Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              18    1935
NP_001071643                                                           17    4312
NP_001071644                                                           17    4312
NP_001071645                                                           17    4312
NP_001071642                                                           17    4312
NP_004946                                                              17    4312
XP_005248939                                                           17    4312
XP_005248938                                                           17    4312
XP_005248936                                                           17    4312
XP_005248937                                                           17    4312
XP_005248935                                                           17    4312
XP_005248933                                                           17    4312
XP_005248932                                                           17    4312
NP_060224                                                              16    7355
XP_005249256                                                           16    7355
XP_006715189                                                           16    7355
XP_006715188                                                           16    7355
NP_683765                                                              16    7355
NP_997175                                                              15    9605
NP_997180                                                              15    9605
NP_997179                                                              15    9605
NP_997176                                                              15    9605
NP_066368                                                              15    9605
NP_005520                                                              15    9605
NP_036516                                                              15    9605
NP_055887                                                              15    9605
NP_078942                                                              15    9605
XP_005260259                                                           15    9605
XP_006720746                                                           15    9605
XP_005254721                                                           15    9605
XP_005247534                                                           15    9605
XP_005247533                                                           15    9605
XP_005247532                                                           15    9605
XP_005247531                                                           15    9605
XP_005247530                                                           15    9605
XP_005247529                                                           15    9605
XP_005247528                                                           15    9605
XP_005247527                                                           15    9605
XP_006713704                                                           15    9605
XP_006713703                                                           15    9605
XP_005247526                                                           15    9605
XP_005247525                                                           15    9605
XP_005247524                                                           15    9605
XP_005247523                                                           15    9605
XP_005247522                                                           15    9605
XP_005247521                                                           15    9605
XP_005247520                                                           15    9605
XP_005247519                                                           15    9605
XP_005247518                                                           15    9605
XP_005247517                                                           15    9605
XP_006713702                                                           15    9605
XP_005247516                                                           15    9605
XP_005247515                                                           15    9605
XP_005247514                                                           15    9605
XP_006710661                                                           15    9605
XP_005245920                                                           15    9605
XP_006710660                                                           15    9605
XP_006710659                                                           15    9605
XP_006710658                                                           15    9605
XP_006710657                                                           15    9605
>NP_115927
          Length = 1321

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLVTAELAP 9
           S VTAELAP
Sbjct: 847 SPVTAELAP 855
>NP_001071643
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLVTAELA 8
          SLVTAEL+
Sbjct: 50 SLVTAELS 57
>NP_001071644
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLVTAELA 8
          SLVTAEL+
Sbjct: 50 SLVTAELS 57
>NP_001071645
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLVTAELA 8
          SLVTAEL+
Sbjct: 50 SLVTAELS 57
>NP_001071642
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLVTAELA 8
          SLVTAEL+
Sbjct: 50 SLVTAELS 57
>NP_004946
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLVTAELA 8
          SLVTAEL+
Sbjct: 50 SLVTAELS 57
>XP_005248939
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLVTAELA 8
          SLVTAEL+
Sbjct: 50 SLVTAELS 57
>XP_005248938
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLVTAELA 8
          SLVTAEL+
Sbjct: 50 SLVTAELS 57
>XP_005248936
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLVTAELA 8
          SLVTAEL+
Sbjct: 50 SLVTAELS 57
>XP_005248937
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLVTAELA 8
          SLVTAEL+
Sbjct: 50 SLVTAELS 57
>XP_005248935
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLVTAELA 8
          SLVTAEL+
Sbjct: 50 SLVTAELS 57
>XP_005248933
          Length = 499

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SLVTAELA 8
           SLVTAEL+
Sbjct: 93  SLVTAELS 100
>XP_005248932
          Length = 535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SLVTAELA 8
           SLVTAEL+
Sbjct: 129 SLVTAELS 136
>NP_060224
          Length = 1440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVTAELAP 9
           SLV +EL+P
Sbjct: 902 SLVDSELSP 910
>XP_005249256
          Length = 1054

