Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1482
NP_001138390                                                           18    1482
NP_001138386                                                           18    1482
NP_001138387                                                           18    1482
NP_000132                                                              18    1482
NP_075259                                                              18    1482
NP_001138388                                                           18    1482
NP_001138391                                                           18    1482
NP_001138385                                                           18    1482
NP_075418                                                              18    1482
XP_006717776                                                           18    1482
XP_006717775                                                           18    1482
XP_006717774                                                           18    1482
XP_006717773                                                           18    1482
XP_006717772                                                           18    1482
XP_006717771                                                           18    1482
NP_001157745                                                           15    9605
NP_995328                                                              15    9605
NP_066363                                                              15    9605
XP_006724594                                                           15    9605
XP_006724593                                                           15    9605
XP_006723899                                                           15    9605
XP_005254311                                                           15    9605
XP_006720508                                                           15    9605
XP_006720507                                                           15    9605
XP_005254309                                                           15    9605
XP_005254306                                                           15    9605
XP_005254305                                                           15    9605
XP_005254304                                                           15    9605
XP_005254303                                                           15    9605
XP_006720506                                                           15    9605
XP_005254302                                                           15    9605
XP_005254301                                                           15    9605
XP_006720505                                                           15    9605
XP_005254300                                                           15    9605
NP_001073369                                                           15    9605
>NP_001138389
          Length = 705

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 10 LVVVTMAT 17
>NP_001138390
          Length = 704

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 10 LVVVTMAT 17
>NP_001138386
          Length = 709

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 10 LVVVTMAT 17
>NP_001138387
          Length = 707

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 10 LVVVTMAT 17
>NP_000132
          Length = 821

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 10 LVVVTMAT 17
>NP_075259
          Length = 822

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 10 LVVVTMAT 17
>NP_001138388
          Length = 706

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 10 LVVVTMAT 17
>NP_001138391
          Length = 680

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 10 LVVVTMAT 17
>NP_001138385
          Length = 769

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 10 LVVVTMAT 17
>NP_075418
          Length = 732

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 10 LVVVTMAT 17
>XP_006717776
          Length = 806

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 29 LVVVTMAT 36
>XP_006717775
          Length = 726

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 29 LVVVTMAT 36
>XP_006717774
          Length = 752

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 29 LVVVTMAT 36
>XP_006717773
          Length = 807

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 29 LVVVTMAT 36
>XP_006717772
          Length = 838

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 29 LVVVTMAT 36
>XP_006717771
          Length = 839

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVVVTMAT 9
          LVVVTMAT
Sbjct: 29 LVVVTMAT 36
>NP_001157745
          Length = 3065

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1697 SLVVVTAA 1704
>NP_995328
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VVVTMAT 9
          VVVT+AT
Sbjct: 7  VVVTLAT 13
>NP_066363
          Length = 1918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVVVTMAT 9
           S VV+T+AT
Sbjct: 158 SEVVITLAT 166
>XP_006724594
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VVVTMAT 9
          VVVT+AT
Sbjct: 7  VVVTLAT 13
>XP_006724593
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VVVTMAT 9
          VVVT+AT
Sbjct: 7  VVVTLAT 13
>XP_006723899
          Length = 1918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVVVTMAT 9
           S VV+T+AT
Sbjct: 158 SEVVITLAT 166
>XP_005254311
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLVVVTMA 8
           SLVVVT A
Sbjct: 258 SLVVVTAA 265
>XP_006720508
          Length = 2658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1289 SLVVVTAA 1296
>XP_006720507
          Length = 2763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1394 SLVVVTAA 1401
>XP_005254309
          Length = 2956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1587 SLVVVTAA 1594
>XP_005254306
          Length = 3066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1697 SLVVVTAA 1704
>XP_005254305
          Length = 3114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1746 SLVVVTAA 1753
>XP_005254304
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1746 SLVVVTAA 1753
>XP_005254303
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1746 SLVVVTAA 1753
>XP_006720506
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1746 SLVVVTAA 1753
>XP_005254302
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1746 SLVVVTAA 1753
>XP_005254301
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1746 SLVVVTAA 1753
>XP_006720505
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1746 SLVVVTAA 1753
>XP_005254300
          Length = 3115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLVVVTMA 8
            SLVVVT A
Sbjct: 1746 SLVVVTAA 1753
>NP_001073369
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VVVTMAT 9
          VVVT+AT
Sbjct: 7  VVVTLAT 13
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.121    0.272 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 206,542
Number of extensions: 188
Number of successful extensions: 36
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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