Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_065810                                                              18    1482
XP_006720684                                                           18    1482
NP_061836                                                              17    4312
NP_387505                                                              17    4312
XP_005261051                                                           17    4312
XP_006711599                                                           17    4312
XP_005245543                                                           17    4312
XP_006711598                                                           17    4312
XP_006711597                                                           17    4312
XP_006711596                                                           17    4312
XP_006711595                                                           17    4312
XP_006711594                                                           17    4312
NP_110391                                                              17    4312
NP_076968                                                              16    5631
XP_005254714                                                           16    5631
NP_001098677                                                           16    7355
NP_002281                                                              16    7355
NP_001098676                                                           16    7355
NP_055665                                                              16    7355
NP_001028289                                                           16    7355
NP_065772                                                              16    7355
XP_006724837                                                           16    7355
XP_006715544                                                           16    7355
XP_005267041                                                           16    7355
XP_006715543                                                           16    7355
XP_005267040                                                           16    7355
XP_006713496                                                           16    7355
XP_005265679                                                           16    7355
NP_878918                                                              15    9605
NP_055995                                                              15    9605
NP_115804                                                              15    9605
NP_077307                                                              15    9605
NP_001034288                                                           15    9605
NP_001248768                                                           15    9605
NP_006176                                                              15    9605
NP_001273490                                                           15    9605
XP_006724772                                                           15    9605
XP_005260606                                                           15    9605
XP_006720147                                                           15    9605
XP_005267517                                                           15    9605
XP_005267516                                                           15    9605
XP_005267515                                                           15    9605
XP_005267514                                                           15    9605
XP_005267513                                                           15    9605
XP_005267512                                                           15    9605
XP_005267511                                                           15    9605
XP_006718633                                                           15    9605
XP_006718632                                                           15    9605
XP_006718631                                                           15    9605
XP_006718630                                                           15    9605
XP_006718629                                                           15    9605
XP_006718628                                                           15    9605
XP_006718627                                                           15    9605
XP_006718626                                                           15    9605
XP_006718625                                                           15    9605
XP_006710654                                                           15    9605
>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SLSEQADSL 9
            SLSE+ADSL
Sbjct: 2376 SLSEEADSL 2384
>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SLSEQADSL 9
            SLSE+ADSL
Sbjct: 2368 SLSEEADSL 2376
>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SLSEQADSL 9
            SLSE+ADSL
Sbjct: 2329 SLSEEADSL 2337
>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SLSEQADSL 9
            SLSE+ADSL
Sbjct: 2408 SLSEEADSL 2416
>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SLSEQADSL 9
            SLSE+ADSL
Sbjct: 2421 SLSEEADSL 2429
>NP_065810
          Length = 4700

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            S SEQADSL
Sbjct: 1313 SYSEQADSL 1321
>XP_006720684
          Length = 4713

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            S SEQADSL
Sbjct: 1326 SYSEQADSL 1334
>NP_061836
          Length = 2320

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLSEQADS 8
            S+SE+ADS
Sbjct: 1786 SISEEADS 1793
>NP_387505
          Length = 2269

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLSEQADS 8
            S+SE+ADS
Sbjct: 1786 SISEEADS 1793
>XP_005261051
          Length = 2242

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLSEQADS 8
            S+SE+ADS
Sbjct: 1708 SISEEADS 1715
>XP_006711599
          Length = 185

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  SLSEQADSL 9
          +++EQADSL
Sbjct: 12 AVTEQADSL 20
>XP_005245543
          Length = 202

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  SLSEQADSL 9
          +++EQADSL
Sbjct: 12 AVTEQADSL 20
>XP_006711598
          Length = 313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  SLSEQADSL 9
          +++EQADSL
Sbjct: 12 AVTEQADSL 20
>XP_006711597
          Length = 319

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  SLSEQADSL 9
          +++EQADSL
Sbjct: 12 AVTEQADSL 20
>XP_006711596
          Length = 413

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  SLSEQADSL 9
          +++EQADSL
Sbjct: 12 AVTEQADSL 20
>XP_006711595
          Length = 415

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  SLSEQADSL 9
          +++EQADSL
Sbjct: 12 AVTEQADSL 20
>XP_006711594
          Length = 442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  SLSEQADSL 9
          +++EQADSL
Sbjct: 12 AVTEQADSL 20
>NP_110391
          Length = 508

