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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004904                                                              17    2528
XP_005256388                                                           17    2528
XP_005256387                                                           17    2528
XP_006721413                                                           17    2528
XP_005256386                                                           17    2528
NP_001137499                                                           17    4312
NP_055249                                                              17    4312
NP_001137498                                                           17    4312
XP_006717120                                                           17    4312
XP_006717119                                                           17    4312
XP_005266123                                                           17    4312
NP_001166146                                                           16    5631
NP_001166145                                                           16    5631
NP_115973                                                              16    5631
XP_005259393                                                           16    5631
XP_005259392                                                           16    5631
XP_006723494                                                           16    5631
XP_006723493                                                           16    5631
XP_006723482                                                           16    5631
XP_005259380                                                           16    5631
XP_005259381                                                           16    5631
XP_005259373                                                           16    5631
XP_006723481                                                           16    5631
XP_006723480                                                           16    5631
NP_115799                                                              16    5631
NP_001096121                                                           16    7355
XP_006722698                                                           16    7355
XP_006722697                                                           16    7355
NP_001172048                                                           15    9605
NP_001172047                                                           15    9605
NP_061127                                                              15    9605
NP_079316                                                              15    9605
XP_005258464                                                           15    9605
XP_005255923                                                           15    9605
XP_005247681                                                           15    9605
XP_005247679                                                           15    9605
XP_005247678                                                           15    9605
NP_005764                                                              15    9605
NP_056066                                                              15    9605

>NP_004904
          Length = 631

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SLISSLVTH 9
           SL++SLV+H
Sbjct: 267 SLVTSLVSH 275



>XP_005256388
          Length = 466

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SLISSLVTH 9
           SL++SLV+H
Sbjct: 101 SLVTSLVSH 109



>XP_005256387
          Length = 562

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SLISSLVTH 9
           SL++SLV+H
Sbjct: 197 SLVTSLVSH 205



>XP_006721413
          Length = 597

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SLISSLVTH 9
           SL++SLV+H
Sbjct: 267 SLVTSLVSH 275



>XP_005256386
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SLISSLVTH 9
           SL++SLV+H
Sbjct: 267 SLVTSLVSH 275



>NP_001137499
          Length = 521

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 351 SIASSLLTH 359



>NP_055249
          Length = 597

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 385 SIASSLLTH 393



>NP_001137498
          Length = 606

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 385 SIASSLLTH 393



>XP_006717120
          Length = 555

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 334 SIASSLLTH 342



>XP_006717119
          Length = 615

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 403 SIASSLLTH 411



>XP_005266123
          Length = 624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 403 SIASSLLTH 411



>NP_001166146
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 801 SICSSLTTH 809




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 552 SVYSSLTTH 560



>NP_001166145
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 801 SICSSLTTH 809




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 552 SVYSSLTTH 560



>NP_115973
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 800 SICSSLTTH 808




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 551 SVYSSLTTH 559



>XP_005259393
          Length = 781

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 742 SICSSLTTH 750




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 493 SVYSSLTTH 501



>XP_005259392
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 800 SICSSLTTH 808




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 551 SVYSSLTTH 559



>XP_006723494
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 801 SICSSLTTH 809




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 552 SVYSSLTTH 560



>XP_006723493
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 801 SICSSLTTH 809




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           S+ SSL TH
Sbjct: 552 SVYSSLTTH 560



>XP_006723482
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 130 SVRSSLITH 138



>XP_005259380
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 301 SVRSSLITH 309



>XP_005259381
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 301 SVRSSLITH 309



>XP_005259373
          Length = 664

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 399 SVRSSLITH 407



>XP_006723481
          Length = 712

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 447 SVRSSLITH 455



>XP_006723480
          Length = 748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 483 SVRSSLITH 491



>NP_115799
          Length = 628

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLISSLVTH 9
           S+ SSL+TH
Sbjct: 363 SVRSSLITH 371



>NP_001096121
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSLVTH
Sbjct: 505 SSLVTH 510



>XP_006722698
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSLVTH
Sbjct: 355 SSLVTH 360



>XP_006722697
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSLVTH
Sbjct: 504 SSLVTH 509



>NP_001172048
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 456 SSLITH 461



>NP_001172047
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 456 SSLITH 461



>NP_061127
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 456 SSLITH 461



>NP_079316
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 272 SSLITH 277



>XP_005258464
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 127 SSLITH 132




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 183 SSLITH 188




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 211 SSLITH 216



>XP_005255923
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           SL++  VTH
Sbjct: 380 SLVAETVTH 388



>XP_005247681
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 342 SSLITH 347



>XP_005247679
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 374 SSLITH 379



>XP_005247678
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 456 SSLITH 461



>NP_005764
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 280 SSLITH 285




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 336 SSLITH 341




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SSLVTH 9
           SSL+TH
Sbjct: 364 SSLITH 369



>NP_056066
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLISSLVTH 9
           SL++  VTH
Sbjct: 536 SLVAETVTH 544



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.122    0.298 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 336,602
Number of extensions: 1074
Number of successful extensions: 50
Number of sequences better than 10000.0: 39
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)