTKLSGNT 718
>XP_006718558
          Length = 1841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSMSSNT 9
           NT +S NT
Sbjct: 198 NTKLSGNT 205
>XP_005273953
          Length = 2171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSMSSNT 9
           NT +S NT
Sbjct: 528 NTKLSGNT 535
>XP_005273952
          Length = 2245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSMSSNT 9
           NT +S NT
Sbjct: 602 NTKLSGNT 609
>XP_005273950
          Length = 2354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSMSSNT 9
           NT +S NT
Sbjct: 711 NTKLSGNT 718
>XP_006716870
          Length = 1456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    NTSMSS 7
            NTSMSS
Sbjct: 1020 NTSMSS 1025
>XP_006716869
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    NTSMSS 7
            NTSMSS
Sbjct: 1286 NTSMSS 1291
>XP_006716868
          Length = 1894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    NTSMSS 7
            NTSMSS
Sbjct: 1522 NTSMSS 1527
>XP_006716867
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    NTSMSS 7
            NTSMSS
Sbjct: 1522 NTSMSS 1527
>XP_006713142
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TSMSSN 8
           TSMSSN
Sbjct: 359 TSMSSN 364
>XP_005265060
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TSMSSN 8
           TSMSSN
Sbjct: 479 TSMSSN 484
>XP_005265059
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TSMSSN 8
           TSMSSN
Sbjct: 479 TSMSSN 484
>XP_005265058
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TSMSSN 8
           TSMSSN
Sbjct: 484 TSMSSN 489
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.263   0.0758    0.161 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 287,464
Number of extensions: 449
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 19 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.4 bits)
S2: 28 (15.4 bits)

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