Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_038476                                                              17    2528
NP_872589                                                              17    2528
NP_776159                                                              17    4312
NP_005575                                                              16    5631
NP_079089                                                              16    5631
XP_005271280                                                           16    5631
XP_006710968                                                           16    5631
NP_001229342                                                           16    7355
NP_006248                                                              16    7355
NP_001269574                                                           16    7355
NP_001269573                                                           16    7355
NP_997719                                                              16    7355
XP_005252554                                                           16    7355
XP_006717528                                                           16    7355
XP_005252553                                                           16    7355
NP_775831                                                              15    9605
NP_892006                                                              15    9605
NP_149062                                                              15    9605
NP_001273387                                                           15    9605
NP_853559                                                              15    9605
NP_071375                                                              15    9605
NP_001257348                                                           15    9605
NP_065385                                                              15    9605
NP_003461                                                              15    9605
NP_001273386                                                           15    9605
XP_005255529                                                           15    9605
XP_005255527                                                           15    9605
XP_005255528                                                           15    9605
XP_005255185                                                           15    9605
XP_006715908                                                           15    9605
XP_006715907                                                           15    9605
XP_005250182                                                           15    9605
XP_006715488                                                           15    9605
XP_006715487                                                           15    9605
XP_006715486                                                           15    9605
XP_006715485                                                           15    9605
XP_006715484                                                           15    9605
XP_006715483                                                           15    9605
XP_006715482                                                           15    9605
XP_006715481                                                           15    9605
XP_006715480                                                           15    9605
XP_006715479                                                           15    9605
XP_006715478                                                           15    9605
XP_006715477                                                           15    9605
XP_006715476                                                           15    9605
XP_006715475                                                           15    9605
XP_006715474                                                           15    9605
XP_006715473                                                           15    9605
XP_006715472                                                           15    9605
XP_006715471                                                           15    9605
XP_006715470                                                           15    9605
NP_653275                                                              15    9605
>NP_038476
          Length = 1556

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LKLRIRDF 9
           L+LR+RDF
Sbjct: 975 LELRLRDF 982
>NP_872589
          Length = 1524

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LKLRIRDF 9
           L+LR+RDF
Sbjct: 943 LELRLRDF 950
>NP_776159
          Length = 402

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKLRIRDF 9
           L+LR++DF
Sbjct: 188 LRLRLKDF 195
>NP_005575
          Length = 359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LKLRIRD 8
           +KLRIRD
Sbjct: 158 VKLRIRD 164
>NP_079089
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           L LRIR+F
Sbjct: 459 LNLRIREF 466
>XP_005271280
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           L LRIR+F
Sbjct: 459 LNLRIREF 466
>XP_006710968
          Length = 579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           L LRIR+F
Sbjct: 459 LNLRIREF 466
>NP_001229342
          Length = 643

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           +KL+I DF
Sbjct: 373 IKLKIEDF 380
>NP_006248
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           +KL+I DF
Sbjct: 373 IKLKIEDF 380
>NP_001269574
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           +KL+I DF
Sbjct: 248 IKLKIEDF 255
>NP_001269573
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           +KL+I DF
Sbjct: 337 IKLKIEDF 344
>NP_997719
          Length = 291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SLKLRIRDF 9
           ++KL++ DF
Sbjct: 129 NIKLKVEDF 137
>XP_005252554
          Length = 697

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           +KL+I DF
Sbjct: 407 IKLKIEDF 414
>XP_006717528
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           +KL+I DF
Sbjct: 373 IKLKIEDF 380
>XP_005252553
          Length = 740

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           +KL+I DF
Sbjct: 407 IKLKIEDF 414
>NP_775831
          Length = 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLKLRIRDF 9
           SLK R +DF
Sbjct: 487 SLKKRAQDF 495
>NP_892006
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3170 NLKIQMKDF 3178
>NP_149062
          Length = 8749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>NP_001273387
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           LK++I DF
Sbjct: 782 LKMKITDF 789
>NP_853559
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SLKLRIRD 8
           S+K+RI D
Sbjct: 156 SIKIRIHD 163
>NP_071375
          Length = 975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LKLRIRD 8
           L+LR+RD
Sbjct: 657 LRLRLRD 663
>NP_001257348
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SLKLRIRD 8
           S+K+RI D
Sbjct: 156 SIKIRIHD 163
>NP_065385
          Length = 731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KLRIRDF 9
           +LR RDF
Sbjct: 653 RLRFRDF 659
>NP_003461
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           LK++I DF
Sbjct: 881 LKMKITDF 888
>NP_001273386
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKLRIRDF 9
           LK++I DF
Sbjct: 865 LKMKITDF 872
>XP_005255529
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LKLRIRD 8
           L+LR+RD
Sbjct: 239 LRLRLRD 245
>XP_005255527
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LKLRIRD 8
           L+LR+RD
Sbjct: 541 LRLRLRD 547
>XP_005255528
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LKLRIRD 8
           L+LR+RD
Sbjct: 685 LRLRLRD 691
>XP_005255185
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLKLRIRD 8
           +LKLR+R+
Sbjct: 201 TLKLRLRE 208
>XP_006715908
          Length = 237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SLKLRIRD 8
          S+K+RI D
Sbjct: 76 SIKIRIHD 83
>XP_006715907
          Length = 237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SLKLRIRD 8
          S+K+RI D
Sbjct: 76 SIKIRIHD 83
>XP_005250182
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SLKLRIRD 8
           S+K+RI D
Sbjct: 156 SIKIRIHD 163
>XP_006715488
          Length = 8721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715487
          Length = 8744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715486
          Length = 8758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715485
          Length = 8793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3124 NLKIQMKDF 3132
>XP_006715484
          Length = 8794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715483
          Length = 8795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715482
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3170 NLKIQMKDF 3178
>XP_006715481
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3130 NLKIQMKDF 3138
>XP_006715480
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715479
          Length = 8804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715478
          Length = 8809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715477
          Length = 8822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3153 NLKIQMKDF 3161
>XP_006715476
          Length = 8823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715475
          Length = 8827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715474
          Length = 8829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3160 NLKIQMKDF 3168
>XP_006715473
          Length = 8832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715472
          Length = 8839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3170 NLKIQMKDF 3178
>XP_006715471
          Length = 8842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>XP_006715470
          Length = 8846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    SLKLRIRDF 9
            +LK++++DF
Sbjct: 3177 NLKIQMKDF 3185
>NP_653275
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLKLRIRD 8
           +LKLR+R+
Sbjct: 428 TLKLRLRE 435
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.157    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 429,840
Number of extensions: 784
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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