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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001034976                                                           17    4312
NP_061971                                                              16    5631
NP_938023                                                              16    5631
NP_073624                                                              16    7355
NP_000495                                                              16    7355
NP_001273538                                                           16    7355
NP_115507                                                              16    7355
NP_001137391                                                           16    7355
NP_858043                                                              16    7355
XP_006720027                                                           16    7355
XP_006715637                                                           16    7355
XP_005267214                                                           16    7355
XP_005267213                                                           16    7355
XP_006715636                                                           16    7355
XP_005267212                                                           16    7355
XP_005267211                                                           16    7355
XP_006710887                                                           16    7355
NP_005420                                                              15    9605
NP_078964                                                              15    9605
NP_001177755                                                           15    9605
NP_001177756                                                           15    9605
XP_005260566                                                           15    9605
XP_005252650                                                           15    9605
XP_006717569                                                           15    9605
XP_006717568                                                           15    9605
XP_006717567                                                           15    9605
NP_071389                                                              15    9605
NP_077289                                                              15    9605

>NP_001034976
          Length = 480

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLKTKAMP 8
           SLK KA+P
Sbjct: 322 SLKAKALP 329



>NP_061971
          Length = 809

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SLKTKAMP 8
          SLKTK+ P
Sbjct: 52 SLKTKSTP 59



>NP_938023
          Length = 379

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLKTKAMP 8
           SLKT A+P
Sbjct: 345 SLKTSAVP 352



>NP_073624
          Length = 279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KTKAMPR 9
           KTKA+P+
Sbjct: 144 KTKAVPK 150



>NP_000495
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SLKTKAMPR 9
           S+KT+ +P+
Sbjct: 465 SMKTRGLPK 473



>NP_001273538
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LKTKAMPR 9
          L+TKA+P+
Sbjct: 80 LQTKAVPK 87



>NP_115507
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKTKAMPR 9
           L+TKA+P+
Sbjct: 245 LQTKAVPK 252



>NP_001137391
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKTKAMPR 9
           L+TKAM R
Sbjct: 128 LRTKAMAR 135



>NP_858043
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKTKAMPR 9
           L+TKAM R
Sbjct: 128 LRTKAMAR 135



>XP_006720027
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SLKTKAMPR 9
           S+KT+ +P+
Sbjct: 421 SMKTRGLPK 429



>XP_006715637
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LKTKAMPR 9
          L+TKA+P+
Sbjct: 80 LQTKAVPK 87



>XP_005267214
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LKTKAMPR 9
          L+TKA+P+
Sbjct: 80 LQTKAVPK 87



>XP_005267213
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKTKAMPR 9
           L+TKA+P+
Sbjct: 245 LQTKAVPK 252



>XP_006715636
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKTKAMPR 9
           L+TKA+P+
Sbjct: 245 LQTKAVPK 252



>XP_005267212
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKTKAMPR 9
           L+TKA+P+
Sbjct: 245 LQTKAVPK 252



>XP_005267211
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKTKAMPR 9
           L+TKA+P+
Sbjct: 245 LQTKAVPK 252



>XP_006710887
          Length = 279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KTKAMPR 9
           KTKA+P+
Sbjct: 144 KTKAVPK 150



>NP_005420
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KTKAMPR 9
           KT+ MPR
Sbjct: 128 KTQCMPR 134



>NP_078964
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KTKAMPR 9
           KTK +PR
Sbjct: 115 KTKKLPR 121



>NP_001177755
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KTKAMPR 9
           KT+A+PR
Sbjct: 167 KTEAVPR 173



>NP_001177756
          Length = 226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KTKAMPR 9
          KT+A+PR
Sbjct: 10 KTEAVPR 16



>XP_005260566
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KTKAMPR 9
           KT+A+PR
Sbjct: 167 KTEAVPR 173



>XP_005252650
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KTKAMPR 9
           KTK +PR
Sbjct: 115 KTKKLPR 121



>XP_006717569
          Length = 1278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KTKAMPR 9
           KTK +PR
Sbjct: 701 KTKKLPR 707



>XP_006717568
          Length = 1314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KTKAMPR 9
           KTK +PR
Sbjct: 737 KTKKLPR 743



>XP_006717567
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KTKAMPR 9
           KTK +PR
Sbjct: 808 KTKKLPR 814



>NP_071389
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KTKAMPR 9
           KT+A+PR
Sbjct: 167 KTEAVPR 173



>NP_077289
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TKAMPR 9
           TKA+PR
Sbjct: 145 TKALPR 150



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.118    0.310 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 442,027
Number of extensions: 826
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)