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  SLSEQADSL 9
          +++EQADSL
Sbjct: 12 AVTEQADSL 20
>NP_076968
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSEQADSL 9
           LSE ADSL
Sbjct: 205 LSEAADSL 212
>XP_005254714
          Length = 448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSEQADSL 9
           LSE ADSL
Sbjct: 205 LSEAADSL 212
>NP_001098677
          Length = 1816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLSEQADSL 9
           SLS  ADSL
Sbjct: 526 SLSTSADSL 534
>NP_002281
          Length = 1816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLSEQADSL 9
           SLS  ADSL
Sbjct: 526 SLSTSADSL 534
>NP_001098676
          Length = 1823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLSEQADSL 9
           SLS  ADSL
Sbjct: 533 SLSTSADSL 541
>NP_055665
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLSEQADS 8
           SLS++ADS
Sbjct: 810 SLSQKADS 817
>NP_001028289
          Length = 1075

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLSEQADS 8
           SLS++ADS
Sbjct: 786 SLSQKADS 793
>NP_065772
          Length = 1709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLSEQADSL 9
           SLSE +DSL
Sbjct: 144 SLSEISDSL 152
>XP_006724837
          Length = 1533

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SLSEQADSL 9
          SLSE +DSL
Sbjct: 4  SLSEISDSL 12
>XP_006715544
          Length = 1810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLSEQADSL 9
           SLS  ADSL
Sbjct: 520 SLSTSADSL 528
>XP_005267041
          Length = 1823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLSEQADSL 9
           SLS  ADSL
Sbjct: 533 SLSTSADSL 541
>XP_006715543
          Length = 1823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLSEQADSL 9
           SLS  ADSL
Sbjct: 533 SLSTSADSL 541
>XP_005267040
          Length = 1823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLSEQADSL 9
           SLS  ADSL
Sbjct: 533 SLSTSADSL 541
>XP_006713496
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLSEQADS 8
           SLS++ADS
Sbjct: 302 SLSQKADS 309
>XP_005265679
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLSEQADS 8
           SLS++ADS
Sbjct: 810 SLSQKADS 817
>NP_878918
          Length = 6907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            +L E+ADS+
Sbjct: 2954 ALQEEADSI 2962
>NP_055995
          Length = 6885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            +L E+ADS+
Sbjct: 2954 ALQEEADSI 2962
>NP_115804
          Length = 1810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LSEQADSL 9
            LS+Q DSL
Sbjct: 1080 LSQQEDSL 1087
>NP_077307
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 LSEQADSL 9
         +SE++DSL
Sbjct: 1 MSEESDSL 8
>NP_001034288
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 LSEQADSL 9
         +SE++DSL
Sbjct: 1 MSEESDSL 8
>NP_001248768
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 LSEQADSL 9
         +SE++DSL
Sbjct: 1 MSEESDSL 8
>NP_006176
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>NP_001273490
          Length = 2101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>XP_006724772
          Length = 1605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSEQADSL 9
           LS+Q DSL
Sbjct: 875 LSQQEDSL 882
>XP_005260606
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 LSEQADSL 9
         +SE++DSL
Sbjct: 1 MSEESDSL 8
>XP_006720147
          Length = 4788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            +L E+ADS+
Sbjct: 2954 ALQEEADSI 2962
>XP_005267517
          Length = 6883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            +L E+ADS+
Sbjct: 2954 ALQEEADSI 2962
>XP_005267516
          Length = 6884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            +L E+ADS+
Sbjct: 2954 ALQEEADSI 2962
>XP_005267515
          Length = 6899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            +L E+ADS+
Sbjct: 2954 ALQEEADSI 2962
>XP_005267514
          Length = 6908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            +L E+ADS+
Sbjct: 2954 ALQEEADSI 2962
>XP_005267513
          Length = 6921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            +L E+ADS+
Sbjct: 2954 ALQEEADSI 2962
>XP_005267512
          Length = 6922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            +L E+ADS+
Sbjct: 2954 ALQEEADSI 2962
>XP_005267511
          Length = 6922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SLSEQADSL 9
            +L E+ADS+
Sbjct: 2954 ALQEEADSI 2962
>XP_006718633
          Length = 2101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>XP_006718632
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>XP_006718631
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>XP_006718630
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>XP_006718629
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>XP_006718628
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>XP_006718627
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>XP_006718626
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>XP_006718625
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    EQADSL 9
            EQADSL
Sbjct: 1141 EQADSL 1146
>XP_006710654
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SEQADS 8
           SEQADS
Sbjct: 346 SEQADS 351
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.286    0.104    0.223 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 410,610
Number of extensions: 743
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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