Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_085144                                                              17    4312
NP_006682                                                              16    5631
NP_001161444                                                           16    5631
NP_079193                                                              16    5631
NP_001161443                                                           16    5631
NP_001161442                                                           16    5631
NP_061756                                                              16    5631
XP_005262258                                                           16    5631
XP_005262257                                                           16    5631
XP_005262256                                                           16    5631
XP_006724770                                                           16    5631
XP_005262254                                                           16    5631
XP_006724769                                                           16    5631
XP_005262253                                                           16    5631
XP_006724768                                                           16    5631
XP_005262252                                                           16    5631
NP_061993                                                              16    5631
NP_597996                                                              16    5631
NP_065996                                                              16    7355
XP_005270063                                                           16    7355
XP_005270062                                                           16    7355
XP_005270061                                                           16    7355
NP_001073991                                                           15    9605
NP_001127696                                                           15    9605
NP_004810                                                              15    9605
NP_066568                                                              15    9605
NP_001139470                                                           15    9605
NP_803430                                                              15    9605
NP_803429                                                              15    9605
NP_803252                                                              15    9605
NP_001127697                                                           15    9605
NP_004018                                                              15    9605
NP_076435                                                              15    9605
NP_001557                                                              15    9605
XP_005259343                                                           15    9605
XP_005248236                                                           15    9605
XP_005248234                                                           15    9605
XP_006713799                                                           15    9605
XP_005247779                                                           15    9605
XP_006712572                                                           15    9605
XP_006712571                                                           15    9605
XP_006712570                                                           15    9605
XP_006712569                                                           15    9605
XP_006712568                                                           15    9605
XP_006712567                                                           15    9605
XP_006712566                                                           15    9605
XP_006712565                                                           15    9605
XP_006712564                                                           15    9605
XP_006712563                                                           15    9605
XP_006712562                                                           15    9605
>NP_085144
          Length = 343

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SLLGLSLA 8
          SLLGL+LA
Sbjct: 92 SLLGLALA 99
>NP_006682
          Length = 322

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          LLGLSLA
Sbjct: 63 LLGLSLA 69
>NP_001161444
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 357 VIGLSLAQ 364
>NP_079193
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 357 VIGLSLAQ 364
>NP_001161443
          Length = 459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 312 VIGLSLAQ 319
>NP_001161442
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 357 VIGLSLAQ 364
>NP_061756
          Length = 798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          LLGLSLA
Sbjct: 20 LLGLSLA 26
>XP_005262258
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 118 VIGLSLAQ 125
>XP_005262257
          Length = 385

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 238 VIGLSLAQ 245
>XP_005262256
          Length = 447

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 300 VIGLSLAQ 307
>XP_006724770
          Length = 459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 312 VIGLSLAQ 319
>XP_005262254
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 357 VIGLSLAQ 364
>XP_006724769
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 357 VIGLSLAQ 364
>XP_005262253
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 357 VIGLSLAQ 364
>XP_006724768
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 357 VIGLSLAQ 364
>XP_005262252
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLGLSLAQ 9
           ++GLSLAQ
Sbjct: 357 VIGLSLAQ 364
>NP_061993
          Length = 801

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          LLGLSLA
Sbjct: 20 LLGLSLA 26
>NP_597996
          Length = 563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SLLGLSL 7
           SLLGLSL
Sbjct: 168 SLLGLSL 174
>NP_065996
          Length = 3184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLGLSLAQ 9
           LLGL LAQ
Sbjct: 509 LLGLLLAQ 516
>XP_005270063
          Length = 2005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLGLSLAQ 9
           LLGL LAQ
Sbjct: 509 LLGLLLAQ 516
>XP_005270062
          Length = 3184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLGLSLAQ 9
           LLGL LAQ
Sbjct: 509 LLGLLLAQ 516
>XP_005270061
          Length = 3184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLGLSLAQ 9
           LLGL LAQ
Sbjct: 509 LLGLLLAQ 516
>NP_001073991
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SLLGLSL 7
            S+LGLSL
Sbjct: 1005 SILGLSL 1011
>NP_001127696
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>NP_004810
          Length = 1274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LLGLSLAQ 9
            L+GL LAQ
Sbjct: 1138 LIGLRLAQ 1145
>NP_066568
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SLLGLSL 7
           SL+GLSL
Sbjct: 146 SLIGLSL 152
>NP_001139470
          Length = 698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SLLGLSL 7
           SL+GLSL
Sbjct: 115 SLIGLSL 121
>NP_803430
          Length = 116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LLGLSLAQ 9
          L+GL LAQ
Sbjct: 12 LMGLPLAQ 19
>NP_803429
          Length = 116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LLGLSLAQ 9
          L+GL LAQ
Sbjct: 12 LMGLPLAQ 19
>NP_803252
          Length = 116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LLGLSLAQ 9
          L+GL LAQ
Sbjct: 12 LMGLPLAQ 19
>NP_001127697
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>NP_004018
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>NP_076435
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LLGLSLAQ 9
          L+GL LAQ
Sbjct: 12 LMGLPLAQ 19
>NP_001557
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_005259343
          Length = 1274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LLGLSLAQ 9
            L+GL LAQ
Sbjct: 1138 LIGLRLAQ 1145
>XP_005248236
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SLLGLSL 7
            S+LGLSL
Sbjct: 1005 SILGLSL 1011
>XP_005248234
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SLLGLSL 7
            S+LGLSL
Sbjct: 1005 SILGLSL 1011
>XP_006713799
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SLLGLSL 7
           SL+GLSL
Sbjct: 146 SLIGLSL 152
>XP_005247779
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SLLGLSL 7
           SL+GLSL
Sbjct: 146 SLIGLSL 152
>XP_006712572
          Length = 933

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_006712571
          Length = 935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_006712570
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_006712569
          Length = 944

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_006712568
          Length = 946

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_006712567
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_006712566
          Length = 978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_006712565
          Length = 983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_006712564
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_006712563
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
>XP_006712562
          Length = 994

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLGLSLA 8
          +LGLSLA
Sbjct: 29 MLGLSLA 35
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.133    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 397,369
Number of extensions: 549
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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