Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              17    4312
NP_005913                                                              17    4312
XP_005267046                                                           17    4312
XP_005267045                                                           17    4312
NP_001229295                                                           15    9605
NP_542400                                                              15    9605
XP_005277843                                                           15    9605
XP_005252857                                                           15    9605
XP_006718211                                                           15    9605
>NP_006715
          Length = 1558

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLLSIKLLV 9
           SLLSIK LV
Sbjct: 644 SLLSIKQLV 652
>NP_005913
          Length = 1608

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLLSIKLLV 9
           SLLSIK LV
Sbjct: 644 SLLSIKQLV 652
>XP_005267046
          Length = 1554

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLLSIKLLV 9
           SLLSIK LV
Sbjct: 644 SLLSIKQLV 652
>XP_005267045
          Length = 1604

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLLSIKLLV 9
           SLLSIK LV
Sbjct: 644 SLLSIKQLV 652
>NP_001229295
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLLSIKLL 8
           SLL++KLL
Sbjct: 318 SLLALKLL 325
>NP_542400
          Length = 459

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLLSIKLL 8
           SLL++KLL
Sbjct: 318 SLLALKLL 325
>XP_005277843
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SLLSIKLL 8
           SLL++KLL
Sbjct: 318 SLLALKLL 325
>XP_005252857
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LLSIKLLV 9
          LLS+KLL+
Sbjct: 70 LLSLKLLL 77
>XP_006718211
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LLSIKLLV 9
          LLS+KLL+
Sbjct: 70 LLSLKLLL 77
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.147    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 296,209
Number of extensions: 291
Number of successful extensions: 9
Number of sequences better than 10000.0: 9
Number of HSP's gapped: 9
Number of HSP's successfully gapped: 9
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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