Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     665
XP_005262424                                                           19     665
NP_663623                                                              16    5631
NP_001026850                                                           16    5631
NP_004341                                                              16    5631
NP_078966                                                              16    5631
NP_001013725                                                           16    5631
NP_056386                                                              16    5631
NP_001010854                                                           16    5631
XP_005255038                                                           16    5631
XP_005255037                                                           16    5631
XP_005254450                                                           16    5631
XP_005254449                                                           16    5631
XP_005267424                                                           16    5631
XP_006720122                                                           16    5631
XP_006720121                                                           16    5631
XP_006716738                                                           16    5631
XP_006716737                                                           16    5631
XP_005272407                                                           16    5631
XP_006716177                                                           16    5631
XP_006715520                                                           16    5631
XP_005246081                                                           16    5631
NP_001093879                                                           16    5631
NP_116291                                                              16    5631
NP_060726                                                              16    7355
NP_001138624                                                           16    7355
NP_689628                                                              16    7355
NP_620063                                                              16    7355
NP_055917                                                              16    7355
NP_079079                                                              16    7355
NP_001165335                                                           16    7355
XP_005273458                                                           16    7355
XP_005273457                                                           16    7355
XP_006716349                                                           16    7355
XP_006710633                                                           16    7355
XP_006710632                                                           16    7355
XP_006710631                                                           16    7355
XP_006710630                                                           16    7355
XP_006710629                                                           16    7355
XP_006710628                                                           16    7355
XP_006710627                                                           16    7355
XP_006710626                                                           16    7355
NP_001839                                                              15    9605
NP_003310                                                              15    9605
NP_000183                                                              15    9605
NP_001136233                                                           15    9605
NP_852259                                                              15    9605
NP_597676                                                              15    9605
NP_542448                                                              15    9605
NP_001243779                                                           15    9605
NP_596869                                                              15    9605
NP_150628                                                              15    9605
XP_006724027                                                           15    9605
XP_005254813                                                           15    9605
XP_005246888                                                           15    9605
XP_006712788                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
NP_543146                                                              15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605
>NP_722576
          Length = 3080

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLSTTDHTL 9
            S STTDHTL
Sbjct: 2132 SPSTTDHTL 2140
>XP_005262424
          Length = 2875

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLSTTDHTL 9
            S STTDHTL
Sbjct: 1927 SPSTTDHTL 1935
>NP_663623
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLSTTDHTL 9
           +++TT HTL
Sbjct: 356 NITTTPHTL 364
>NP_001026850
          Length = 429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSTTDH 7
           SLSTT H
Sbjct: 232 SLSTTSH 238
>NP_004341
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSTTDH 7
           SLSTT H
Sbjct: 218 SLSTTSH 224
>NP_078966
          Length = 14507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    SLSTTDH 7
            SLSTT H
Sbjct: 7745 SLSTTSH 7751
>NP_001013725
          Length = 1649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SLSTTDHT 8
           SLS  DHT
Sbjct: 205 SLSNQDHT 212
>NP_056386
          Length = 1112

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSTTDHT 8
           SLS+T HT
Sbjct: 898 SLSSTHHT 905
>NP_001010854
          Length = 843

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSTTDH 7
           SLS TDH
Sbjct: 509 SLSPTDH 515
>XP_005255038
          Length = 321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  STTDHTL 9
          +T+DHTL
Sbjct: 18 TTSDHTL 24
>XP_005255037
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  STTDHTL 9
          +T+DHTL
Sbjct: 18 TTSDHTL 24
>XP_005254450
          Length = 1505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SLSTTDHT 8
           SLS  DHT
Sbjct: 205 SLSNQDHT 212
>XP_005254449
          Length = 1626

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SLSTTDHT 8
           SLS  DHT
Sbjct: 205 SLSNQDHT 212
>XP_005267424
          Length = 656

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSTTDH 7
           SLS TDH
Sbjct: 251 SLSPTDH 257
>XP_006720122
          Length = 820

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSTTDH 7
           SLS TDH
Sbjct: 415 SLSPTDH 421
>XP_006720121
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSTTDH 7
           SLS TDH
Sbjct: 517 SLSPTDH 523
>XP_006716738
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   STTDHTL 9
           STT HTL
Sbjct: 441 STTPHTL 447
>XP_006716737
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   STTDHTL 9
           STT HTL
Sbjct: 441 STTPHTL 447
>XP_005272407
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   STTDHTL 9
           STT HTL
Sbjct: 441 STTPHTL 447
>XP_006716177
          Length = 386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSTTDHT 8
           S STT+HT
Sbjct: 222 SPSTTEHT 229
>XP_006715520
          Length = 1056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSTTDHT 8
           SLS+T HT
Sbjct: 842 SLSSTHHT 849
>XP_005246081
          Length = 429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLSTTDH 7
           SLSTT H
Sbjct: 232 SLSTTSH 238
>NP_001093879
          Length = 1105