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVTAELAP 9
           SLV +EL+P
Sbjct: 516 SLVDSELSP 524
>XP_006715189
          Length = 1240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVTAELAP 9
           SLV +EL+P
Sbjct: 902 SLVDSELSP 910
>XP_006715188
          Length = 1400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVTAELAP 9
           SLV +EL+P
Sbjct: 902 SLVDSELSP 910
>NP_683765
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SLVTAELAP 9
          SLV+A LAP
Sbjct: 89 SLVSAFLAP 97
>NP_997175
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 143 SLVPAEILP 151
>NP_997180
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 143 SLVPAEILP 151
>NP_997179
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 143 SLVPAEILP 151
>NP_997176
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 143 SLVPAEILP 151
>NP_066368
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 143 SLVPAEILP 151
>NP_005520
          Length = 4391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SLVTAELAP 9
            SL+  +LAP
Sbjct: 3770 SLIVGDLAP 3778
>NP_036516
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  LVTAELAP 9
          LVT  LAP
Sbjct: 35 LVTTNLAP 42
>NP_055887
          Length = 1281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SLVTAEL 7
            S+VTAEL
Sbjct: 1027 SMVTAEL 1033
>NP_078942
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LVTAELA 8
          LVTAE+A
Sbjct: 68 LVTAEIA 74
>XP_005260259
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  LVTAELAP 9
          LVT  LAP
Sbjct: 35 LVTTNLAP 42
>XP_006720746
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LVTAELA 8
          LVTAE+A
Sbjct: 68 LVTAEIA 74
>XP_005254721
          Length = 206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LVTAELA 8
          LVTAE+A
Sbjct: 68 LVTAEIA 74
>XP_005247534
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SLVTAELAP 9
          SLV AE+ P
Sbjct: 51 SLVPAEILP 59
>XP_005247533
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SLVTAELAP 9
          SLV AE+ P
Sbjct: 51 SLVPAEILP 59
>XP_005247532
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SLVTAELAP 9
          SLV AE+ P
Sbjct: 51 SLVPAEILP 59
>XP_005247531
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SLVTAELAP 9
          SLV AE+ P
Sbjct: 51 SLVPAEILP 59
>XP_005247530
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SLVTAELAP 9
          SLV AE+ P
Sbjct: 51 SLVPAEILP 59
>XP_005247529
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SLVTAELAP 9
          SLV AE+ P
Sbjct: 51 SLVPAEILP 59
>XP_005247528
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 143 SLVPAEILP 151
>XP_005247527
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SLVTAELAP 9
          SLV AE+ P
Sbjct: 86 SLVPAEILP 94
>XP_006713704
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SLVTAELAP 9
          SLV AE+ P
Sbjct: 87 SLVPAEILP 95
>XP_006713703
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SLVTAELAP 9
          SLV AE+ P
Sbjct: 87 SLVPAEILP 95
>XP_005247526
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SLVTAELAP 9
          SLV AE+ P
Sbjct: 87 SLVPAEILP 95
>XP_005247525
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_005247524
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_005247523
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 143 SLVPAEILP 151
>XP_005247522
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_005247521
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 143 SLVPAEILP 151
>XP_005247520
          Length = 401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_005247519
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_005247518
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_005247517
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_006713702
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_005247516
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_005247515
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_005247514
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLVTAELAP 9
           SLV AE+ P
Sbjct: 174 SLVPAEILP 182
>XP_006710661
          Length = 4057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SLVTAELAP 9
            SL+  +LAP
Sbjct: 3959 SLIVGDLAP 3967
>XP_005245920
          Length = 4392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SLVTAELAP 9
            SL+  +LAP
Sbjct: 3771 SLIVGDLAP 3779
>XP_006710660
          Length = 4397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SLVTAELAP 9
            SL+  +LAP
Sbjct: 3776 SLIVGDLAP 3784
>XP_006710659
          Length = 4556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SLVTAELAP 9
            SL+  +LAP
Sbjct: 3935 SLIVGDLAP 3943
>XP_006710658
          Length = 4563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SLVTAELAP 9
            SL+  +LAP
Sbjct: 3942 SLIVGDLAP 3950
>XP_006710657
          Length = 4579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SLVTAELAP 9
            SL+  +LAP
Sbjct: 3958 SLIVGDLAP 3966
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.119    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 319,692
Number of extensions: 423
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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