Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_689799                                                              18    1482
XP_006717717                                                           18    1482
XP_005269639                                                           18    1482
XP_006717716                                                           18    1482
XP_006717715                                                           18    1482
XP_006717714                                                           18    1482
XP_006717713                                                           18    1482
XP_006717712                                                           18    1482
XP_006717711                                                           18    1482
XP_005269635                                                           18    1482
XP_006717710                                                           18    1482
XP_006717709                                                           18    1482
XP_006717708                                                           18    1482
NP_061923                                                              17    2528
XP_006723678                                                           17    2528
XP_005263134                                                           17    2528
XP_006714303                                                           17    2528
XP_005263133                                                           17    2528
XP_005263132                                                           17    2528
XP_005263131                                                           17    2528
XP_005263130                                                           17    2528
NP_003236                                                              17    2528
NP_001018048                                                           17    4312
NP_056001                                                              17    4312
NP_001018047                                                           17    4312
NP_150648                                                              17    4312
NP_002942                                                              16    5631
XP_006723915                                                           16    5631
XP_006723914                                                           16    5631
XP_005260548                                                           16    5631
XP_006723913                                                           16    5631
XP_006723912                                                           16    5631
XP_005246473                                                           16    5631
XP_005246468                                                           16    5631
XP_005246467                                                           16    5631
XP_005246465                                                           16    5631
XP_005246464                                                           16    5631
XP_005246461                                                           16    5631
XP_005246460                                                           16    5631
XP_005246458                                                           16    5631
XP_005246456                                                           16    5631
XP_005246455                                                           16    5631
XP_005246454                                                           16    5631
NP_060170                                                              16    7355
NP_001229658                                                           16    7355
NP_055864                                                              16    7355
XP_006722363                                                           16    7355
NP_001020471                                                           16    7355
NP_001238965                                                           15    9605
NP_001238966                                                           15    9605
NP_002859                                                              15    9605
NP_001128411                                                           15    9605
NP_001004751                                                           15    9605
NP_996759                                                              15    9605
NP_004785                                                              15    9605
NP_073606                                                              15    9605
NP_001036039                                                           15    9605
XP_005255025                                                           15    9605
XP_005269108                                                           15    9605
XP_005269109                                                           15    9605
XP_006719603                                                           15    9605
NP_004052                                                              15    9605
NP_057262                                                              15    9605
NP_002700                                                              15    9605
>NP_689799
          Length = 1684

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 582 SLNIDSIF 589
>XP_006717717
          Length = 859

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 604 SLNIDSIF 611
>XP_005269639
          Length = 1580

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 525 SLNIDSIF 532
>XP_006717716
          Length = 1619

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 604 SLNIDSIF 611
>XP_006717715
          Length = 1660

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 547 SLNIDSIF 554
>XP_006717714
          Length = 1665

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 604 SLNIDSIF 611
>XP_006717713
          Length = 1666

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 604 SLNIDSIF 611
>XP_006717712
          Length = 1670

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 604 SLNIDSIF 611
>XP_006717711
          Length = 1677

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 604 SLNIDSIF 611
>XP_005269635
          Length = 1695

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 582 SLNIDSIF 589
>XP_006717710
          Length = 1706

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 604 SLNIDSIF 611
>XP_006717709
          Length = 1712

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 604 SLNIDSIF 611
>XP_006717708
          Length = 1717

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           SLN+DS+F
Sbjct: 604 SLNIDSIF 611
>NP_061923
          Length = 1073

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           +LNVDS+F
Sbjct: 590 TLNVDSIF 597
>XP_006723678
          Length = 718

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LNVDSLFL 9
           LNVDS+F+
Sbjct: 164 LNVDSVFM 171
>XP_005263134
          Length = 800

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           +LNVDS+F
Sbjct: 590 TLNVDSIF 597
>XP_006714303
          Length = 957

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           +LNVDS+F
Sbjct: 474 TLNVDSIF 481
>XP_005263133
          Length = 1022

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           +LNVDS+F
Sbjct: 539 TLNVDSIF 546
>XP_005263132
          Length = 1023

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           +LNVDS+F
Sbjct: 540 TLNVDSIF 547
>XP_005263131
          Length = 1073

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           +LNVDS+F
Sbjct: 590 TLNVDSIF 597
>XP_005263130
          Length = 1073

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLNVDSLF 8
           +LNVDS+F
Sbjct: 590 TLNVDSIF 597
>NP_003236
          Length = 693

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LNVDSLFL 9
           LNVDS+F+
Sbjct: 139 LNVDSVFM 146
>NP_001018048
          Length = 3069

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    LNVDSLFL 9
            +N+DS+F+
Sbjct: 1724 MNIDSIFI 1731
>NP_056001
          Length = 3095

