Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060145                                                              17    2528
NP_001165447                                                           17    2528
XP_006714950                                                           17    2528
NP_001191746                                                           16    5631
NP_116217                                                              16    5631
NP_689688                                                              16    5631
NP_776173                                                              16    5631
XP_005276340                                                           16    5631
XP_006723092                                                           16    5631
XP_006719419                                                           16    5631
XP_006719416                                                           16    5631
XP_006719415                                                           16    5631
XP_006719414                                                           16    5631
XP_006719412                                                           16    5631
XP_006719411                                                           16    5631
XP_005249981                                                           16    5631
NP_001191385                                                           16    7355
NP_002800                                                              16    7355
NP_055803                                                              16    7355
NP_001276051                                                           16    7355
NP_001106189                                                           16    7355
NP_001106188                                                           16    7355
XP_006714061                                                           16    7355
XP_005248132                                                           16    7355
XP_005248131                                                           16    7355
XP_005248130                                                           16    7355
XP_005248129                                                           16    7355
XP_006714060                                                           16    7355
XP_005248128                                                           16    7355
XP_005248127                                                           16    7355
XP_005248126                                                           16    7355
XP_005248125                                                           16    7355
XP_005248120                                                           16    7355
XP_006714059                                                           16    7355
XP_005248119                                                           16    7355
XP_005248118                                                           16    7355
XP_005248117                                                           16    7355
XP_005248116                                                           16    7355
XP_005248115                                                           16    7355
XP_005248114                                                           16    7355
NP_066986                                                              16    7355
NP_001007189                                                           15    9605
NP_001229825                                                           15    9605
NP_001229826                                                           15    9605
NP_055477                                                              15    9605
NP_001129501                                                           15    9605
NP_001186408                                                           15    9605
NP_001186409                                                           15    9605
XP_005261924                                                           15    9605
XP_006724450                                                           15    9605
XP_006724449                                                           15    9605
XP_005261923                                                           15    9605
XP_006724448                                                           15    9605
XP_006724447                                                           15    9605
XP_005261922                                                           15    9605
XP_005261921                                                           15    9605
XP_005261920                                                           15    9605
XP_005261919                                                           15    9605
XP_005272299                                                           15    9605
XP_006715247                                                           15    9605
XP_006715246                                                           15    9605
XP_006715245                                                           15    9605
XP_006713783                                                           15    9605
XP_005247745                                                           15    9605
XP_006713782                                                           15    9605
NP_006290                                                              15    9605
NP_006497                                                              15    9605
>NP_060145
          Length = 1310

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLSYSRKSA 9
           SLSY+ KSA
Sbjct: 190 SLSYNNKSA 198
>NP_001165447
          Length = 1310

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLSYSRKSA 9
           SLSY+ KSA
Sbjct: 190 SLSYNNKSA 198
>XP_006714950
          Length = 1304

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLSYSRKSA 9
           SLSY+ KSA
Sbjct: 190 SLSYNNKSA 198
>NP_001191746
          Length = 574

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           SYSRKS+
Sbjct: 275 SYSRKSS 281
>NP_116217
          Length = 575

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           SYSRKS+
Sbjct: 276 SYSRKSS 282
>NP_689688
          Length = 575

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           SYSRKS+
Sbjct: 276 SYSRKSS 282
>NP_776173
          Length = 758

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           +YSRKSA
Sbjct: 676 TYSRKSA 682
>XP_005276340
          Length = 158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SYSRKSA 9
          +YSRKSA
Sbjct: 86 TYSRKSA 92
>XP_006723092
          Length = 574

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           SYSRKS+
Sbjct: 275 SYSRKSS 281
>XP_006719419
          Length = 443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           +YSRKSA
Sbjct: 361 TYSRKSA 367
>XP_006719416
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           +YSRKSA
Sbjct: 533 TYSRKSA 539
>XP_006719415
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           +YSRKSA
Sbjct: 533 TYSRKSA 539
>XP_006719414
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           +YSRKSA
Sbjct: 626 TYSRKSA 632
>XP_006719412
          Length = 724

