Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_001185763                                                           19     665
NP_055459                                                              19     665
NP_001002811                                                           19     665
NP_001002812                                                           19     665
XP_006726410                                                           19     665
XP_006711719                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711712                                                           19     665
XP_006711711                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
XP_005277503                                                           19     665
XP_005273038                                                           19     665
XP_006711708                                                           19     665
XP_005277500                                                           19     665
XP_006711707                                                           19     665
XP_005277499                                                           19     665
XP_006711706                                                           19     665
XP_006711705                                                           19     665
XP_006711164                                                           19     665
NP_112576                                                              17    4312
NP_001035351                                                           16    5631
NP_001035350                                                           16    5631
NP_001273975                                                           16    5631
NP_001273974                                                           16    5631
NP_064530                                                              16    5631
XP_005252157                                                           16    5631
XP_006717254                                                           16    5631
XP_005252155                                                           16    5631
XP_006717253                                                           16    5631
XP_006717252                                                           16    5631
XP_006717251                                                           16    5631
XP_005262843                                                           16    5631
XP_005262842                                                           16    5631
NP_001073947                                                           16    5631
NP_001193581                                                           16    7355
NP_036424                                                              16    7355
NP_031370                                                              16    7355
NP_001193582                                                           16    7355
NP_057093                                                              16    7355
NP_001193580                                                           16    7355
NP_001269263                                                           16    7355
NP_872198                                                              16    7355
NP_004746                                                              16    7355
NP_001269264                                                           16    7355
NP_001245257                                                           16    7355
XP_006722776                                                           16    7355
XP_006717338                                                           16    7355
XP_006717337                                                           16    7355
XP_006717336                                                           16    7355
XP_006710736                                                           16    7355
XP_006710735                                                           16    7355
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 763 SNQQAEVT 770
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 697 SNQQAEVT 704
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 697 SNQQAEVT 704
>NP_001002811
          Length = 1132

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>NP_001002812
          Length = 969

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 697 SNQQAEVT 704
>XP_006726410
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 772 SNQQAEVT 779
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 763 SNQQAEVT 770
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 763 SNQQAEVT 770
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 763 SNQQAEVT 770
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 697 SNQQAEVT 704
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 697 SNQQAEVT 704
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 700 SNQQAEVT 707
>XP_006711712
          Length = 2473

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>XP_006711711
          Length = 2482

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 763 SNQQAEVT 770
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 763 SNQQAEVT 770
>XP_005277503
          Length = 2498

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>XP_005273038
          Length = 2509

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>XP_006711708
          Length = 2512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>XP_005277500
          Length = 2525

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>XP_006711707
          Length = 2553

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>XP_005277499
          Length = 2561

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>XP_006711706
          Length = 2591

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>XP_006711705
          Length = 2592

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 860 SNQQAEVT 867
>XP_006711164
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SNQQAEVT 8
           SNQQAEVT
Sbjct: 772 SNQQAEVT 779
>NP_112576
          Length = 93

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  NQQAEVTR 9
          +QQ+EVTR
Sbjct: 19 SQQSEVTR 26
>NP_001035351
          Length = 783

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SNQQAEVT 8
           +N QAEVT
Sbjct: 676 NNMQAEVT 683
>NP_001035350
          Length = 766

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SNQQAEVT 8
           +N QAEVT
Sbjct: 659 NNMQAEVT 666
>NP_001273975
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAEVTR
Sbjct: 229 DRQAEVTR 236
>NP_001273974
          Length = 404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAEVTR
Sbjct: 233 DRQAEVTR 240
>NP_064530
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAEVTR
Sbjct: 229 DRQAEVTR 236
>XP_005252157
          Length = 379

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAEVTR
Sbjct: 208 DRQAEVTR 215
>XP_006717254
          Length = 399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAEVTR
Sbjct: 233 DRQAEVTR 240
>XP_005252155
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAEVTR
Sbjct: 229 DRQAEVTR 236
>XP_006717253
          Length = 423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAEVTR
Sbjct: 257 DRQAEVTR 264
>XP_006717252
          Length = 424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAEVTR
Sbjct: 253 DRQAEVTR 260
>XP_006717251
          Length = 428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAEVTR
Sbjct: 257 DRQAEVTR 264
>XP_005262843
          Length = 765

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SNQQAEVT 8
           +N QAEVT
Sbjct: 658 NNMQAEVT 665
>XP_005262842
          Length = 782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SNQQAEVT 8
           +N QAEVT
Sbjct: 675 NNMQAEVT 682
>NP_001073947
          Length = 514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  QQAEVTR 9
          +QAEVTR
Sbjct: 45 EQAEVTR 51
>NP_001193581
          Length = 386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAE+TR
Sbjct: 224 DRQAEITR 231
>NP_036424
          Length = 1136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SNQQAEV 7
           SNQ+AEV
Sbjct: 989 SNQRAEV 995
>NP_031370
          Length = 905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  NQQAEVTR 9
          N+Q+++TR
Sbjct: 44 NEQSQITR 51
>NP_001193582
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAE+TR
Sbjct: 103 DRQAEITR 110
>NP_057093
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAE+TR
Sbjct: 203 DRQAEITR 210
>NP_001193580
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAE+TR
Sbjct: 232 DRQAEITR 239
>NP_001269263
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SNQQAEV 7
           SNQ+AEV
Sbjct: 624 SNQRAEV 630
>NP_872198
          Length = 549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NQQAEVTR 9
           N QAE++R
Sbjct: 262 NSQAEISR 269
>NP_004746
          Length = 802

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NQQAEVTR 9
           N QAE++R
Sbjct: 262 NSQAEISR 269
>NP_001269264
          Length = 1019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SNQQAEV 7
           SNQ+AEV
Sbjct: 872 SNQRAEV 878
>NP_001245257
          Length = 1152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SNQQAEV 7
            SNQ+AEV
Sbjct: 1005 SNQRAEV 1011
>XP_006722776
          Length = 1164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SNQQAEV 7
            SNQ+AEV
Sbjct: 1017 SNQRAEV 1023
>XP_006717338
          Length = 868

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  NQQAEVTR 9
          N+Q+++TR
Sbjct: 71 NEQSQITR 78
>XP_006717337
          Length = 876

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  NQQAEVTR 9
          N+Q+++TR
Sbjct: 71 NEQSQITR 78
>XP_006717336
          Length = 932

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  NQQAEVTR 9
          N+Q+++TR
Sbjct: 71 NEQSQITR 78
>XP_006710736
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAE+TR
Sbjct: 140 DRQAEITR 147
>XP_006710735
          Length = 402

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NQQAEVTR 9
           ++QAE+TR
Sbjct: 240 DRQAEITR 247
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.292    0.101    0.230 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 361,727
Number of extensions: 460
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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