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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001120972                                                           19     665
XP_006716051                                                           19     665
NP_077026                                                              16    5631
NP_115897                                                              16    5631
NP_001269231                                                           16    5631
NP_001167563                                                           16    5631
XP_006724915                                                           16    5631
XP_006724914                                                           16    5631
XP_006724913                                                           16    5631
NP_055137                                                              16    7355
NP_060141                                                              16    7355
NP_008849                                                              16    7355
NP_001020127                                                           16    7355
NP_001013425                                                           15    9605
NP_068781                                                              15    9605
NP_001153218                                                           15    9605
NP_006353                                                              15    9605
NP_001243776                                                           15    9605
NP_001269078                                                           15    9605
NP_001083                                                              15    9605
XP_006725360                                                           15    9605
XP_006725359                                                           15    9605
XP_006725358                                                           15    9605
XP_006725357                                                           15    9605
XP_006725356                                                           15    9605
XP_006725355                                                           15    9605
XP_006721575                                                           15    9605
XP_006721574                                                           15    9605
XP_006721573                                                           15    9605
XP_006721572                                                           15    9605
XP_006721571                                                           15    9605
XP_006721570                                                           15    9605
XP_006721569                                                           15    9605
XP_006718483                                                           15    9605
XP_006718482                                                           15    9605
XP_006718481                                                           15    9605
NP_001010889                                                           15    9605

>NP_001120972
          Length = 1408

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LNIVSFLF 9
           LNIVSFLF
Sbjct: 762 LNIVSFLF 769



>XP_006716051
          Length = 1427

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LNIVSFLF 9
           LNIVSFLF
Sbjct: 781 LNIVSFLF 788



>NP_077026
          Length = 350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNIVSFLF 9
           S+NI+ F+F
Sbjct: 147 SVNILQFIF 155



>NP_115897
          Length = 350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNIVSFLF 9
           S+NI+ F+F
Sbjct: 147 SVNILQFIF 155



>NP_001269231
          Length = 173

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNIVSFLF 9
           S+NI+ F+F
Sbjct: 147 SVNILQFIF 155



>NP_001167563
          Length = 291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SLNIVSFLF 9
          S+NI+ F+F
Sbjct: 88 SVNILQFIF 96



>XP_006724915
          Length = 234

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SLNIVSFLF 9
          S+NI+ F+F
Sbjct: 31 SVNILQFIF 39



>XP_006724914
          Length = 267

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SLNIVSFLF 9
          S+NI+ F+F
Sbjct: 64 SVNILQFIF 72



>XP_006724913
          Length = 267

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SLNIVSFLF 9
          S+NI+ F+F
Sbjct: 64 SVNILQFIF 72



>NP_055137
          Length = 402

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLNIVSFLF 9
           +++IVS+LF
Sbjct: 289 TISIVSYLF 297



>NP_060141
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LNIVSFL 8
           LNI+SFL
Sbjct: 487 LNILSFL 493



>NP_008849
          Length = 299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LNIVSFLF 9
           ++I+SFLF
Sbjct: 121 VSIISFLF 128



>NP_001020127
          Length = 299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LNIVSFLF 9
           ++I+SFLF
Sbjct: 121 VSIISFLF 128



>NP_001013425
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLNIVSFL 8
           S+N VSFL
Sbjct: 274 SMNSVSFL 281



>NP_068781
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 768 NLITFLF 774



>NP_001153218
          Length = 813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 722 NLITFLF 728



>NP_006353
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LNIVSFL 8
           LN+V+FL
Sbjct: 460 LNVVAFL 466



>NP_001243776
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 219 NLITFLF 225



>NP_001269078
          Length = 641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 550 NLITFLF 556



>NP_001083
          Length = 822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 731 NLITFLF 737



>XP_006725360
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 678 NLITFLF 684



>XP_006725359
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 722 NLITFLF 728



>XP_006725358
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 722 NLITFLF 728



>XP_006725357
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 731 NLITFLF 737



>XP_006725356
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 768 NLITFLF 774



>XP_006725355
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 780 NLITFLF 786



>XP_006721575
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 678 NLITFLF 684



>XP_006721574
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 722 NLITFLF 728



>XP_006721573
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 722 NLITFLF 728



>XP_006721572
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 731 NLITFLF 737



>XP_006721571
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NIVSFLF 9
           N+++FLF
Sbjct: 768 NLITFLF 774



>XP_006721570
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    NIVSFLF 9
            N+++FLF
Sbjct: 1027 NLITFLF 1033



>XP_006721569
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    NIVSFLF 9
            N+++FLF
Sbjct: 1027 NLITFLF 1033



>XP_006718483
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LNIVSFL 8
           LN+V+FL
Sbjct: 460 LNVVAFL 466



>XP_006718482
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LNIVSFL 8
           LN+V+FL
Sbjct: 460 LNVVAFL 466



>XP_006718481
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LNIVSFL 8
           LN+V+FL
Sbjct: 460 LNVVAFL 466



>NP_001010889
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLNIVSFL 8
           S+N VSFL
Sbjct: 274 SMNSVSFL 281



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.153    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 365,258
Number of extensions: 458
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)