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           +YSRKSA
Sbjct: 676 TYSRKSA 682
>XP_006719411
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           +YSRKSA
Sbjct: 656 TYSRKSA 662
>XP_005249981
          Length = 158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SYSRKSA 9
          +YSRKSA
Sbjct: 86 TYSRKSA 92
>NP_001191385
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 381 SFSRKSA 387
>NP_002800
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SLSYSRKS 8
           SLSYSR S
Sbjct: 411 SLSYSRIS 418
>NP_055803
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>NP_001276051
          Length = 1069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>NP_001106189
          Length = 1056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>NP_001106188
          Length = 1057

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_006714061
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248132
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248131
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248130
          Length = 1074

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248129
          Length = 1082

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_006714060
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248128
          Length = 1086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248127
          Length = 1322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248126
          Length = 1359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248125
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248120
          Length = 1549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_006714059
          Length = 1600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248119
          Length = 1601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248118
          Length = 1602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248117
          Length = 1626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248116
          Length = 1627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248115
          Length = 1629

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248114
          Length = 1630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSYSRK 7
           SL YSRK
Sbjct: 116 SLDYSRK 122
>NP_066986
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 381 SFSRKSA 387
>NP_001007189
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>NP_001229825
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>NP_001229826
          Length = 1503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>NP_055477
          Length = 1572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>NP_001129501
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>NP_001186408
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSYSRKS 8
           S SYSR+S
Sbjct: 395 SKSYSRRS 402
>NP_001186409
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSYSRKS 8
           S SYSR+S
Sbjct: 344 SKSYSRRS 351
>XP_005261924
          Length = 1176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>XP_006724450
          Length = 1187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>XP_006724449
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>XP_005261923
          Length = 1307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>XP_006724448
          Length = 1490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 376 SHSRKSA 382
>XP_006724447
          Length = 1516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>XP_005261922
          Length = 1525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>XP_005261921
          Length = 1581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>XP_005261920
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>XP_005261919
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYSRKSA 9
           S+SRKSA
Sbjct: 489 SHSRKSA 495
>XP_005272299
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SLSYSR 6
           SLSYSR
Sbjct: 159 SLSYSR 164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SLSYSR 6
           SLSYSR
Sbjct: 187 SLSYSR 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SLSYSR 6
           SLSYSR
Sbjct: 243 SLSYSR 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SLSYSR 6
           SLSYSR
Sbjct: 336 SLSYSR 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SLSYSR 6
           SLSYSR
Sbjct: 392 SLSYSR 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SLSYSR 6
           SLSYSR
Sbjct: 448 SLSYSR 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SLSYSR 6
           SLSYSR
Sbjct: 466 SLSYSR 471
>XP_006715247
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSYSRKS 8
           S SYSR+S
Sbjct: 395 SKSYSRRS 402
>XP_006715246
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSYSRKS 8
           S SYSR+S
Sbjct: 395 SKSYSRRS 402
>XP_006715245
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSYSRKS 8
           S SYSR+S
Sbjct: 446 SKSYSRRS 453
>XP_006713783
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SLSYSRKS 8
          S SY+RKS
Sbjct: 11 SSSYTRKS 18
>XP_005247745
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSYSRKS 8
           S SY+RKS
Sbjct: 232 SSSYTRKS 239
>XP_006713782
          Length = 854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSYSRKS 8
           S SY+RKS
Sbjct: 232 SSSYTRKS 239
>NP_006290
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSYSRKS 8
           S SYSR+S
Sbjct: 344 SKSYSRRS 351
>NP_006497
          Length = 849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSYSRKS 8
           S SY+RKS
Sbjct: 232 SSSYTRKS 239
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.102    0.230 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 447,611
Number of extensions: 457
Number of successful extensions: 73
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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