Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     869
NP_001075109                                                           19     869
NP_002449                                                              17    2528
NP_001001922                                                           17    4312
NP_055719                                                              16    5631
XP_005269686                                                           16    5631
NP_001005174                                                           16    5631
NP_940912                                                              16    7355
NP_006653                                                              15    9605
NP_064525                                                              15    9605
NP_443161                                                              15    9605
NP_056060                                                              15    9605
NP_001191008                                                           15    9605
NP_690001                                                              15    9605
NP_001191010                                                           15    9605
NP_001191009                                                           15    9605
NP_079029                                                              15    9605
NP_001190994                                                           15    9605
NP_001190996                                                           15    9605
NP_001190999                                                           15    9605
NP_001190998                                                           15    9605
NP_858056                                                              15    9605
NP_001190995                                                           15    9605
NP_001190997                                                           15    9605
NP_001008781                                                           15    9605
NP_085046                                                              15    9605
NP_001001851                                                           15    9605
XP_005269089                                                           15    9605
XP_006719577                                                           15    9605
XP_006719576                                                           15    9605
XP_006719575                                                           15    9605
XP_006719574                                                           15    9605
XP_006719573                                                           15    9605
XP_005269086                                                           15    9605
XP_006719572                                                           15    9605
XP_006719571                                                           15    9605
XP_005269085                                                           15    9605
XP_006719570                                                           15    9605
XP_006719569                                                           15    9605
XP_006719568                                                           15    9605
XP_006719567                                                           15    9605
XP_006718827                                                           15    9605
XP_006715101                                                           15    9605
XP_006715100                                                           15    9605
XP_005249021                                                           15    9605
XP_006715099                                                           15    9605
XP_006715098                                                           15    9605
XP_006715097                                                           15    9605
XP_006715096                                                           15    9605
XP_006712824                                                           15    9605
XP_006710380                                                           15    9605
XP_005245788                                                           15    9605
XP_006710379                                                           15    9605
XP_006710378                                                           15    9605
NP_001001913                                                           15    9605
>NP_008835
          Length = 4128

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLSYELILQ 9
           S SYELILQ
Sbjct: 648 SFSYELILQ 656
>NP_001075109
          Length = 4097

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLSYELILQ 9
           S SYELILQ
Sbjct: 648 SFSYELILQ 656
>NP_002449
          Length = 5762

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SYELILQ 9
           SYELILQ
Sbjct: 961 SYELILQ 967
>NP_001001922
          Length = 324

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLSYELILQ 9
           SLSY LIL+
Sbjct: 224 SLSYTLILK 232
>NP_055719
          Length = 512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLSYELILQ 9
           SL+YE +LQ
Sbjct: 450 SLTYEEVLQ 458
>XP_005269686
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLSYELILQ 9
           SL+YE +LQ
Sbjct: 470 SLTYEEVLQ 478
>NP_001005174
          Length = 321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLSYELILQ 9
           S+SY +ILQ
Sbjct: 217 SVSYTMILQ 225
>NP_940912
          Length = 1313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLSYELILQ 9
           SL+YE +LQ
Sbjct: 145 SLAYEELLQ 153
>NP_006653
          Length = 3230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYELILQ 9
           SY+L+LQ
Sbjct: 724 SYKLVLQ 730
>NP_064525
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 335 NLAYEIIL 342
>NP_443161
          Length = 1412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  LSYELILQ 9
          L+YEL+++
Sbjct: 89 LTYELVIE 96
>NP_056060
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1045 NLTYEIIL 1052
>NP_001191008
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 200 NLAYEIIL 207
>NP_690001
          Length = 1248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1169 NLAYEIIL 1176
>NP_001191010
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 175 NLAYEIIL 182
>NP_001191009
          Length = 266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 175 NLAYEIIL 182
>NP_079029
          Length = 1316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LSYELILQ 9
           L Y++ILQ
Sbjct: 330 LGYQMILQ 337
>NP_001190994
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 199 NLAYEIIL 206
>NP_001190996
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 304 NLAYEIIL 311
>NP_001190999
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 335 NLAYEIIL 342
>NP_001190998
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 359 NLAYEIIL 366
>NP_858056
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 419 NLAYEIIL 426
>NP_001190995
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 267 NLAYEIIL 274
>NP_001190997
          Length = 460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 395 NLAYEIIL 402
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SYELILQ 9
            SY+LI+Q
Sbjct: 1736 SYQLIIQ 1742
>NP_085046
          Length = 942

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSYELILQ 9
           LSYE +LQ
Sbjct: 157 LSYEELLQ 164
>NP_001001851
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSYELILQ 9
           LSYE +LQ
Sbjct: 157 LSYEELLQ 164
>XP_005269089
          Length = 266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLSYELIL 8
           +L+YE+IL
Sbjct: 175 NLAYEIIL 182
>XP_006719577
          Length = 1184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1105 NLAYEIIL 1112
>XP_006719576
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1109 NLAYEIIL 1116
>XP_006719575
          Length = 1200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1109 NLAYEIIL 1116
>XP_006719574
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1133 NLAYEIIL 1140
>XP_006719573
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1169 NLAYEIIL 1176
>XP_005269086
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1165 NLAYEIIL 1172
>XP_006719572
          Length = 1259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1169 NLAYEIIL 1176
>XP_006719571
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1194 NLAYEIIL 1201
>XP_005269085
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1169 NLAYEIIL 1176
>XP_006719570
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1194 NLAYEIIL 1201
>XP_006719569
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1193 NLAYEIIL 1200
>XP_006719568
          Length = 1284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1194 NLAYEIIL 1201
>XP_006719567
          Length = 1284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1193 NLAYEIIL 1200
>XP_006718827
          Length = 3479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYELILQ 9
           SY+LI+Q
Sbjct: 626 SYQLIIQ 632
>XP_006715101
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1045 NLTYEIIL 1052
>XP_006715100
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1046 NLTYEIIL 1053
>XP_005249021
          Length = 1155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1066 NLTYEIIL 1073
>XP_006715099
          Length = 1156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1067 NLTYEIIL 1074
>XP_006715098
          Length = 1161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1066 NLTYEIIL 1073
>XP_006715097
          Length = 1171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1066 NLTYEIIL 1073
>XP_006715096
          Length = 1172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLSYELIL 8
            +L+YE+IL
Sbjct: 1067 NLTYEIIL 1074
>XP_006712824
          Length = 1056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LSYELILQ 9
           L Y++ILQ
Sbjct: 330 LGYQMILQ 337
>XP_006710380
          Length = 1398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  LSYELILQ 9
          L+YEL+++
Sbjct: 89 LTYELVIE 96
>XP_005245788
          Length = 1434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  LSYELILQ 9
          L+YEL+++
Sbjct: 89 LTYELVIE 96
>XP_006710379
          Length = 1452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  LSYELILQ 9
          L+YEL+++
Sbjct: 89 LTYELVIE 96
>XP_006710378
          Length = 1478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  LSYELILQ 9
          L+YEL+++
Sbjct: 89 LTYELVIE 96
>NP_001001913
          Length = 320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLSYELILQ 9
           ++SY +ILQ
Sbjct: 217 TISYTMILQ 225
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.136    0.323 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 506,123
Number of extensions: 914
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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