Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1935
XP_005262424                                                           18    1935
NP_997264                                                              17    3301
NP_001230925                                                           17    4312
NP_001027                                                              17    4312
NP_073619                                                              16    5631
NP_001140177                                                           16    5631
XP_006719255                                                           16    5631
XP_006719254                                                           16    5631
XP_006719253                                                           16    5631
XP_006719252                                                           16    5631
XP_006719251                                                           16    5631
XP_006719250                                                           16    5631
NP_001008219                                                           16    7355
NP_004029                                                              16    7355
NP_001008220                                                           16    7355
NP_001008222                                                           16    7355
NP_001026                                                              16    7355
NP_056190                                                              16    7355
NP_955749                                                              16    7355
NP_000690                                                              16    7355
NP_066188                                                              16    7355
XP_006711873                                                           16    7355
XP_006711872                                                           16    7355
XP_006711871                                                           16    7355
XP_006711870                                                           16    7355
XP_006711869                                                           16    7355
XP_006711868                                                           16    7355
XP_006711867                                                           16    7355
XP_006711866                                                           16    7355
XP_006711865                                                           16    7355
XP_006710644                                                           16    7355
XP_005270818                                                           16    7355
XP_006710643                                                           16    7355
XP_005270815                                                           16    7355
XP_006710642                                                           16    7355
XP_005270812                                                           16    7355
NP_060034                                                              15    9605
NP_001035026                                                           15    9605
NP_631901                                                              15    9605
NP_683684                                                              15    9605
NP_001154901                                                           15    9605
NP_036273                                                              15    9605
NP_659437                                                              15    9605
XP_005266398                                                           15    9605
XP_005266397                                                           15    9605
XP_006714518                                                           15    9605
XP_006714517                                                           15    9605
XP_006714516                                                           15    9605
XP_006714515                                                           15    9605
>NP_722576
          Length = 3080

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLTLQTRLI 9
           SLTL TRLI
Sbjct: 506 SLTLPTRLI 514
>XP_005262424
          Length = 2875

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLTLQTRLI 9
           SLTL TRLI
Sbjct: 301 SLTLPTRLI 309
>NP_997264
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TLQTRLI 9
          TLQTRLI
Sbjct: 39 TLQTRLI 45
>NP_001230925
          Length = 4865

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLTLQTRLI 9
           +L LQTRLI
Sbjct: 628 NLLLQTRLI 636
>NP_001027
          Length = 4870

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLTLQTRLI 9
           +L LQTRLI
Sbjct: 628 NLLLQTRLI 636
>NP_073619
          Length = 1183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LTLQTRL 8
            +TLQTRL
Sbjct: 1142 ITLQTRL 1148
>NP_001140177
          Length = 1570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLTLQTRLI 9
           SLT+ TRLI
Sbjct: 460 SLTVLTRLI 468
>XP_006719255
          Length = 485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTLQTRL 8
           +TLQTRL
Sbjct: 444 ITLQTRL 450
>XP_006719254
          Length = 810

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTLQTRL 8
           +TLQTRL
Sbjct: 769 ITLQTRL 775
>XP_006719253
          Length = 1031

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTLQTRL 8
           +TLQTRL
Sbjct: 990 ITLQTRL 996
>XP_006719252
          Length = 1031

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTLQTRL 8
           +TLQTRL
Sbjct: 990 ITLQTRL 996
>XP_006719251
          Length = 1116

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LTLQTRL 8
            +TLQTRL
Sbjct: 1075 ITLQTRL 1081
>XP_006719250
          Length = 1141

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LTLQTRL 8
            +TLQTRL
Sbjct: 1100 ITLQTRL 1106
>NP_001008219
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>NP_004029
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>NP_001008220
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>NP_001008222
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>NP_001026
          Length = 4967

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           L LQTRL+
Sbjct: 642 LLLQTRLV 649
>NP_056190
          Length = 929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTLQTRL 8
           LTL+TRL
Sbjct: 749 LTLETRL 755
>NP_955749
          Length = 884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTLQTRL 8
           LTL+TRL
Sbjct: 749 LTLETRL 755
>NP_000690
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>NP_066188
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>XP_006711873
          Length = 4954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           L LQTRL+
Sbjct: 642 LLLQTRLV 649
>XP_006711872
          Length = 2735

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           L LQTRL+
Sbjct: 642 LLLQTRLV 649
>XP_006711871
          Length = 4906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           L LQTRL+
Sbjct: 642 LLLQTRLV 649
>XP_006711870
          Length = 4965

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           L LQTRL+
Sbjct: 642 LLLQTRLV 649
>XP_006711869
          Length = 4973

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           L LQTRL+
Sbjct: 642 LLLQTRLV 649
>XP_006711868
          Length = 4975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           L LQTRL+
Sbjct: 642 LLLQTRLV 649
>XP_006711867
          Length = 4977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           L LQTRL+
Sbjct: 642 LLLQTRLV 649
>XP_006711866
          Length = 4984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           L LQTRL+
Sbjct: 642 LLLQTRLV 649
>XP_006711865
          Length = 4985

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           L LQTRL+
Sbjct: 642 LLLQTRLV 649
>XP_006710644
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>XP_005270818
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>XP_006710643
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>XP_005270815
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>XP_006710642
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>XP_005270812
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLTLQTRL 8
           SLTLQT L
Sbjct: 452 SLTLQTGL 459
>NP_060034
          Length = 2551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TLQTRL 8
            TLQTRL
Sbjct: 2396 TLQTRL 2401
>NP_001035026
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLQTRLI 9
           +LQTRLI
Sbjct: 827 SLQTRLI 833
>NP_631901
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           LTLQ RL+
Sbjct: 125 LTLQERLL 132
>NP_683684
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLQTRLI 9
           LTLQ RL+
Sbjct: 136 LTLQERLL 143
>NP_001154901
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLQTRLI 9
           TLQ+RLI
Sbjct: 361 TLQSRLI 367
>NP_036273
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLQTRLI 9
           +LQTRLI
Sbjct: 840 SLQTRLI 846
>NP_659437
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLQTRLI 9
           TLQ+RLI
Sbjct: 336 TLQSRLI 342
>XP_005266398
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLQTRLI 9
           +LQTRLI
Sbjct: 408 SLQTRLI 414
>XP_005266397
          Length = 709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLQTRLI 9
           +LQTRLI
Sbjct: 662 SLQTRLI 668
>XP_006714518
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLQTRLI 9
           TLQ+RLI
Sbjct: 316 TLQSRLI 322
>XP_006714517
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLQTRLI 9
           TLQ+RLI
Sbjct: 336 TLQSRLI 342
>XP_006714516
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLQTRLI 9
           TLQ+RLI
Sbjct: 341 TLQSRLI 347
>XP_006714515
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLQTRLI 9
           TLQ+RLI
Sbjct: 361 TLQSRLI 367
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.137    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 312,666
Number of extensions: 431
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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