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    LNVDSLFL 9
            +N+DS+F+
Sbjct: 1724 MNIDSIFI 1731
>NP_001018047
          Length = 3135

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    LNVDSLFL 9
            +N+DS+F+
Sbjct: 1685 MNIDSIFI 1692
>NP_150648
          Length = 3174

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    LNVDSLFL 9
            +N+DS+F+
Sbjct: 1724 MNIDSIFI 1731
>NP_002942
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  NVDSLF 8
          NVDSLF
Sbjct: 83 NVDSLF 88
>XP_006723915
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  NVDSLF 8
          NVDSLF
Sbjct: 83 NVDSLF 88
>XP_006723914
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  NVDSLF 8
          NVDSLF
Sbjct: 83 NVDSLF 88
>XP_005260548
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  NVDSLF 8
          NVDSLF
Sbjct: 83 NVDSLF 88
>XP_006723913
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  NVDSLF 8
          NVDSLF
Sbjct: 83 NVDSLF 88
>XP_006723912
          Length = 663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  NVDSLF 8
          NVDSLF
Sbjct: 83 NVDSLF 88
>XP_005246473
          Length = 2246

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2227 SLILDSLFL 2235
>XP_005246468
          Length = 2273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2254 SLILDSLFL 2262
>XP_005246467
          Length = 2337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2318 SLILDSLFL 2326
>XP_005246465
          Length = 2362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2343 SLILDSLFL 2351
>XP_005246464
          Length = 2363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2344 SLILDSLFL 2352
>XP_005246461
          Length = 2392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2373 SLILDSLFL 2381
>XP_005246460
          Length = 2393

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2374 SLILDSLFL 2382
>XP_005246458
          Length = 2427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2408 SLILDSLFL 2416
>XP_005246456
          Length = 2452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2433 SLILDSLFL 2441
>XP_005246455
          Length = 2458

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2439 SLILDSLFL 2447
>XP_005246454
          Length = 2483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SLNVDSLFL 9
            SL +DSLFL
Sbjct: 2464 SLILDSLFL 2472
>NP_060170
          Length = 219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LNVDSLF 8
           L+VDSLF
Sbjct: 132 LDVDSLF 138
>NP_001229658
          Length = 777

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LNVDSLF 8
           L+VDSLF
Sbjct: 132 LDVDSLF 138
>NP_055864
          Length = 914

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LNVDSLFL 9
          L VD+LFL
Sbjct: 56 LKVDTLFL 63
>XP_006722363
          Length = 212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLNVDSLFL 9
           + NVD +FL
Sbjct: 158 NFNVDEIFL 166
>NP_001020471
          Length = 244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLNVDSLFL 9
           + NVD +FL
Sbjct: 190 NFNVDEIFL 198
>NP_001238965
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNVDSLFL 9
           ++NV+ LFL
Sbjct: 167 AMNVNDLFL 175
>NP_001238966
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNVDSLFL 9
           ++NV+ LFL
Sbjct: 126 AMNVNDLFL 134
>NP_002859
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNVDSLFL 9
           ++NV+ LFL
Sbjct: 167 AMNVNDLFL 175
>NP_001128411
          Length = 190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NVDSLFL 9
           NVDS+F+
Sbjct: 128 NVDSVFV 134
>NP_001004751
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNVDSLFL 9
           + VDSLF+
Sbjct: 220 MGVDSLFI 227
>NP_996759
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  LNVDSL 7
          LNVDSL
Sbjct: 6  LNVDSL 11
>NP_004785
          Length = 237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNVDSLFL 9
           S NV+S+F+
Sbjct: 188 SQNVESIFM 196
>NP_073606
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLNVDSLF 8
           SLNVD+ F
Sbjct: 572 SLNVDTPF 579
>NP_001036039
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLNVDSLF 8
           SLNVD+ F
Sbjct: 571 SLNVDTPF 578
>XP_005255025
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLNVDSLF 8
           SLNVD+ F
Sbjct: 571 SLNVDTPF 578
>XP_005269108
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNVDSLFL 9
           ++NV+ LFL
Sbjct: 167 AMNVNDLFL 175
>XP_005269109
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNVDSLFL 9
           ++NV+ LFL
Sbjct: 167 AMNVNDLFL 175
>XP_006719603
          Length = 250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNVDSLFL 9
           ++NV+ LFL
Sbjct: 202 AMNVNDLFL 210
>NP_004052
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNVDSLFL 9
           S NV+++FL
Sbjct: 600 SCNVEAIFL 608
>NP_057262
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NVDSLFL 9
           NVDS+F+
Sbjct: 173 NVDSVFV 179
>NP_002700
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  LNVDSL 7
          LNVDSL
Sbjct: 6  LNVDSL 11
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.142    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 446,296
Number of extensions: 725
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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