Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_859075                                                              16    5631
NP_001191675                                                           16    5631
NP_001191674                                                           16    5631
NP_001191673                                                           16    5631
NP_004053                                                              16    5631
XP_005255827                                                           16    5631
XP_005255826                                                           16    5631
XP_005255825                                                           16    5631
XP_006719432                                                           16    5631
XP_006719431                                                           16    5631
NP_001185951                                                           16    7355
NP_055526                                                              16    7355
NP_001229800                                                           16    7355
NP_001229799                                                           16    7355
NP_001229798                                                           16    7355
NP_001035243                                                           16    7355
NP_001229797                                                           16    7355
XP_006721168                                                           16    7355
XP_005255778                                                           16    7355
XP_005255776                                                           16    7355
XP_006719828                                                           16    7355
NP_653196                                                              16    7355
NP_001180237                                                           15    9605
NP_055918                                                              15    9605
NP_005294                                                              15    9605
XP_006711055                                                           15    9605
XP_005246079                                                           15    9605
XP_005246078                                                           15    9605
XP_006711050                                                           15    9605
>NP_859075
          Length = 283

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SMPLKAT 9
          S+PLKAT
Sbjct: 27 SVPLKAT 33
>NP_001191675
          Length = 732

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SMPLKAT 9
           S+PLKAT
Sbjct: 725 SVPLKAT 731
>NP_001191674
          Length = 790

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SMPLKAT 9
           S+PLKAT
Sbjct: 783 SVPLKAT 789
>NP_001191673
          Length = 807

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SMPLKAT 9
           S+PLKAT
Sbjct: 800 SVPLKAT 806
>NP_004053
          Length = 829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SMPLKAT 9
           S+PLKAT
Sbjct: 822 SVPLKAT 828
>XP_005255827
          Length = 651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SMPLKAT 9
           S+PLKAT
Sbjct: 644 SVPLKAT 650
>XP_005255826
          Length = 766

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SMPLKAT 9
           S+PLKAT
Sbjct: 759 SVPLKAT 765
>XP_005255825
          Length = 829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SMPLKAT 9
           S+PLKAT
Sbjct: 822 SVPLKAT 828
>XP_006719432
          Length = 283

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SMPLKAT 9
          S+PLKAT
Sbjct: 27 SVPLKAT 33
>XP_006719431
          Length = 283

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SMPLKAT 9
          S+PLKAT
Sbjct: 27 SVPLKAT 33
>NP_001185951
          Length = 1012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SMSMPLKAT 9
           SMSMP+ A+
Sbjct: 311 SMSMPVLAS 319
>NP_055526
          Length = 991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SMSMPLKAT 9
           SMSMP+ A+
Sbjct: 311 SMSMPVLAS 319
>NP_001229800
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SMSMPLKAT 9
           S+  PLKAT
Sbjct: 205 SIRQPLKAT 213
>NP_001229799
          Length = 191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SMSMPLKAT 9
           S+  PLKAT
Sbjct: 92  SIRQPLKAT 100
>NP_001229798
          Length = 191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SMSMPLKAT 9
           S+  PLKAT
Sbjct: 92  SIRQPLKAT 100
>NP_001035243
          Length = 426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SMSMPLKAT 9
           S+  PLKAT
Sbjct: 327 SIRQPLKAT 335
>NP_001229797
          Length = 590

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SMSMPLKAT 9
           S+  PLKAT
Sbjct: 491 SIRQPLKAT 499
>XP_006721168
          Length = 971

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SMSMPLKAT 9
           SMSMP+ A+
Sbjct: 311 SMSMPVLAS 319
>XP_005255778
          Length = 991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SMSMPLKAT 9
           SMSMP+ A+
Sbjct: 311 SMSMPVLAS 319
>XP_005255776
          Length = 1012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SMSMPLKAT 9
           SMSMP+ A+
Sbjct: 311 SMSMPVLAS 319
>XP_006719828
          Length = 640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SMSMPLKAT 9
           S+  PLKAT
Sbjct: 541 SIRQPLKAT 549
>NP_653196
          Length = 305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SMSMPLKAT 9
           S+  PLKAT
Sbjct: 206 SIRQPLKAT 214
>NP_001180237
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SMSMPLKAT 9
           S S+PLKA+
Sbjct: 159 SPSVPLKAS 167
>NP_055918
          Length = 1925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SMSMPLKAT 9
           S+  PLKAT
Sbjct: 455 SILQPLKAT 463
>NP_005294
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SMSMPLKA 8
          ++S+PLKA
Sbjct: 56 TVSLPLKA 63
>XP_006711055
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SMSMPLKAT 9
           S S+PLKA+
Sbjct: 191 SPSVPLKAS 199
>XP_005246079
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SMSMPLKAT 9
           S S+PLKA+
Sbjct: 191 SPSVPLKAS 199
>XP_005246078
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SMSMPLKAT 9
           S S+PLKA+
Sbjct: 159 SPSVPLKAS 167
>XP_006711050
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SMSMPLKAT 9
           S S+PLKA+
Sbjct: 191 SPSVPLKAS 199
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.108    0.274 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 427,739
Number of extensions: 301
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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