Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     665
NP_001035957                                                           19     665
XP_006721991                                                           19     665
XP_006721990                                                           19     665
XP_006721989                                                           19     665
XP_005258041                                                           19     665
XP_006721988                                                           19     665
XP_006721987                                                           19     665
XP_006721986                                                           19     665
XP_005258040                                                           19     665
XP_006721985                                                           19     665
NP_055730                                                              17    4312
NP_001242982                                                           17    4312
XP_006717494                                                           17    4312
XP_006717493                                                           17    4312
XP_006717491                                                           17    4312
XP_006717490                                                           17    4312
XP_006717489                                                           17    4312
XP_006717488                                                           17    4312
XP_006717487                                                           17    4312
XP_006717486                                                           17    4312
NP_001243839                                                           16    5631
NP_004719                                                              16    5631
XP_006719560                                                           16    5631
XP_005269075                                                           16    5631
NP_060458                                                              16    5631
NP_004659                                                              16    7355
NP_003125                                                              16    7355
NP_001253981                                                           16    7355
XP_005257983                                                           16    7355
XP_006716232                                                           16    7355
XP_006716231                                                           16    7355
NP_775259                                                              16    7355
NP_001028748                                                           16    7355
NP_001243092                                                           15    9605
NP_001243095                                                           15    9605
NP_001157                                                              15    9605
NP_653309                                                              15    9605
NP_114425                                                              15    9605
NP_003667                                                              15    9605
XP_006711902                                                           15    9605
NP_061720                                                              15    9605
>NP_000258
          Length = 2818

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1150 SNLLNANV 1157
>NP_001035957
          Length = 2839

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1150 SNLLNANV 1157
>XP_006721991
          Length = 1632

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1160 SNLLNANV 1167
>XP_006721990
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1160 SNLLNANV 1167
>XP_006721989
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1160 SNLLNANV 1167
>XP_005258041
          Length = 2836

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1150 SNLLNANV 1157
>XP_006721988
          Length = 2846

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1160 SNLLNANV 1167
>XP_006721987
          Length = 2849

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1160 SNLLNANV 1167
>XP_006721986
          Length = 2854

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1147 SNLLNANV 1154
>XP_005258040
          Length = 2857

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1150 SNLLNANV 1157
>XP_006721985
          Length = 2867

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SNLLNANV 8
            SNLLNANV
Sbjct: 1160 SNLLNANV 1167
>NP_055730
          Length = 1710

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    NLLNANV 8
            NLLNAN+
Sbjct: 1318 NLLNANL 1324
>NP_001242982
          Length = 1709

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    NLLNANV 8
            NLLNAN+
Sbjct: 1317 NLLNANL 1323
>XP_006717494
          Length = 1571

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    NLLNANV 8
            NLLNAN+
Sbjct: 1179 NLLNANL 1185
>XP_006717493
          Length = 1610

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    NLLNANV 8
            NLLNAN+
Sbjct: 1218 NLLNANL 1224
>XP_006717491
          Length = 1677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    NLLNANV 8
            NLLNAN+
Sbjct: 1285 NLLNANL 1291
>XP_006717490
          Length = 1791

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    NLLNANV 8
            NLLNAN+
Sbjct: 1399 NLLNANL 1405
>XP_006717489
          Length = 1945

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    NLLNANV 8
            NLLNAN+
Sbjct: 1680 NLLNANL 1686
>XP_006717488
          Length = 2031

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    NLLNANV 8
            NLLNAN+
Sbjct: 1680 NLLNANL 1686
>XP_006717487
          Length = 2071

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    NLLNANV 8
            NLLNAN+
Sbjct: 1679 NLLNANL 1685
>XP_006717486
          Length = 2072

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    NLLNANV 8
            NLLNAN+
Sbjct: 1680 NLLNANL 1686
>NP_001243839
          Length = 715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NLLNANVG 9
           +L+N+NVG
Sbjct: 560 SLINSNVG 567
>NP_004719
          Length = 783

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NLLNANVG 9
           +L+N+NVG
Sbjct: 628 SLINSNVG 635
>XP_006719560
          Length = 826

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SNLLNANVG 9
           +N LNAN+G
Sbjct: 667 TNGLNANMG 675
>XP_005269075
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SNLLNANVG 9
           +N LNAN+G
Sbjct: 770 TNGLNANMG 778
>NP_060458
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SNLLNANVG 9
           +N LNAN+G
Sbjct: 770 TNGLNANMG 778
>NP_004659
          Length = 1857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NLLNANVG 9
           NL+N N G
Sbjct: 143 NLVNTNAG 150
>NP_003125
          Length = 136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SNLLNANV 8
          SNLL AN+
Sbjct: 84 SNLLRANM 91
>NP_001253981
          Length = 929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NLLNANV 8
           NLLN NV
Sbjct: 301 NLLNKNV 307
>XP_005257983
          Length = 850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NLLNANV 8
           NLLN NV
Sbjct: 301 NLLNKNV 307
>XP_006716232
          Length = 2753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NLLNANVG 9
           NL+N N G
Sbjct: 143 NLVNTNAG 150
>XP_006716231
          Length = 2753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NLLNANVG 9
           NL+N N G
Sbjct: 143 NLVNTNAG 150
>NP_775259
          Length = 931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NLLNANV 8
           NLLN NV
Sbjct: 301 NLLNKNV 307
>NP_001028748
          Length = 929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NLLNANV 8
           NLLN NV
Sbjct: 301 NLLNKNV 307
>NP_001243092
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NLLNANV 8
           NLL ANV
Sbjct: 481 NLLKANV 487
>NP_001243095
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NLLNANV 8
           NLL ANV
Sbjct: 432 NLLKANV 438
>NP_001157
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NLLNANV 8
           NLL ANV
Sbjct: 481 NLLKANV 487
>NP_653309
          Length = 1434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NLLNANV 8
           NLLN N+
Sbjct: 830 NLLNLNI 836
>NP_114425
          Length = 130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SNLLNANVG 9
          SN+L A+VG
Sbjct: 75 SNILLASVG 83
>NP_003667
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NLLNANVG 9
           NLL  NVG
Sbjct: 250 NLLTFNVG 257
>XP_006711902
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NLLNANVG 9
           NLL  NVG
Sbjct: 250 NLLTFNVG 257
>NP_061720
          Length = 4024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    SNLLNA 6
            SNLLNA
Sbjct: 2413 SNLLNA 2418
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.124    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 391,198
Number of extensions: 656
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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