Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              17    3301
XP_005269721                                                           17    3301
NP_056385                                                              17    4312
NP_001120703                                                           17    4312
NP_001277155                                                           16    7355
NP_001277156                                                           16    7355
NP_055998                                                              16    7355
NP_001158136                                                           16    7355
XP_006714675                                                           16    7355
XP_006714673                                                           16    7355
XP_006714672                                                           16    7355
XP_006714670                                                           16    7355
XP_006714669                                                           16    7355
XP_006714668                                                           16    7355
XP_006714667                                                           16    7355
XP_006714666                                                           16    7355
XP_005248555                                                           16    7355
XP_006714665                                                           16    7355
NP_001275661                                                           15    9605
NP_060939                                                              15    9605
NP_060102                                                              15    9605
NP_001275662                                                           15    9605
XP_005257564                                                           15    9605
>NP_036462
          Length = 2073

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLSSQKSST 9
           S SSQKSST
Sbjct: 504 SPSSQKSST 512
>XP_005269721
          Length = 2073

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLSSQKSST 9
           S SSQKSST
Sbjct: 504 SPSSQKSST 512
>NP_056385
          Length = 1259

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLSSQKSST 9
           SLSS +SST
Sbjct: 403 SLSSSRSST 411
>NP_001120703
          Length = 1235

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLSSQKSST 9
           SLSS +SST
Sbjct: 403 SLSSSRSST 411
>NP_001277155
          Length = 2417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2005 SLSSQKPS 2012
>NP_001277156
          Length = 2362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 1950 SLSSQKPS 1957
>NP_055998
          Length = 2434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2022 SLSSQKPS 2029
>NP_001158136
          Length = 2623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2211 SLSSQKPS 2218
>XP_006714675
          Length = 2275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 1863 SLSSQKPS 1870
>XP_006714673
          Length = 2362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 1950 SLSSQKPS 1957
>XP_006714672
          Length = 2414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2002 SLSSQKPS 2009
>XP_006714670
          Length = 2425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2013 SLSSQKPS 2020
>XP_006714669
          Length = 2429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2017 SLSSQKPS 2024
>XP_006714668
          Length = 2429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2017 SLSSQKPS 2024
>XP_006714667
          Length = 2432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2020 SLSSQKPS 2027
>XP_006714666
          Length = 2432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2020 SLSSQKPS 2027
>XP_005248555
          Length = 2626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2214 SLSSQKPS 2221
>XP_006714665
          Length = 2651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SLSSQKSS 8
            SLSSQK S
Sbjct: 2239 SLSSQKPS 2246
>NP_001275661
          Length = 1127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLSSQKSST 9
           SLS QK+S+
Sbjct: 152 SLSEQKTSS 160
>NP_060939
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLSSQKSST 9
           SLS QK+S+
Sbjct: 152 SLSEQKTSS 160
>NP_060102
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSSQKSST 9
           +SSQ SST
Sbjct: 196 ISSQNSST 203
>NP_001275662
          Length = 1127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLSSQKSST 9
           SLS QK+S+
Sbjct: 152 SLSEQKTSS 160
>XP_005257564
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLSSQKSST 9
           SLS QK+S+
Sbjct: 152 SLSEQKTSS 160
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.260   0.0769    0.147 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 256,306
Number of extensions: 295
Number of successful extensions: 23
Number of sequences better than 10000.0: 23
Number of HSP's gapped: 23
Number of HSP's successfully gapped: 23
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 19 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.2 bits)
S2: 28 (15.4 bits)

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