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLSTTDHT 8
           SLS+T HT
Sbjct: 891 SLSSTHHT 898
>NP_116291
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   STTDHTL 9
           STT HTL
Sbjct: 441 STTPHTL 447
>NP_060726
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SLSTTDHT 8
           SLS T HT
Sbjct: 335 SLSLTSHT 342
>NP_001138624
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SLSTTDHT 8
           S STT HT
Sbjct: 155 SSSTTSHT 162
>NP_689628
          Length = 397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SLSTTDHT 8
           S STT HT
Sbjct: 180 SSSTTSHT 187
>NP_620063
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  SLSTTDH 7
          SLSTT H
Sbjct: 56 SLSTTHH 62
>NP_055917
          Length = 1426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TTDHTL 9
           TT+HTL
Sbjct: 976 TTEHTL 981
>NP_079079
          Length = 446

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   STTDHT 8
           STT+HT
Sbjct: 200 STTEHT 205
>NP_001165335
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   STTDHT 8
           STT+HT
Sbjct: 160 STTEHT 165
>XP_005273458
          Length = 307

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  SLSTTDHT 8
          S STT HT
Sbjct: 90 SSSTTSHT 97
>XP_005273457
          Length = 307

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  SLSTTDHT 8
          S STT HT
Sbjct: 90 SSSTTSHT 97
>XP_006716349
          Length = 391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SLSTTDHT 8
           S STT HT
Sbjct: 180 SSSTTSHT 187
>XP_006710633
          Length = 1250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TTDHTL 9
           TT+HTL
Sbjct: 800 TTEHTL 805
>XP_006710632
          Length = 1389

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TTDHTL 9
           TT+HTL
Sbjct: 939 TTEHTL 944
>XP_006710631
          Length = 1412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TTDHTL 9
           TT+HTL
Sbjct: 962 TTEHTL 967
>XP_006710630
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TTDHTL 9
           TT+HTL
Sbjct: 974 TTEHTL 979
>XP_006710629
          Length = 1425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TTDHTL 9
           TT+HTL
Sbjct: 975 TTEHTL 980
>XP_006710628
          Length = 1426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TTDHTL 9
           TT+HTL
Sbjct: 976 TTEHTL 981
>XP_006710627
          Length = 1426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TTDHTL 9
           TT+HTL
Sbjct: 976 TTEHTL 981
>XP_006710626
          Length = 1426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TTDHTL 9
           TT+HTL
Sbjct: 976 TTEHTL 981
>NP_001839
          Length = 1028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SLSTTDHT 8
           S+  TDHT
Sbjct: 201 SIIATDHT 208
>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2     LSTTDHTL 9
             +ST +HTL
Sbjct: 19342 ISTDNHTL 19349
>NP_000183
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   STTDH 7
           STTDH
Sbjct: 332 STTDH 336
>NP_001136233
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   STTDH 7
           STTDH
Sbjct: 241 STTDH 245
>NP_852259
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   STTDH 7
           STTDH
Sbjct: 332 STTDH 336
>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2     LSTTDHTL 9
             +ST +HTL
Sbjct: 19467 ISTDNHTL 19474
>NP_542448
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   STTDH 7
           STTDH
Sbjct: 282 STTDH 286
>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2     LSTTDHTL 9
             +ST +HTL
Sbjct: 26766 ISTDNHTL 26773
>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2     LSTTDHTL 9
             +ST +HTL
Sbjct: 25839 ISTDNHTL 25846
>NP_150628
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   STTDH 7
           STTDH
Sbjct: 241 STTDH 245
>XP_006724027
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   SLSTTDHT 8
           S+  TDHT
Sbjct: 201 SIIATDHT 208
>XP_005254813
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3  STTDH 7
          STTDH
Sbjct: 94 STTDH 98
>XP_005246888
          Length = 22663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2     LSTTDHTL 9
             +ST +HTL
Sbjct: 15079 ISTDNHTL 15086
>XP_006712788
          Length = 24022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2     LSTTDHTL 9
             +ST +HTL
Sbjct: 16438 ISTDNHTL 16445
>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2     LSTTDHTL 9
             +ST +HTL
Sbjct: 26394 ISTDNHTL 26401
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2     LSTTDHTL 9
             +ST +HTL
Sbjct: 27900 ISTDNHTL 27907
>NP_543146
          Length = 1393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  LSTTDH 7
          LST+DH
Sbjct: 41 LSTSDH 46
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2     LSTTDHTL 9
             +ST +HTL
Sbjct: 28407 ISTDNHTL 28414
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2     LSTTDHTL 9
             +ST +HTL
Sbjct: 19534 ISTDNHTL 19541
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.111    0.290 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 573,126
Number of extensions: 659
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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